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81.
The fragile base-class problem (FBCP) has been described in the literature as a consequence of “misusing” inheritance and composition in object-oriented programming when (re)using frameworks. Many research works have focused on preventing the FBCP by proposing alternative mechanisms for reuse, but, to the best of our knowledge, there is no previous research work studying the prevalence and impact of the FBCP in real-world software systems. The goal of our work is thus twofold: (1) assess, in different systems, the prevalence of micro-architectures, called FBCS, that could lead to two aspects of the FBCP, (2) investigate the relation between the detected occurrences and the quality of the systems in terms of change and fault proneness, and (3) assess whether there exist bugs in these systems that are related to the FBCP. We therefore perform a quantitative and a qualitative study. Quantitatively, we analyse multiple versions of seven different open-source systems that use 58 different frameworks, resulting in 301 configurations. We detect in these systems 112,263 FBCS occurrences and we analyse whether classes playing the role of sub-classes in FBCS occurrences are more change and–or fault prone than other classes. Results show that classes participating in the analysed FBCS are neither more likely to change nor more likely to have faults. Qualitatively, we conduct a survey to confirm/infirm that some bugs are related to the FBCP. The survey involves 41 participants that analyse a total of 104 bugs of three open-source systems. Results indicate that none of the analysed bugs is related to the FBCP. Thus, despite large, rigorous quantitative and qualitative studies, we must conclude that the two aspects of the FBCP that we analyse may not be as problematic in terms of change and fault-proneness as previously thought in the literature. We propose reasons why the FBCP may not be so prevalent in the analysed systems and in other systems in general.  相似文献   
82.
In this paper we present a novel image based algorithm to render visually plausible anti‐aliased soft shadows in a robust and efficient manner. To achieve both high visual quality and high performance, it employs an accurate shadow map filtering method which guarantees smooth penumbrae and high quality anisotropic anti‐aliasing of the sharp transitions. Unlike approaches based on pre‐filtering approximations, our approach does not suffer from light bleeding or losing contact shadows. Discretization artefacts are avoided by creating virtual shadow maps on the fly according to a novel shadow map resolution prediction model. This model takes into account the screen space frequency of the penumbrae via a perceptual metric which has been directly established from an appropriate user study. Consequently, our algorithm always generates shadow maps with minimal resolutions enabling high performance while guarantying high quality. Thanks to this perceptual model, our algorithm can sometimes be faster at rendering soft shadows than hard shadows. It can render game‐like scenes at very high frame rates, and extremely large and complex scenes such as CAD models at interactive rates. In addition, our algorithm is highly scalable, and the quality versus performance trade‐off can be easily tweaked.  相似文献   
83.
In this paper, we present a new irradiance caching scheme using Monte Carlo ray tracing for efficiently rendering participating media. The irradiance cache algorithm is extended to participating media. Our method allows to adjust the density of cached records depending on illumination changes. Direct and indirect contributions can be stored in the records but also multiple scattering. An adaptive shape of the influence zone of records, depending on geometrical features and irradiance variations, is introduced. To avoid a high density of cached records in low interest areas, a new method controls the density of the cache when adding new records. This record density control depends on the interpolation quality and on the photometric characteristics of the medium. Reducing the number of records accelerates both the computation pass and the rendering pass by decreasing the number of queries to the cache data structure (Kd-tree). Finally, instead of using an expensive ray marching to find records that cover the ray, we gather all the contributive records along the ray. With our method, pre-computing and rendering passes are significantly speeded-up.  相似文献   
84.
The Plasmodium falciparum food vacuole (FV) is a lysosome-like organelle where erythrocyte hemoglobin digestion occurs. It is a favorite target in the development of antimalarials. We have used a tandem mass spectrometry approach to investigate the proteome of an FV-enriched fraction and identified 116 proteins. The electron microscopy analysis and the Western blot data showed that the major component of the fraction was the FV and, as expected, the majority of previously known FV markers were recovered. Of particular interest, several proteins involved in vesicle-mediated trafficking were identified, which are likely to play a key role in FV biogenesis and/or FV protein trafficking. Recovery of parasite surface proteins lends support to the cytostomal pathway of hemoglobin ingestion as a FV trafficking route. We have identified 32 proteins described as hypothetical in the databases. This insight into FV protein content provides new clues towards understanding the biological function of this organelle in P. falciparum.  相似文献   
85.
Protein oxidation mechanisms result in a wide array of modifications, from backbone cleavage or protein crosslinking to more subtle modifications such as side chain oxidations. Protein oxidation occurs as part of normal regulatory processes, as a defence mechanism against oxidative stress, or as a deleterious processes when antioxidant defences are overcome. Because blood is continually exposed to reactive oxygen and nitrogen species, blood proteomics should inherently adopt redox proteomic strategies. In this review, we recall the biochemical basis of protein oxidation, review the proteomic methodologies applied to analyse redox modifications, and highlight some physiological and in vitro responses to oxidative stress of various blood components.  相似文献   
86.
87.
Photolithography to produce TiO2 patterns from amorphous films of (5-C5H5)2Ti(N3)2 has been demonstrated. The efficiency of the reaction has been measured yielding a quantum yield of 0.025. The mechanism of the photoreactions of (5-C5H5)2Ti(N3)2 has been studied using Fourier transform-infrared spectroscopy in both a low-temperature 1,2-epoxyethylbenzene glass and as surface films. In each case the primary photochemical process was found to be loss of a single azido group. The result of subsequent photolysis was found to be dependent upon medium and temperature. In the low-temperature glass no further photochemistry was observed. The exhaustive photolysis of films at 20 K, or room temperature, under a vacuum or in air led to loss of all ligands and the formation of TiO2.  相似文献   
88.
This paper presents an assessment method to evaluate the quality of object oriented software systems. The assessment method is based on source code abstraction, object–oriented metrics and graphical representation. The metrics used and the underlying model representing the software are presented. The assessment method experiment is part of an industrial research effort with the Bell Canada Quality Engineering and Research Group. It helps evaluators assess the quality and risks associated with software by identifying code fragments presenting unusual characteristics. The assessment method evaluates object–oriented software systems at three levels of granularity: system level, class level and method level. One large C++ and eight Java software systems, for a total of over one million lines of code, are presented as case studies. A critical analysis of the results is presented comparing the systems and the two languages.  相似文献   
89.
This article presents the result of the current knowledge on the very high frequency electromagnetic radiation of lightning. A phenomenology analysis of the new results obtained from the study of triggered lightning in New Mexico (TRIP 82) and at Saint-Privat-d’ Allier in Haute-Loire, France (1983) is first described. The authors then present the spectral and temporal characteristics of the VHF/UHF radiation which can be applied to the electromagnetic compatibility of systems. From a synthesis of the experimental and theoretical contributions, they propose a reflection on the lightning initiation process and on the mechanisms generating lightning radiation.  相似文献   
90.
The ground-state properties of bulk atomic hydrogen are calculated for the low-density gas, assuming that the atoms interact via the 3 u + pair potential. The Monte Carlo technique is applied to a system consisting of 32 hydrogen atoms in a box, with periodic boundary conditions. These results are compared with those derived from the hard-sphere Bose-Einstein gas model.Work supported by NASA Grant No. NGR 06-002-159.  相似文献   
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