Self‐healing properties of layer‐by‐layer assembled multilayers

The review is focused on the formation and the self‐healing properties of polymer and hybrid multilayers formed via the layer‐by‐layer approach. In the first part of the review the recent developments in the construction of polymer multilayers are highlighted. In the second part the design and the self‐healing properties of inorganic ? polymer hybrid multilayers are described. It is shown that self‐healing multilayers have a broad spectrum of applications including corrosion protection, as elements of antifouling and antimicrobial coatings and bio‐inspired superhydrophobic interfaces. It is demonstrated that dynamic functional interfaces have a complex hierarchical organization of non‐covalently bonded polymers and colloidal particles. Mechanisms of self‐healing behavior of the multilayers and the role of water and external stimuli (pH, ionic strength and temperature, light) in swelling of multilayers and rearrangement of polymer segments are discussed. Future trends, perspectives and research strategies for the design of ‘smart’ self‐assemblies with self‐healing properties are proposed. © 2015 Society of Chemical Industry     

Design of an integrated quality assurance strategy in production systems

High-quality of products is a critical issue for manufacturers to maintain their competitiveness in global markets. For this reason, more attention has been paid by operations managers and academics to the design of quality assurance strategies, acceptance sampling plans and inspection allocation problems. In the last decades, international research has studied and introduced several models and approaches to investigate these issues. The purpose of this paper is to provide a new methodology for designing and selecting correct integrated quality assurance strategies, defining cost models for acceptance policies and inspection station configurations. Generally, high-quality of items is guaranteed by avoiding defects, mainly caused by non-conforming components, resulting from instantaneous and standard infant mortality. Thus, an optimal acceptance policy is defined in order to reduce the instantaneous infant mortality defects. A closed-form equation has been introduced to determine easily and quickly the optimal percentage of checked items. Furthermore, a more convenient inspection station configuration is determined in order to minimise the expected total cost, composed of testing, inspection and penalty cost elements. The innovative concept of defect rate as an inspection time variable dependent has been introduced. The impact of different economic and survival parameters on designing inspection policies is also investigated. Finally, a real-life case study demonstrates the applicability of this methodology in real production systems and several considerations are reported about the future research, that the authors will carry out.     

Target value design: using collaboration and a lean approach to reduce construction cost

Target costing is an effective management technique that has been used in manufacturing for decades to achieve cost predictability during new product development. Adoption of this technique promises benefits for the construction industry as it struggles to raise the number of successful outcomes and certainty of project delivery in terms of cost, quality and time. Target value design is a management approach that takes the best features of target costing and adapts them to the peculiarities of construction. The concept of target value design is introduced based on the results of action research carried out on 12 construction projects in the USA. It has been shown that systemic application of target value design leads to significant improvement of project performance—the final cost of projects was on average 15% less than market cost. The construction industry already has approaches that have similarities with elements of the target value design process or use the same terminology, e.g. partnering and target cost contracts, cost planning, etc. Following an exploration of the similarities and differences target value design is positioned as a form of target costing for construction that offers a more reliable route to successful project outcomes.     

Effect of dissolved organic carbon on the photoproduction of dissolved gaseous mercury in lakes: potential impacts of forestry

The production of dissolved gaseous mercury (DGM) in freshwater lakes is induced by solar radiation and is also thought to be linked to processes mediated by dissolved organic carbon (DOC). Studies investigating these processes using comparisons between lakes are often confounded by differences in DOC content and structure. In this study, we investigated the link between DOC concentrations and DGM production by using tangential ultrafiltration to manipulate DOC concentrations in water samples taken from a given lake. In this way, a range of samples with different DOC concentrations was produced without substantial changes to DOC structure or dissolved ions. This was repeated for four lakes in central Quebec: two with highly logged drainage basins and two with minimally logged drainage basins. On two separate days for each lake, water samples (filtered to remove >99% of microorganisms) with varying DOC concentrations were incubated in clear and dark Teflon bottles on the lake surface. DGM concentrations were measured at 3.5-h intervals over the course of 10.5 h. Levels of DGM concentrations increased with increasing cumulative irradiation for all lakes until approximately 4000 kJ m(-2) (400-750 nm, photosynthetically active radiation (PAR)), when DGM concentrations reached a plateau (between 20 and 200 pg L(-1)). When we assumed that DGM production was limited by the amount of photoreducible mercury, reversible first-order reaction kinetics fitted the observed data well (r2 ranging between 0.59 and 0.98, p < 0.05 with the exception of N70 100% DOC, 0% DOC, and K2 0% DOC with p = 0.06, 0.10, and 0.11, respectively). The DGM plateaus were independent of DOC concentrations but differed between lakes. In contrast, photoproduction efficiency (DGMprod) (i.e., the amount of DGM produced per unit radiation (fg L(-1) (kJ/m2)(-1)) below 4000 kJ m(-2) PAR) was linearly proportional to DOC concentration for both logged lakes (r2 = 0.97, p < 0.01) and nonlogged lakes (r2 = 0.52, p = 0.018) studied. Furthermore, logged lakes had a lower DGMprod per unit DOC (p < 0.01) than the nonlogged lakes. In these four lakes, the rate of DGM production per unit PAR was dependent on the concentration of DOC. The DGM plateau was independent of DOC concentration; however, there was a significant difference in DGM plateaus between lakes presumably due to different DOC structures and dissolved ions. This research demonstrates an important mechanism by which logging may exacerbate mercury levels in biota.     

Biocompatible Smart Microcapsules Based on Chitosan‐Poly(vinyl alcohol) Copolymers for Cultivation of Animal Cells

In this study, two novel chitosan‐graft‐poly(vinyl alcohol) copolymers are synthesized and used as water‐soluble at physiological conditions polycations for preparation of smart microcapsules. The microcapsules provide growth and proliferation of eight mammalian cell lines, including hybridoma and tumor cells, at long‐term cell cultivation in vitro. The microcapsules are stable in cell culture medium but can be dissolved by changing pH value of the medium (up to 8.0–8.2), thus making possible a simple release of the entrapped cells. Monoclonal antibody production by encapsulated hybridoma cells is demonstrated. Cultivation of tumor cells within the microcapsules allows the formation of 3D multicellular spheroids, which can be proposed as an in vitro model for anticancer drug screening.