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91.
Robert Goldston Mohamed Abdou Charles Baker Michael Campbell Vincent Chan Stephen Dean Amanda Hubbard Robert Iotti Thomas Jarboe John Lindl B. Grant Logan Kathryn McCarthy Farrokh Najmabadi Craig Olson Stewart Prager Ned Sauthoff John Sethian John Sheffield Steven Zinkle 《Journal of Fusion Energy》2002,21(2):61-111
This is the final report of a panel set up by the U.S. Department of Energy (DOE) Fusion Energy Sciences Advisory Committee (FESAC) in response to a charge letter dated September 10, 2002 from Dr. Ray Orbach, Director of the DOE's Office of Science. In that letter, Dr. Orbach asked FESAC to develop a plan with the end goal of the start of operation of a demonstration power plant in approximately 35 years. This report, submitted March 5, 2003, presents such a plan, leading to commercial application of fusion energy by mid-century. The plan is derived from the necessary features of a demonstration fusion power plant and from the time scale defined by President Bush. It identifies critical milestones, key decision points, needed major facilities and required budgets. The report also responds to a request from DOE to FESAC to describe what new or upgraded fusion facilities will best serve our purposes over a time frame of the next twenty years. 相似文献
92.
Vernon DD Diller EM Cook LJ Reading JC Suruda AJ Dean JM 《Accident; analysis and prevention》2002,34(2):237-246
BACKGROUND: Medical problems may affect the ability to drive motor vehicles, and programs that control the issuing of driver licenses to individuals with medical conditions exist in most states. The main activity of these programs is the imposition of restrictions upon the driving privileges of individuals with medical conditions that are deemed to pose some risk to public safety. However, little is known about the effectiveness of these licensing programs. OBJECTIVE: The objective of this study was to compare the rates of adverse driving events (crash, at-fault crash and citations) experienced by drivers licensed with medical conditions to those of age-, sex- and location-matched controls. Separate comparisons were made for drivers reporting medical conditions licensed with full driving privileges, and those with restricted driving privileges (e.g. speed, area and time of day). DESIGN: Retrospective case-control. METHODS: The study population was all drivers licensed in the state of Utah who reported a medical condition on their driver license application, over the 5-year period 1992-1996. Drivers enter the program by self-reporting their medical problems. Control drivers were chosen from the entire population of drivers licensed in Utah for the same period. Information on driver license status, participation in the medical conditions program, citations, involvement in crashes, and death certificate data was obtained from the relevant state agencies. Probabilistic linkage methodology was used to link the records in these disparate databases for eventual analysis. Rates of citation, crashes and at-fault crashes, expressed as events per 10000 license days, were calculated separately for program drivers and their corresponding control groups for each medical condition category and restriction status. These data were used to determine an estimate of relative risk (RR) and 95% confidence intervals. Results: As a group, medical conditions drivers had modestly elevated rates of adverse driving events compared with control drivers (RR 1.09-1.74). Rates in the largest medical category, 'cardiovascular conditions', were not higher than controls. Rates were higher than control for some conditions, such as 'alcohol' and 'learning and memory', for some adverse events (RR 2.2 -5.75). Drivers with more than one medical condition appeared comparable to the general group of medical conditions program drivers. CONCLUSIONS: Drivers in Utah medical conditions program had modestly elevated rates of adverse driving events compared to matched controls. Possible underreporting of medical conditions and accurate assessment of exposure rates are potential weaknesses in the program. 相似文献
93.
In capillary electrokinetic chromatography, neutral analytes can be injected by electroosmotic flow directly from a sample matrix into a separation buffer containing an electrokinetic vector with an opposite mobility. Analytes are injected at the velocity of electroosmotic flow but are retained at the interface of the sample matrix co-ion and separation buffer micelle zones as analyte/micelle complexes. A simple electrokinetic chromatography system containing sodium dodecyl sulfate as the micellar agent with borate as the buffering electrolyte included in the separation buffer and in the sample matrix to provide continuous conductivity was investigated. Concentrations of the micelle, methanol, and borate in the separation buffer were explored to increase maximum injection length of neutral analytes. Reducing the analyte velocity in the separation buffer without substantially decreasing the velocity of the analyte during injection from the sample vial allowed greatly extended sample plug injection lengths. It is presently possible to inject sample solvent volumes equivalent to approximately 7 effective capillary lengths (180 cm) with a 50-microm-i.d. capillary (24.5 cm effective capillary length), total volume of sample injection approximately 3.5 microL Equations describing the injection process and maximum injection lengths for this mode of stacking in electrokinetic capillary chromatography are introduced. The result of this work leads to a postulated generalization of electrokinetic stacking injection maximums for electrophoretic processes, and the concept of orthogonal analyte stacking/injection systems is discussed. 相似文献
94.
在实时监控系统中,数据处理是一项基本功能,对于较复杂的数据计算通常不得不在系统设计期间确定计算的方式和输入变量,这样降低了系统的灵活性。本文介绍了一种通过调用Excel组件实现复杂二次计算的方法,利用此法可使在设计期并不确定二次计算的方式,而在运行中通过数据库的设定和Excel工作表的设计实现各种二次计算。 相似文献
95.
An innovative TPO, based upon a complex fluid, is described, which shows an unusual balance of physical properties. The effects of complex fluid composition are addressed in a statistically designed experiment. Physical performance, rheological effects, thermal analysis, and morphological characterization are reported. J. VINYL ADDIT. TECHNOL., 12:183–191, 2006. © 2006 Society of Plastics Engineers 相似文献
96.
By a strategy suggested by E. H. Uhlenhuth et al (1983), Diagnostic and Statistical Manual of Mental Disorders (DSM-III) referenced syndrome classifications were derived on the basis of the Hopkins Symptoms Checklist—42 scores of 1,131 elderly community residents. Overall syndrome prevalence rates were consistent with other epidemiologic data: 3.9% for depression, 1.0% for agoraphobia-panic, 2.6% for other phobia, and 6.9% for anxiety. Prevalence rates reflected expected sex differences and showed an age trend for other phobias. Considerable comorbidity among syndromes was observed. The association of the syndromes with patterns of psychosocial risk factors, prior diagnoses, and medication suggests that some but not all of the identified syndromes reflect clinically relevant classifications. If further developed, syndrome classifications based on self-report scales can provide inexpensive and clinically relevant measures of caseness. Required refinements of this approach are discussed. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
97.
98.
D Farnbach-Pralong R Bradbury D Copolov B Dean 《Canadian Metallurgical Quarterly》1998,349(2-3):R7-R8
The density of GABA(A) receptors in the hippocampus and the temporal cortex from rats treated for 28 days with either haloperidol, chlorpromazine, clozapine or olanzapine was measured. Compared to haloperidol (0.01 and 0.1 mg kg(-1) day(-1)) and chlorpromazine (0.1 and 1 mg kg(-1) day(-1)), clozapine and olanzapine (0.1 and 1 mg kg(-1) day(-1)) markedly decreased the density of GABA(A) receptors in these two brain regions. These data suggest that modulation of GABAergic transmission could be an important action of some antipsychotic drugs. 相似文献
99.
SR Dean RW Meola SM Meola H Sittertz-Bhatkar R Schenker 《Canadian Metallurgical Quarterly》1998,35(5):720-724
Adult cat fleas, Ctenocephalides felis (Bouché), were fed suboptimal in vitro concentrations of lufenuron in blood to allow hatching of flea larvae for cytological study. At concentrations of 0.125, 0.25, and 0.5 ppm, larval hatch was 64, 15, and 4%, respectively. Larvae hatching from eggs laid by adults fed lufenuron at concentrations of 0.025, 0.08, or 0.125 ppm did not differ significantly from the control. However, many larvae from the 0.08-ppm group and higher concentrations died during the 1st instar. Examination of these larvae revealed that they were dying from desiccation caused by bleeding from microscopic lesions in the cuticle or the inability to complete the molt to the next instar. Electron micrographs showed that lufenuron often disrupted formation of the endocuticle resulting in the deposition of an amorphous mass of randomly oriented chitin microfibrils. Other larvae formed normal endocuticle but were unable to digest the old endocuticle or produce new procuticle after apolysis. Failure of larvae to digest old cuticle or form new cuticle was caused by degeneration of the epidermal cells needed for the synthesis of molting fluid and chitin. 相似文献
100.
D de Silva A Osborne SA Simpson JC Dean A Seaton 《Canadian Metallurgical Quarterly》1998,53(2):149-50; discussion 148
A 64 year old woman presented with persistent and severe symptoms due to recurrent aspiration pneumonias associated with oesophageal reflux. She had had multiple miscarriages and her son at birth had widely spaced eyes (hypertelorism), hypospadias, bilateral undescended testes, and an imperforate anus. Her daughter has mild hypertelorism and her daughter's son had neonatal inspiratory stridor, hypospadias and hypertelorism, all features now recognised as typical of the Opitz oculo-genito-laryngeal syndrome. This syndrome is genetically heterogeneous with autosomal dominant (linked to chromosome 22q21) and X-linked (linked to Xp22) inheritance. This family's history and genetic linkage data are consistent with linkage to Xp22. The proband is a manifesting carrier of this syndrome; her history of recurrent aspiration is probably secondary to pharyngeal neuromuscular incoordination aggravating gastro-oesophageal reflux. Obtaining a family history gives a vital clue to the diagnosis of Opitz oculo-genito-laryngeal syndrome. It is also suggested that this condition should be included in the differential diagnosis of recurrent aspiration pneumonia. 相似文献