The isolation from a unicellular organism, Dictyostelium discoideum, of a highly-related cdc2 gene with characteristics of the PCTAIRE subfamily

Hepatocyte growth factor (HGF) is known to induce the dispersion of epithelial cells, as scatter factor. On the other hand, cadherins play a crucial role in connecting cells together. Two groups of cadherins are involved in epithelial cell adhesion, those locating in adherens junctions (AJ) and in desmosomes. Here, we examined the effect of HGF on the function of these cadherins in keratinocyte cell lines F and 308R, which expressed E- and P-cadherin in AJ (referred to as AJ cadherins) and desmoplakin in desmosomes. In the presence of HGF, these cells spread more extensively than in control cultures and their associations apparently loosened. However, they maintained cell-cell contacts where cadherins and desmoplakin concentrated, although the level of the concentration was reduced by HGF treatment. When antibodies to E- and P-cadherins were added to cultures of these cells without HGF, AJ cadherins were redistributed into non-junctional areas of the cells, but desmoplakin still localized at cell-cell boundaries. When HGF was added together with anti-AJ cadherin antibodies to the cultures, cell-cell contacts were now disrupted. In these cultures, not only AJ cadherins but also desmoplakin were lost at cell-cell contact sites, indicating that HGF can disrupt desmosomal cell-cell adhesion when AJ cadherins are inactive. These results suggest that, although HGF cannot block cadherin-mediated cell-cell adhesion when the entire cadherin system is intact, it might modulate the activities of cadherins, especially, of desmosomal cadherins.     

Introduction.

This article introduces the current issue of Health Psychology. The call for early intervention to prevent adulthood health problems and the need to consider each period of children's lives within its developmental perspective are the main emphases in this special issue of the journal. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Fabrication of Arsenic Sulfide Optical Fiber with Low Hydrogen Impurities

Arsenic sulfide glass optical fibers typically possess extrinsic absorption bands in the infrared wavelength region associated with residual hydrogen and oxygen related impurities, despite using purified precursors. We report a purification process based on the addition of tellurium tetrachloride (TeCl₄) to the glass. During melting, the chlorine from TeCl₄ reacts with the hydrogen impurities to produce volatile products (e.g., HCl) that can be removed by subsequent dynamic distillation. The processing conditions have been modified accordingly to produce optical fibers with significantly reduced loss due to hydrogen sulfide impurity content (1.5 dB/m).     

Modeling transient slag-layer phenomena in the shell/mold gap in continuous casting of steel

Mold-slag friction and fracture may cause heat-transfer variations in continuous casting, which leads to steel shell temperature and stress variations, resulting in surface cracks. Analytical transient models of liquid slag flow and solid slag stress have been coupled with a finite-difference model of heat transfer in the mold, gap, and steel shell to predict transient shear stress, friction, slip, and fracture of the slag layers. The models are validated by comparing with numerical models and plant measurements of mold friction. Using reported slag-fracture strength and time-temperature-transformation (TTT) diagrams, the models are applied to study the effect of casting speed and mold-powder viscosity properties on slag-layer behavior between the oscillating mold wall and the solidifying steel shell. The study finds that liquid-slag lubrication would produce negligible stresses. A lower mold-slag consumption rate leads to high solid friction and results in solid-slag-layer fracture and movement below a critical value. Crystalline slag tends to fracture near the meniscus and glassy slag tends to fracture near the mold exit. A medium casting speed may be the safest to avoid slag fracture, due to its having the lowest critical lubrication consumption rate. The high measured friction force in operating casters could be due to three sources: an intermittent moving solid slag layer, excessive mold taper, or mold misalignment. Other symbols are defined in Table I     

高清晰光盘格式陷入“低水平”竞争

蓝色激光（Blu-ray，简称蓝光，以下同）光盘和HD DVD均开始进入量产，但格式大战的赢家还不明朗。红色激光：简称红光，以下同）格式仍是某些应用的可靠替代方案，但用户版权限制和显示器与视觉的限制使格式的未来令人疑惑。     

Defensiveness, trait anxiety, and Epstein-Barr viral capsid antigen antibody titers in healthy college students.

Investigated the relationship of individual differences in repressive coping styles with differences in antibody titer to Epstein-Barr (EB) viral capsid antigen in a normal, healthy college population made up of people previously exposed to EB. Each of 54 1st-yr undergraduates completed a battery of physical-status questions and items pertaining to potential behavioral immunomodulatory confounds, along with the Taylor Manifest Anxiety Scale and the Marlowe-Crowne Social Desirability Scale. Ss reporting high and middle levels of anxiety had higher antibody titers to EB, suggesting poorer immune control over the latent virus, as compared with the low-anxious group. Similarly, high-defensive Ss had higher antibody titers than their low-defensive counterparts, and neither group differed from the middle group. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Effect of stepper lens operating conditions on proximity effects in DUV optical lithography down to 250nm

Reduction of optical proximity effects (OPE), at deep uv wavelength of 248nm, caused by the variation of stepper lens operating conditions is investigated. It is shown that many of these effects, which increase as the Rayleigh limit is approached, can be minimised, and in many cases eliminated, by suitable choice of lens numerical aperture (NA) and partial coherence (sigma, σ).

Application of these results should enable the user of advanced wafer steppers to carry out high resolution lithography with a minimum of time consuming optical proximity correction (OPC).