试谈我国紫菜资源的工业利用

介绍了我国紫菜工业在工艺改进、资源开发、综合利用和深度加工等方面的情况,提出了提高产率、降低物耗、增进效益和增加品种的途径。     

Importance of the Arg-Gly-Asp triplet in human thrombin for maintenance of structure and function

Site-directed mutagenesis was employed to assess the importance of the Arg-Gly-Asp triplet that comprises residues 197 to 199 in the B-chain of thrombin. Properties of the R197E and the D199E variants were compared with those of zeta-thrombin and the inactive S205A variant wherein the active site Ser is replaced by Ala. Relative to zeta-thrombin, the R197E thrombin variant under the assay conditions used exhibits 26% activity toward a small chromogenic substrate, 13% activity in the activation of protein C in the presence of thrombomodulin, < 3% activity in processing fibrinogen, and 1% activity in inducing platelet activation. Thus, the substrate specificity of thrombin was altered by the R197-->E replacement. The D199E variant was essentially inactive. It exhibited only 0.02% of the activity of thrombin toward the chromogenic substrate and its reactivity toward the active site-directed alkylating agent D-Phe-Pro-Arg-CH2Cl was 10,000-fold lower than that of thrombin. Like the inactive S205A thrombin variant, the D199E variant antagonized the interactions of thrombin with hirudin and thrombomodulin, but was a less effective antagonist. The dependence of the antagonism of the thrombin-thrombomodulin interaction on the concentration of D199E thrombin variant provided evidence suggesting the presence of two or more domains in thrombin that independently interact with their counterparts in thrombomodulin. Although the S205A thrombin variant antagonized the action of thrombin on platelets no such activity could be demonstrated for the D199E variant in the concentration range studied (< 800 nm). Comparison of the circular dichroism spectra of zeta-thrombin, the D199E, R197E, and S205A variants indicated that subtle differences in conformation exist between the D199E variant and the other thrombins. These differences in conformation might well account for the altered behavior of the D199E variant with respect to its interactions toward thrombomodulin, hirudin, and platelets.     

在LiBr吸收式制冷机中使用索柯洛夫公式计算传热温差的探讨

目前在LiBr吸收式制冷机设计中，在计算发生器、冷凝器、蒸发器、吸收器、溶液热交换器的传热温差时都无一例外地使用索柯洛夫公式[1]。本文对索柯洛夫公式进行了分析和比较，认为目前该公式使用的意义已不大，直接用对数平均温差计算即可。     

人体步行规律与仿人机器人步态规划

从仿生学角度分析了人体的步行运动规律,提出了一种基于人体运动规律的仿人机器人步态参数设定方法.首先对人体步行运动数据进行捕捉并分析,得出人体各步态参数间的函数关系,以人体步行相似性作为评价指标,提出仿人机器人步态参数的设定方法.其次,通过分析人体在步行过程中的补偿支撑脚偏航力矩的基本原理,提出了基于双臂及腰关节协调运动的仿人机器人偏航力矩补偿算法,以提高仿人机器人行走的稳定性.最后通过仿真及实验验证了所提出的步态规划方法的正确性及有效性.     

物联阿技术在电梯监测报警管理系统中的应用

本文首先对当前城市电梯运营状况作了分析,然后对利用物联网技术监测与管理电梯的必要性进行了探讨。介绍了物联网技术在城市电梯监测报警管理系统中的应用原理,重点描述了无线监测终端的设计和功能。     

FHUQI-Miner: Fast high utility quantitative itemset mining

Applied Intelligence - High utility itemset mining is a popular pattern mining task, which aims at revealing all sets of items that yield a high profit in a transaction database. Although this task...     

Image cipher using image filtering with 3D DNA-based confusion and diffusion strategy

Neural Computing and Applications - In this paper, an image cipher is presented based on DNA sequence operations, image filtering and memrisitve chaotic system. Firstly, plain image is preprocessed...