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71.
The paper describes and discusses the results of an extensive testing programme on the structural behaviour of timber connections under ISO‐fire. The results of reference tests performed at normal temperature are also presented. From the variety of timber connections multiple shear steel‐to‐timber connections with dowels and slotted‐in steel plates and connections with steel side plates and annular ringed shank nails were experimentally studied. Particular attention was given to the analysis of the efficiency of different strategies in order to increase the fire resistance of the timber connections. The test results showed that unprotected multiple shear steel‐to‐timber connections with dowels designed for normal temperature reached a fire resistance of about 30 min. A reduction of the load level applied during the fire did not lead to a significant increase of the fire resistance. By increasing the side timber members as well as the end distance of the dowels by 40 mm the connections reached a fire resistance of more than 70 min. Connections protected by timber boards or gypsum plasterboards showed a fire resistance of around 60 min. Thus, from a fire design point of view these strategies were favourable in order to increase the fire resistance of the connections significantly. Unprotected connections with steel side plates and annular ringed shank nails failed already after about 12 min due to large deformations of the nails and the steel side plates directly exposed to fire. By protecting the steel side plates using an intumescent paint the fire resistance of the connections was increased to around 30 min. The test results enlarged the experimental background of timber connections in fire significantly. Copyright © 2009 John Wiley & Sons, Ltd. 相似文献
72.
Dr. Sandra Junghänel Sarah Karczewski Sandra Bäcker Prof. Dr. Shirley K. Knauer Prof. Dr. Carsten Schmuck 《Chembiochem : a European journal of chemical biology》2017,18(22):2268-2279
We discovered a new class of artificial peptidic transfection vectors based on an artificial anion-binding motif, the guanidiniocarbonylpyrrole (GCP) cation. This new type of vector is surprisingly smaller than traditional systems, and our previous work suggested that the GCP group was important for promoting critical endosomal escape. We now present here a systematic comparison of similar DNA ligands featuring our GCP oxo-anion-binding motif with DNA ligands only consisting of naturally occurring amino acids. Structure–activity studies showed that the artificial binding motif clearly outperformed natural amino acids such as histidine, lysine, and arginine. It improved the ability to shuttle foreign genetic material into cells, yet successfully mediated endosomal escape. Also, plasmids that were complexed by our artificial ligands were stabilized against cytosolic degradation to some extent. This resulted in the successful expression of plasmid information (comparable to gold standards such as polyethyleneimine). Hence, our study clearly demonstrates the importance of the tailor-made GCP anion-binding site for efficient gene transfection. 相似文献
73.
Design of LTCC with High Thermal Expansion 总被引:1,自引:0,他引:1
Markus Eberstein Carsten Glitzky Marion Gemeinert Torsten Rabe Wolfgang A. Schiller Christina Modes 《International Journal of Applied Ceramic Technology》2009,6(1):1-8
New applications of low-temperature co-fired ceramics (LTCC), such as pressure sensors or integrated functional layers, require materials that possess higher coefficients of thermal expansion (CTE). To fabricate LTCC with elevated CTE, two methods of material design are examined: firstly, glass ceramic composites (GCC), which consist of >50 vol% glass in the starting powder, and, secondly, glass-bonded ceramics (GBC), where glass is added as a sintering aid only. The CTE of GBC is mainly determined by the crystalline component. For GCC, the CTE can be well predicted, if CTE and elastic data of each phase in the microstructure are known. A nonlinear characteristic of the CTE versus phase composition was found with increasing E crystals / E glass ratio and absolute CTE difference between the components. The glass composition and glass amount can be used to compensate the fixed properties of a crystalline material in a desired way. However, because the CTE and permittivity of a glass cannot be chosen independently, an optimum glass composition has to be found. For a given LTCC, it is possible to control the devitrification by shifting the glass composition. In this way, the resulting CTE values can be predicted more exactly and tailoring becomes possible. Different LTCC materials, based on the crystalline compounds Ba(La,Nd)2 Ti4 O12 , ZrO2 (Y-TZP), SiO2 (quartz), and specially developed glasses, possessing an elevated CTE of around 10 × 10−6 K−1 while showing permittivity ɛr between 6 and 63, are introduced. 相似文献
74.
We extend the area of applications of the Abstract Harmonic Analysis to lower bounds on the circuit and decision tree complexity of Boolean functions related to some number theoretic problems. In particular, we prove that deciding if a given integer is square-free and testing co-primality of two integers by unbounded fan-in circuits of bounded depth requires superpolynomial size. 相似文献
75.
Ant Colony Optimization (ACO) is a kind of metaheuristic that has become very popular for solving problems from combinatorial optimization. Solutions for a given problem are constructed by a random walk on a so-called construction graph. This random walk can be influenced by heuristic information about the problem. In contrast to many successful applications, the theoretical foundation of this kind of metaheuristic is rather weak. Theoretical investigations with respect to the runtime behavior of ACO algorithms have been started only recently for the optimization of pseudo-Boolean functions.We present the first comprehensive rigorous analysis of a simple ACO algorithm for a combinatorial optimization problem. In our investigations, we consider the minimum spanning tree (MST) problem and examine the effect of two construction graphs with respect to the runtime behavior. The choice of the construction graph in an ACO algorithm seems to be crucial for the success of such an algorithm. First, we take the input graph itself as the construction graph and analyze the use of a construction procedure that is similar to Broder’s algorithm for choosing a spanning tree uniformly at random. After that, a more incremental construction procedure is analyzed. It turns out that this procedure is superior to the Broder-based algorithm and produces additionally in a constant number of iterations an MST, if the influence of the heuristic information is large enough. 相似文献
76.
Wrosch Carsten; Miller Gregory E.; Lupien Sonia; Pruessner Jens C. 《Canadian Metallurgical Quarterly》2008,27(6):685
Objective: This study examined whether the association between cortisol secretion and changes in physical health symptoms would depend on other factors in a person's life. The authors expected that physical health effects would emerge particularly when cortisol disturbances co-occur in the context of high levels of trait negative affect or poor sleep. Design: Physical symptoms, diurnal cortisol secretion, affective tendencies, and sleep efficiency were assessed in a 2-yr longitudinal study of 184 older adults. Main Outcome Measure: Two-year changes in physical symptoms. Results: High cortisol levels were associated with increases in physical symptoms, but only among participants who experienced high negative affect and poor sleep. Conclusion: Elevated levels of cortisol secretion contribute to older adults' physical symptoms if they co-occur in the context of other emotional and behavioral problems. By contrast, cortisol disturbances may not influence physical symptoms among people who are emotionally well or engage in efficient sleep behaviors. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
77.
Timo Kurz Alex Hakenjos Jrme Krmer Mario Zedda Carsten Agert 《Journal of power sources》2008,180(2):742-747
This work presents a control strategy for PEM fuel cell systems based on simultaneous impedance measurements on single cells. This control strategy distinguishes between flooding and drying of the cells in a stack and helps to run the stack at an optimal operating point. In the presented experiments, it has been found that impedance measurements can detect flooding phenomena in single cells minutes before they can be seen in related polarisation curves. It is shown that impedance measurements at two specific frequencies, one high and one low frequency impedance, are sufficient to predict voltage drops caused by flooding and drying. In flooding mode, the imaginary part of the low frequency impedance changes while the high frequency impedance remains stable and vice versa in drying mode. This technique reduces measuring time compared to the measurement of whole impedance spectra, without losing important information for the control of the system. 相似文献
78.
79.
Carsten Wegener Michael Peter Kennedy Bernd Straube 《Journal of Electronic Testing》2001,17(5):409-416
By their nature, mixed-signal circuits have to be tested for both structural integrity and parametric performance. For the example of data converters we review test pattern selection strategies geared towards structural and performance testing. We introduce a novel test pattern selection strategy that merges both objectives, and by that we achieve a significant reduction in the size of the set of test patterns applied on the production line. 相似文献
80.
Peter Pirsch Carsten Reuter Jens Peter Wittenburg Mark B. Kulaczewski Hans-Joachim Stolberg 《The Journal of VLSI Signal Processing》2001,29(3):157-165
Architectural concepts are presented aimed at future multimedia processing schemes. Starting from an analysis of current and future multimedia applications, specific computational requirements are derived. It will be shown that multimedia applications benefit from an exhaustive and flexible exploitation of parallelism. Three architectural concepts—reconfigurable computing, simultaneous multithreading, and associative controlling—are presented, and their potential to increase further the performance on future multimedia applications is investigated. 相似文献