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81.
RH Rau YL Chan HI Chuang CR Cheng KL Wong KH Wu TT Wei 《Canadian Metallurgical Quarterly》1997,35(2):113-118
While current psychiatric taxonomies recognise a classification of amphetamine dependence, derived from the notion of an alcohol dependence syndrome, little research has validated that such a condition exists for this drug. Current amphetamine users (N = 331), were interviewed using the World Health Organization operationalisation of DSM-III-R substance dependence criteria, and a measure of the psychological components of dependence. Structural analyses indicated that a unidimensional dependence syndrome as assessed by DSM-III-R and DSM-IV criteria exists for amphetamine, and that physiological, psychological and behavioural indicators were all important in accounting for the variance in responses. It was demonstrated that the concept of a dependence syndrome is applicable to amphetamine, and that the inclusion of the amphetamine dependence syndrome in DSM-III-R and DSM-IV is valid. 相似文献
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The Fas receptor is a member of a family of cell death receptors, including tumor necrosis factor receptor I (TNFR I), death receptor 3 and 4 (DR3 and DR4), and cytopathic avian receptor 1 (CAR1). The Fas receptor is composed of several discrete domains, including three cysteine-rich domains (CRDs), a transmembrane domain, and an intracellular domain responsible for transmitting an apoptotic signal. While the mechanism of Fas-mediated cell death has become elucidated, the requirements for Fas ligand binding to the receptor have not been fully defined. Using a series of chimeric Fc-receptor fusion proteins between the human Fas receptor and TNFR I, each cysteine-rich domain of Fas was found to be required for interaction with the Fas ligand. Interestingly, TNFR I CRD1 could partially substitute for the Fas CRD1. The importance of this domain was underscored by the analysis of a Fas extracellular mutation (C66R), which resulted in a complete loss of ligand binding. This mutation was cloned from a human patient suffering from Canale-Smith syndrome, which is characterized by autoimmunity resembling that observed in the lpr and lprcg mice. The localization of essential ligand binding domains in the Fas receptor correlated exactly with the ability of the Fas receptor fusion proteins to prevent cell death mediated by the Fas ligand. 相似文献
84.
Chao C.-J. Wong S.-C. Chen M.-J. Liew B.-K. 《Semiconductor Manufacturing, IEEE Transactions on》1998,11(4):615-623
Interconnect parasitic parameters in integrated circuits have significant impact on circuit speed. An accurate monitoring of these parameters can help to improve interconnect performance during process development, provide information for circuit design, or give useful reference for circuit failure analysis. Existing extraction methods either are destructive (such as SEM measurement) or can determine only partial parasitic parameters (such as large capacitor measurement). In this paper, we present a new method for extracting interconnect parasitic parameters, which can simultaneously determine the interlayer and intralayer capacitances, line resistance, and effective line width. The method is based on two test patterns of the same structure with different dimensions. The structure consumes less wafer area than existing methods. The method shows good agreement with SEM measurement of dielectric thickness in both nonglobal planarized and chemical-mechanical polished processes, and gives accurate prediction of the process spread of a ring oscillator speed over a wafer 相似文献
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目前国内大多数铝加工厂对铝带材冷轧机机前展平辊的作用缺乏足够的认识,甚至弃而不用。本文主要论述展平辊的作用及展平辊重叠量的计算方法。 相似文献
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单嘴精炼装置真空室内卷渣水模型研究 总被引:1,自引:0,他引:1
本文针对长城特殊厂单嘴精炼装置进行了真空室内加渣精炼的卷渣水模型研究。在试验的基础上,首先讨论了真空室内卷渣现象的工艺过程,然后进一步得出了临界吹气量的表达式。研究结果为工业性生产进一步提高钢的质量打下了基础。 相似文献
90.
太钢3#高炉大修改造是集团公司重点外部工程项目之一,工程量大,工期紧,施工场地狭小,而质量要求较高。如何采取科学、经济的设备吊装方案,对整个项目经济指标的实现,意义重大。文章详细介绍了太钢3#高炉重力除尘器大件整体吊装方案。通过实际采用,取得良好的经济效果。 相似文献