Advances in the Therapeutic Effects of Apoptotic Bodies on Systemic Diseases

Apoptosis plays an important role in development and in the maintenance of homeostasis. Apoptotic bodies (ApoBDs) are specifically generated from apoptotic cells and can contain a large variety of biological molecules, which are of great significance in intercellular communications and the regulation of phagocytes. Emerging evidence in recent years has shown that ApoBDs are essential for maintaining homeostasis, including systemic bone density and immune regulation as well as tissue regeneration. Moreover, studies have revealed the therapeutic effects of ApoBDs on systemic diseases, including cancer, atherosclerosis, diabetes, hepatic fibrosis, and wound healing, which can be used to treat potential targets. This review summarizes current research on the generation, application, and reconstruction of ApoBDs regarding their functions in cellular regulation and on systemic diseases, providing strong evidence and therapeutic strategies for further insights into related diseases.     

Wave-induced flow of pore fluid in a cracked porous solid containing penny-shaped inclusions

An aim of current study is to analyze the contribution of reflected longitudinal waves to wave-induced fluid flow(WIFF)in the cracked porous solid.Initially,we ...     

A near-optimum detector with reduced out-of band response fornarrowband signals

Reduced spectral response in adjacent spectral bins is very desirable for detectors since it gives capability to detect narrowband signals in the presence of unknown interference and colored noise. Conventionally, this is achieved by applying a smoothing window on the signal at the cost of detection performance. In this correspondence, a new method of detecting narrowband signals that uses a close approximation to the matched filter and the extrapolated input signal is proposed. The filter used has a frequency response that is very closely equal to that of the matched filter within a Doppler bin and nearly zero response outside it     

Generalized form of optimal teleportation witnesses

We propose a generalized form of optimal teleportation witness to demonstrate their importance in experimental detection of the larger set of entangled states useful for teleportation in higher dimensional systems. The interesting properties of our witness reveal that teleportation witness can be used to characterize mixed state entanglement using Schmidt numbers. Our results show that while every teleportation witness is also a entanglement witness, the converse is not true. Also, we show that a hermitian operator is a teleportation witness iff it is a decomposable entanglement witness. In addition, we analyze the practical significance of our study by decomposing our teleportation witness in terms of Pauli and Gell-Mann matrices, which are experimentally measurable quantities.     

Role of nanoscale AlN and InN for the microwave characteristics of AlGaN/(Al,In)N/GaN-based HEMT

A new AlGaN/GaN-based high electron mobility transistor (HEMT) is proposed and its micro-wave characteristics are discussed by introducing a nanoscale AlN or InN layer to study the potential improvement in their high frequency performance. The 2DEG transport mechanism including various sub-band calculations for both (Al,In) N-based HEMTs are also discussed in the paper. Apart from direct current characteristics of the proposed HEMT, various microwave parameters such as transconductance, unit current gain (h ₂₁ = 1) cut-off frequency (f _t ), high power-gain frequency (f _max). Masons available/stable gain and masons unilateral gain are also discussed for both devices to understand its suitable deployment in microwave frequency range.