Optimization of A-TIG process parameters using response surface methodology

In the present work, the influence of process parameters such as welding current (I), welding speed (S), and flux coating density (F) on different aspects of weld bead geometry for example depth of penetration (DOP), bead width (BW), depth to width ratio (D/W), and weld fusion zone area (WA) were investigated by using the central composite design (CCD). 9–12% Cr ferritic stainless steel (FSS) plates were welded using A-TIG welding. It was observed that all input variables have a direct influence on the DOP, BW, and D/W. However, flux coating density has no significant effect on WA. Mathematical models were generated from the obtained responses to predict the weld bead geometry. An optimized DOP, BW, D/W, and WA of 6.95?mm, 8.76?mm, 0.80, and 41.99?mm², respectively, were predicted at the welding current of 213.78 A, the welding speed of 96.22?mm/min, and the flux coating density of 1.99?mg/cm². Conformity test was done to check the practicability of the developed models. The conformity test results were in good agreement with the predicted values. Arc constriction and reversal in Marangoni convection were considered as major mechanisms for the deep and narrow weld bead during A-TIG welding.     

Chromatic aberrations of radial gradient-index lenses. I. Theory

Chromatic effects of radial gradient-index materials have been analyzed, and several important conclusions have been derived in terms of material dispersion data. The use of Buchdahl dispersion data, both for base glass materials and ion-exchange pairs, provides some simple relationships for chromatic aberration and helps in selecting suitable materials for producing achromatic radial gradient-index lenses.     

Does India need to harmonize the law of patent exhaustion and parallel imports?

The amendment of patent law of India in 2005 to fulfill her international obligation under the TRIPS Agreement (World Trade Organization Agreement on Trade Related Intellectual Property Rights) was an outcome of an attempt to balance the competing interests of several stakeholders, including indigenous pharmaceutical companies, multi-national pharmaceutical companies, non-governmental organizations and civil society groups concerned with access to affordable drugs. The adverse consequence of this delicate balancing is introduction of some provisions in the Act whose compatibility with the TRIPS Agreement is questionable, and which therefore are prone to litigations. Section 107A(b) of the amended patent law dealing with parallel imports is one such provision, which, if interpreted word for word could have significant connotations for the rights of a patent owner. This article aims to examine the inconsistencies intrinsic in Section 107A(b) and discusses the divergences in the Indian patent law associated with the doctrine of exhaustion and parallel imports. This article also proposes legal amendments with a view to eliminate inconsistencies intrinsic in the section and enlarge the ambit of the exhaustion principle conceptualized therein, while concurrently remaining compliant with the TRIPS Agreement.     

Solving single-product economic lot-sizing problem with non-increasing setup cost,constant capacity and convex inventory cost in O(N log N) time

This paper considers an economic lot sizing model with constant capacity, non-increasing setup cost, and convex inventory cost function. Algorithms with computational time of O(N×TD_N)have been developed for solving the model, where N is the number of planning periods and TD_N is the total demand. This study partially characterizes the optimal planning structure of the model. A new efficient algorithm with computational time of O(N log N) has also been developed based on the partial optimal structure. Moreover, computational study demonstrates that the new algorithm is efficient.     

Ascorbic acid imprinted polymer-modified graphite electrode: A diagnostic sensor for hypovitaminosis C at ultra trace ascorbic acid level

A new kind of molecularly imprinted polymer-modified graphite electrode was fabricated by “grafting-to” approach, incorporating sol–gel technique, for the detection of acute deficiency in serum ascorbic acid level (SAAL), manifesting hypovitaminosis C. The modified electrode exhibited ascorbic acid (AA) oxidation at less positive potential (0.0 V) than the earlier reported methods, resulting in a limit of detection as low as 6.13 ng mL⁻¹ (RSD = 1.2%, S/N = 3). The diffusion coefficient (1.096 × 10⁻⁵ cm² s⁻¹), rate constant (7.308 s⁻¹), and Gibb's free energy change (−12.59 kJ mol⁻¹) due to analyte adsorption, were also calculated to explore the kinetics of AA oxidation. The proposed sensor was found to enhance sensitivity substantially so as to detect ultra trace level of AA in the presence of other biologically important compounds (dopamine, uric acid, etc.), without any cross interference and matrix complications from biological fluids and pharmaceutical samples.