Additive noise removal using a novel fuzzy-based filter

The paper proposes a new fuzzy-based two-step filter for restoring images corrupted with additive noise. The goal of the first step is to compute the difference between the central pixel and its neighborhood in a selected window and to compute a fuzzy membership degree for each difference value using a Gaussian membership function. Computed fuzzy membership values are appropriately utilized as weights for each pixel and then computes the weighted average representing the modified value for the current central pixel. The second step is used as an augmented step to the first one and its goal is to improve the result obtained in the first step by reducing the noise in the color component differences without destroying the fine details of the image. The experimental analysis shows that the proposed method gives better results compared to existing advanced filters for additive noise reduction. Both visual, quantitative and qualitative analysis have been done to prove the efficiency and effectiveness of the proposed method.     

Method for prediction of protein-protein interactions in yeast using genomics/proteomics information and feature selection

Protein-protein interaction (PPI) prediction is one of the main goals in the current Proteomics. This work presents a method for prediction of protein-protein interactions through a classification technique known as support vector machines. The dataset considered is a set of positive and negative examples taken from a high reliability source, from which we extracted a set of genomic features, proposing a similarity measure. From this dataset we extracted 26 proteomics/genomics features using well-known databases and datasets. Feature selection was performed to obtain the most relevant variables through a modified method derived from other feature selection methods for classification. Using the selected subset of features, we constructed a support vector classifier that obtains values of specificity and sensitivity higher than 90% in prediction of PPIs, and also providing a confidence score in interaction prediction of each pair of proteins.