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排序方式: 共有249条查询结果,搜索用时 31 毫秒
41.
M Koohmaraie JA Scanga MJ De La Zerda B Koohmaraie L Tapay V Beskhlebnaya T Mai K Greeson M Samadpour 《Journal of food protection》2012,75(8):1464-1468
The objective of this study was to determine the source(s) of Salmonella contamination in ground beef. One hundred dairy cows were harvested in a U.S. commercial beef processing plant. Samples of hides, carcasses after hide removal and before exposure to antimicrobial intervention, carcasses after all antimicrobial interventions, superficial cervical lymph nodes from the chuck, trim, ground beef, and air were obtained. Ninety-six percent of the hide samples, 47% of the carcasses before intervention, 18% of the lymph nodes, 7.14% of the trim, and 1.67% of the ground beef samples were positive for Salmonella. None of the samples obtained from the carcasses after the full complement of interventions and none of the air samples were positive for Salmonella. All Salmonella-positive samples were subjected to pulsed-field gel electrophoresis, and eight DNA Xba I restriction patterns were identified. The majority of isolates had one of two restriction digest patterns. The strain isolated from ground beef had the same pattern as the strains isolated from hides and from carcasses immediately after hide removal. The Salmonella isolates from trim samples and lymph nodes also had the same restriction digest pattern. These results indicate that hide and lymph nodes are the most likely sources of Salmonella in ground beef. Dressing practices that effectively reduce or eliminate the transfer of bacteria from hide to carcass and elimination of lymph nodes as a component of raw ground beef should be considered as measures to reduce Salmonella contamination of ground beef. Because total elimination of lymph nodes from ground beef is not possible, other approaches should be explored. Easily accessible lymph nodes could be screened for Salmonella very early in the slaughter process. When the results are positive for Salmonella, the corresponding carcasses should be fabricated separately at the end of the production run, and the trim from these carcasses should be subjected to a treatment that destroys Salmonella. 相似文献
42.
Bijan Dargahi 《Water and Environment Journal》2020,34(3):391-399
Floodwater mosquitoes cause serious problems especially the spread of mosquito‐borne diseases. The main challenge is to implement acceptable general mitigation methods. In recent years, encouraging steps have been taken in favour of developing more sustainable measures such as modern biological methods. The novelty of the present study is in suggesting an alternative green method that can eliminate the use of any secondary biological or chemical agents. The method is based on establishing an alternative river regulation scheme that limits flooding of high‐risk lowland areas. A combined hydrodynamic modelling and optimization method gave effective river regulation schemes. The main idea is to maintain the total power production for a modified inflow hydrograph. The approach was applied to a 30‐km reach of the Österdalälven River located in central Sweden. It was found that with the specific constraints of the site a reduction of about 8% of lowland flood areas is possible if the inflow hydrograph is moderately modified by 20%. Higher reductions are possible by further modification of the hydrograph. The proposed method has a general character controlled by the specific site requirements of a critical flow or a water surface elevation. Based on the foregoing information, the method can be applied to similar sites. 相似文献
43.
The primary objective of this study is to evaluate the impacts of the number and arrangement of lanes on freeway exit ramps on the safety performance of freeway diverge areas. The research team collected crash data at 343 freeway segments in the state of Florida. Four different types of exit ramps were considered in this study. They were defined as type 1, type 2, type 3, and type 4 exit ramps respectively. Cross-sectional comparison was conducted for comparing crash frequency, crash rate and crash severity between different types of freeway exit ramps. Crash prediction models were developed to identify the factors that contribute to the crashes reported at selected freeway segments and to provide quantified information regarding the safety impacts of different freeway exit ramps. It was found that the ramp and freeway AADT, posted speed limit on freeway, deceleration lane length, right shoulder width, and the type of exit ramp significantly affected the safety performance of freeway diverge areas. The study demonstrated the safety benefits of using lane-balanced exit ramps. Based on the crash prediction models, replacing a type 1 exit ramp (lane-balanced) with a type 2 exit ramp (not lane-balanced) will increase crash counts at freeway diverge areas by 68.33%. Replacing a type 3 ramp (lane-balanced) with a type 4 ramp (not lane-balanced) will increase crash counts at freeway diverge areas by 32.20%. 相似文献
44.
The comparison of incomplete sensitivities and Genetic algorithms applications in 3D radial turbomachinery blade optimization 总被引:3,自引:0,他引:3
In the present work, a centrifugal pump impeller’s blades shape was redesigned to reach a higher efficiency in turbine mode using two different optimization algorithms: one is a local method as incomplete sensitivities–gradient based optimization algorithm coupled by 3D Navier–Stokes flow solver, and another is a global method as Genetic algorithms and artificial neural network coupled by 3D Navier–Stokes flow solver. New impeller was manufactured and tested in the test rig. Comparison of the local optimization method results with the global optimization method results showed that the gradient based method has detected the global optimum point. Experimental results confirmed the numerical efficiency improvement in all measured points. This study illustrated that the developed gradient based optimization method is efficient for 3D radial turbomachinery blade optimization. 相似文献
45.
Caroline Barau Shirin Leick Claudio Caccia Lolita Portal Valerio Leoni Philippe Le Corvoisier Didier Morin Bijan Ghaleh Sandrine Pons 《International journal of molecular sciences》2022,23(18)
Exercise induces cardioprotection against myocardial infarction, despite obesity, by restoring pro-survival pathways and increasing resistance of mitochondrial permeability transition pore (mPTP) opening at reperfusion. Among the mechanisms involved in the inactivation of these pathways, oxysterols appear interesting. Thus, we investigated the influence of regular exercise on the reperfusion injury salvage kinase (RISK) pathway, oxysterols, and mitochondria, in the absence of ischemia-reperfusion. We also studied 7β-hydroxycholesterol (7βOH) concentration (mass spectrometry) in human lean and obese subjects. Wild-type (WT) and obese (ob/ob) mice were assigned to sedentary conditions or regular treadmill exercise. Exercise significantly increased Akt phosphorylation, whereas 7βOH concentration was reduced. Moreover, exercise induced the translocation of PKCε from the cytosol to mitochondria. However, exercise did not affect the calcium concentration required to open mPTP in the mitochondria, neither in WT nor in ob/ob animals. Finally, human plasma 7βOH concentration was consistent with observations made in mice. In conclusion, regular exercise enhanced the RISK pathway by increasing kinase phosphorylation and PKCε translocation and decreasing 7βOH concentration. This activation needs the combination with stress conditions, i.e., ischemia-reperfusion, in order to inhibit mPTP opening at the onset of reperfusion. The human findings suggest 7βOH as a candidate marker for evaluating cardiovascular risk factors in obesity. 相似文献
46.
Zeshan Alam Chunwei Zhang Bijan Samali 《The Structural Design of Tall and Special Buildings》2020,29(12)
The estimation of critical seismic response of a structure is complicated in nature due to the uncertain distribution of the internal forces under multidirectional seismic excitations. One of the important concerns inherent to this complication is the uncertainty associated with the final design direction as different seismic directions result in different seismic responses. In this regard, this research provides a detailed examination of (1) response‐to‐response and record‐to‐record variability under varying seismic orientations, (2) quantification of seismic response uncertainties and (3) the seismic performance of asymmetric structure in the context of conservative/nonconservative seismic design. With the mentioned research objectives, a realistic case study asymmetric structure under the influence of varying bidirectional seismic excitations was evaluated. It has been argued in this research that the seismic excitations applied at structure's reference axes are very unlikely to demonstrate maximum response for all response quantities simultaneously, even if it results in a peak response for a particular seismic response quantity. This research is particularly helpful for the critical assessment of directionality influence on asymmetric structures prior to making any decision during thestructural design process. Substantial arguments have been presented to emphasize the inclusion of the investigation of seismic response uncertainty in practical design of critical asymmetric structures. 相似文献
47.
Mehri Sohrabi Bijan Eftekhari Yekta Hamidreza Rezaie Mohammad Reza Naimi-Jamal Ajay Kumar Andrea Cochis Marta Miola Lia Rimondini 《Ceramics International》2021,47(9):12526-12536
Injectable bioactive glass-based pastes represent promising biomaterials to fill small bone defects thus improving and speed up the self-healing process. Accordingly, injectable nanocomposite pastes based on bioactive glass-gelatin-3-glycidyloxypropyl trimethoxysilane (GPTMS) were here synthesized via two different glasses 64SiO2. 27CaO. 4MgO. 5P2O5 (mol.%) and 64SiO2.31CaO. 5P2O5 (mol.%). In particular, the effects of MgO on bioactivity, rheology, injectability, disintegration resistance, compressive strength and cellular behaviors were investigated. The results showed that the disintegration resistance and compressive strength of the composite were improved by the replacement of MgO; thus, leading to an increase in the amount of storage modulus (G′) from 26800 to 43400 Pa, equal to an increase in the viscosity of the paste from 136 × 103 to 219 × 103 Pa s. Since the release rate of ions became more controllable, the formation of calcite was decreased after immersion of the Mg bearing samples in the SBF solution. Specimens’ cytocompatibility was firstly verified towards human osteoblasts by metabolic assay as well as visually confirmed by the fluorescent live/dead staining; finally, the ability of human fibroblasts to penetrate within the pores of 3D composites was verified by a migration assay simulating the devices repopulation upon injection in the injured site. 相似文献
48.
Mehri Sohrabi Bijan Eftekhari Yekta Hamid R. Rezaie Mohammad R. Naimi-Jamal 《应用聚合物科学杂志》2020,137(41):49240
Bioactive pastes containing bioactive sol–gel derived glass (BG) and various amounts of chitosan (Cn) and gelatin (Gel) were prepared in this study. To be exact, three pastes were prepared by mixing 25 parts by weight of glass powder with (a) 100 parts by weight of a 3 wt% acetic acid-based chitosan solution, (b) 100 parts by weight of a 3 wt% water-based gelatin solution, and (c) 100 parts by weight of a solution containing equal amounts of the above-mentioned solutions. The bioactivity of the composite samples was evaluated by the immersion of the prepared pastes into the simulated body fluid (SBF) solution. The samples were also analyzed by X-ray diffractometry (XRD), Brunauer–Emmett–Teller (BET), scanning electron microscope (SEM), Fourier transform infrared (FTIR), and atomic absorption spectroscopy (AAS). The results indicated better apatite formation capacity on the glass-/chitosan-/gelatin-injected paste after 14 days. Furthermore, unlike the chitosan containing paste, the gelatin-containing sample was injectable and displayed viscoelastic behavior as determined by conducting the rheology test in oscillation mode. In addition, while chitosan made the paste more viscous, it improved the washout resistance when compared to the gelatin-containing sample. The experimental results also indicate the formation of spherical calcites in the pastes prior to immersion into the SBF solution. 相似文献
49.
In this paper, we present an approximation for the probability of cell loss of heterogeneous bursty traffic in broadband integrated packet networks based on the asynchronous transfer mode. The sources considered here alternate between active and silent periods and are characterized by their peak and average transmission rates. The cell loss probability is obtained by considering only the number of active sources at a given time and computing the amount of traffic that exceeds the link capacity. Since the amount of buffered excess traffic is not considered in this computation, this approximation is actually an upper bound of the cell loss probability. The numerical efficiency of this bound enables it to be used as a measure based on which robust and simple resource allocation strategies can be developed for bursty sources. Comparison of this bound with the simulation results has shown that the bound is close to the actual loss probabilities especially for large burst lengths and high utilizations. 相似文献
50.
Muhammad J. Habib Clement Akogyeram Bijan Ahmadi 《Drug development and industrial pharmacy》1993,19(4):499-505
Indomethacin powders were blended with phospholipids to prepare physical mixtures or made into solid dispersions by the solvent method and their comparative dissolution profiles were studied. Indomethacin exhibited significantly improved dissolution rates in phospholipid coprecipitates compared to either the physical mixtures or the pure indomethacin. The coprecipitates of lecithin-indomethacin 1:16 weight ratio had a 6.5 fold greater initial dissolution rate, and the total amount dissolved after 60 minutes was 140% greater compared to indomethacin alone. Increasing the lecithin content to 1:4 resulted in only a modest additional increase in the initial dissolution rate (40%) and the limiting concentration (14%) 相似文献