Performance analysis of an improved MMSE multiuser receiver formismatched delay channels

Motivated by the fact that time delays in a practical direct-sequence code-division multiple-access (DS-CDMA) system can never be perfectly estimated, an improved minimum-mean squared-error (MMSE)-based receiver is proposed and analyzed. Via the simple assumption of a probability distribution for the delay estimation errors, the proposed receiver can achieve a performance superior to that of the conventional MMSE (CMMSE) receiver. The performances of this improved receiver and the CMMSE receiver are compared in terms of the mean squared error (MSE), probability of error, and asymptotic multiuser efficiency (AME). As the original definition of AME does not consider mismatched channels, the behavior of three single-user receivers bearing imperfect delay estimation is also investigated. These single-user receivers are employed to define a more appropriate AME. Finally, an efficient update mechanism to accommodate dynamic channel statistics, and thus practical implementation, is proposed     

Pharmacokinetics of hyperimmune anti-human immunodeficiency virus immunoglobulin in persons with AIDS

Hyperimmune anti-human immunodeficiency virus immunoglobulin (HIVIG) is an intravenous immunoglobulin prepared from HIV-infected asymptomatic donors with a CD4 cell count greater than 400 cells/microl and a high titer of antibody to HIV-1 p24 protein. Twelve persons with AIDS received four doses of HMG (two at 50 mg/kg of body weight and then two at 200 mg/kg) every 28 days. Pharmacokinetics were evaluated by measurement of anti-p24 antibody. HIVIG was well tolerated, and all participants completed the study. Three subjects who were not receiving Pneumocystis carinii pneumonia (PCP) prophylaxis developed PCP. The mean value for HIVIG clearance was 3.02 ml/kg/day at 50 mg/kg and 3.65 ml/kg/day at 200 mg/kg (P = 0.027); the mean trough antibody titers (reciprocal units) were 1,442 and 4,428, respectively. This study indicates that high titers of anti-p24 antibody can be maintained with a monthly administration schedule of HIVIG and that short-term safety is acceptable. Comparisons to evaluate the therapeutic potential of HIVIG are justified.     

Analysis of adaptive routing schemes in multirate loss networks

As technology evolves, it is now feasible to implement sophisticated adaptive routing schemes on networks which support different kinds of services with heterogeneous bandwidth characteristics. Adaptive routing can increase the network throughput by routing calls to less congested paths. It can also be used to bypass transmission facility failures. In this paper, we analyze and compare two adaptive routing schemes. The first is called theMaximum mean time to blocking (MTB) routing which is based on themean time to blocking measure of a link. This measure captures the traffic rates, bandwidth characteristic and link capacity information and reflects more accurately the congestion status of different paths. The second is theM ² routing, which is a modification of the least loaded routing (LLR). Aggregation of link status information can significantly reduce signalling traffic. We show in this paper that with properly designed aggregation, the aggregatedM ² and MTB routings can have performance that approach that of the non-aggregated schemes. The use of complete sharing and restricted access policies together with trunk reservation control in multirate loss networks are also studied.     

High speed p-type SiGe modulation-doped field-effect transistors

We report on the fabrication and characterization of high-speed p-type modulation-doped field-effect transistors (MODFETs) with 0.7-μm and 1-μm gate-lengths having unity current-gain cut-off frequencies (f_T) of 9.5 GHz and 5.3 GHz, respectively. The devices were fabricated on a high hole mobility SiGe heterostructure grown by ultra-high-vacuum chemical vapor deposition (UHV-CVD). The dc maximum extrinsic transconductance (g_m) is 105 mS/mm (205 mS/mm) at room temperature (77 K) for the 0.7-μm gate length devices. The fabricated devices show good pinch-off characteristics and have a very low gate leakage current of a few μA/mm at room temperature and a few nA/mm at 77 K     

Optical gain of interdiffused InGaAs-As and AlGaAs-GaAs quantumwells

We have analyzed theoretically the effects of interdiffusion on the gain, differential gain, linewidth enhancement factor, and the injection current density of In_0.2Ga_0.8As-GaAs and Al_0.3Ga_0.7As-GaAs quantum-well (QW) lasers. We have calculated the electron and hole subband structures including the effects of valence band mixing and strains. The optical gain is then calculated using the density matrix approach. Our results show that the gain spectrum can be blue-shifted without an enormous increase in the injected current density. Imposing an upper limit (416 A·cm^-2) on the injection current density for a typical laser structure, we find that the InGaAs-GaAs and AlGaAs-GaAs QW lasers can be blue-shifted by 24 and 54 mn, respectively. Our theoretical results compare well with the tuning ranges of 53 and 66 meV found for AlGaAs-GaAs QWs in some experiments. This indicates that the interdiffusion technique is useful for the tuning of laser operation wavelength for multiwavelength applications     

An improved method for magnetic identification and localization of cracks in conductors

A SQUID magnetometer can be used to measure the magnetic field produced by flaws in a two-dimensional, conducting plate carrying a current. Identification of the flaw-induced magnetic field is difficult because of the large magnetic field associated with the edges of the plate and the current in the leads that connect the plate to the power supply. We have developed a technique by which the wire and edge fields can be cancelled prior to mapping the magnetic field. In this technique, a similar unflawed conducting sheet is placed adjacent to the flawed plate, with a connection between the sheet and the plate at one edge, and with the opposite edges of the sheet and of the plate connected to the two conductors of a coaxial cable. Thus, an applied current will flow along one conductor of the cable, across the cancelling sheet, cross into the flawed plate, return along the plate, and then return to the power supply along the other conductor of the coaxial cable. As a result of this geometry, there is no magnetic field from the lead-in wires because they are coaxial, and the magnetic field due to the edges of the plate is cancelled by the opposing magnetic field of the edges in the adjacent sheet. The extent of cancellation is determined primarily by the separation between the plate and the cancelling sheet, by the thickness of the plate, and by macroscopic inhomogeneities in their electrical conductivities.     

Triangular ray-tube analysis of dielectric lens antennas

A new method of analysis for the radiation characteristics of dielectric lens antennas with arbitrary inner and outer surfaces is presented. The analysis is based on representing the feed illumination by a contiguous set of ray tubes and including the effects of surface reflections and ray divergence. Radiation patterns and the antenna gain are then computed by evaluating the closed-form expressions developed for the Kirchhoff's integral of the aperture fields. The validity of the analysis method has been demonstrated by comparing the computations with measured results of two different spherical lenses and a shaped lens configurations. The analysis method presented takes into account some of the practical aspects associated with lens design such as surface zoning to reduce the mass and surface matching to minimize the reflection loss     

Laparoscopic surgery of adrenal glands: indications and limits

Over the last four years it has been demonstrated that laparoscopy can be used successfully for adrenalectomy, providing certain advantages over conventional open surgery. The aim of this study was to determine the indications for laparoscopic approach in adrenal surgery. From June 1994 to June 1996 laparoscopic transabdominal flank approaches were proposed in patients with a unilateral 8 cm or less, non-malignant tumors of the adrenal gland. For tumors under 4 cm in diameter only secreting tumors were removed. Among 77 patients requiring ablation of the adrenal gland, 50 (65%) underwent a laparoscopic procedure: 29 Conn adenomas, 10 Cushing adenomas, 6 Pheochromocytomas, 4 incidentalomas. One patient had Cushing's disease and underwent bilateral resection. Mean tumor size was 26 mm (7-75 mm). Malignancy was demonstrated in 2 tumors: one cortisone secreting tumor and one leiomyosarcoma. Conversion was required in 4 cases (8%). Mean operative time for unilateral adrenalectomies was 147 minutes (50-300'). There were no deaths. Morbidity included: one hemorrhage via the trocar orifice requiring reoperation, one infarction of the spleen which regressed spontaneously, one parietal hematoma, and one case of phebitis of the lower limb. The endocrinopathy was successfully cured in all patients with secreting tumors. The 27 other patients underwent open adrenalectomy. Laparoscopic approach was not proposed due to suspected malignancy in 13 cases, previous surgery in 8 cases and multiple, bilateral and/or extra adrenal tumors in 6 cases. Laparoscopic approach to the adrenal gland is the procedure of choice in patients with Conn adenomas, Cushing adenomas and in most cases of pheochromocytomas. It is not indicated for malignant and large tumor (> 8 cm). Currently two-thirds of our patients requiring and adrenalectomy are operated laparoscopically.