多功能Pt-Ce6纳米平台作为过氧化氢纳米酶和NIR-Ⅱ光热剂用于增强PDT/PTT肿瘤治疗

实体肿瘤的缺氧严重影响着基于氧气的光动力疗法(PDT)的效果.另外,单一治疗模式通常难以达到满意的治疗效果.为此,我们设计合成了一种多功能纳米复合材料Pt-Ce6用于克服肿瘤乏氧,实现PDT/PTT协同治疗.在该体系中,我们使用多孔Pt纳米粒子作为过氧化氢纳米酶、近红外二区(NIR-Ⅱ)光热转换剂和光敏剂二氢卟吩e6(...     

Improved diagnosis using enhanced fault dominance

Defect diagnosis can benefit from fault dominance relations to reduce the set of defect candidate sites. This paper presents new fault dominance collapsing operators that further reduce the set of candidates considered during the initial phase of diagnosis. In contrast to existing dominance-based methods which operate on pairs of faults, the proposed method operates on sets of faults. Fault-related entities are generated to guide the diagnosis process. The proposed collapsing operators can be used to accelerate effect-cause diagnosis. Experimental results demonstrate that the proposed method achieves a higher collapsing ratio than existing methods.     

WIPO Panels’ interpretation of the Uniform Dispute Resolution Policy (UDRP) three-prong test

The Uniform Dispute Resolution Policy (UDRP) is a unique process that resolves domain name disputes effectively and inexpensively. This paper, through an analysis of the UDRP three-prong test, revealed that even though the UDRP affords a great degree of discretion to the WIPO Panels deciding any given case, there is some consistency and predictability inherent in the UDRP process.     

Europe should stop taxing innovation

After nearly 48 years of failure to create the EU patent, language issues and the design of a centralised patent-litigation court still dominate headlines. But behind these issues there are high financial stakes and control power to play for. The recent EU Council deal on an ‘enhanced’ European patent system does not solve the above problems, and has not eliminated lingering governance issues. The risk for Europe is that a final patent agreement might be reached that does not cure the system of its major ills, and thus does not bring about any significant improvement for those that need it most: entrepreneurs and innovative companies starting out on the innovation process. The creation of an effective single EU patent requires (i) English-only post-grant translation, (ii) the end of nationally granted patents, (iii) phasing-out of the current ‘European patent’, (iv) lower fees for young innovative companies, and (v) a radical shake-up of the governance of the European Patent Office.     

Choice of a pertinent color space for color texture characterization using parametric spectral analysis

This article presents a comparison of different color spaces including RGB, IHLS and L?a*b* for color texture characterization. This comparison is based on the fusion of the independent spatial structure and color feature cues. In IHLS and L*a*b*, two channel complex color images are created from the luminance and the chrominance values. For such images, two dimensional complex multichannel linear prediction models are used to perform parametric power spectrum estimation and the structure feature cues are computed from this estimated power spectrum. Quantitative comparison of auto spectra of luminance and combined chrominance channels for different color spaces is done. This comparison is based on the degree of decorrelation between luminance and chrominance information provided by different color space transformations. Three dimensional histograms are used as color feature cues. Then, to classify color textures, Kullback-Leibler divergence based symmetric distance measures are calculated for pure color, luminance structure and chrominance structure feature cues. Individual as well as combined effect of information from all feature cues on classification results is then compared for different color spaces and different color texture data sets. The proposed color texture classification method performs better than the state of the art methods in certain cases. The L*a*b* color space gives us a better characterization of the chrominance spatial structure as well as the overall spatial structure for all of the chosen data sets. Experimental results on pixel classification of color textures are also presented and discussed.     

A fast parallel (23, 12, 7) QR decoder based on syndrome-weight determination

In this paper, a time-area efficient hardware decoder of the (23, 12, 7) quadratic residue code, or Golay code, is presented. The key feature of this proposed algorithm lies in fast determination of error positions through the analysis on the weight of syndromes without large operations in finite fields. Comparing with the algorithm using one syndrome, the proposed algorithm is more suitable for the parallel hardware design by using two syndromes. Based on an Altera Cyclone II field-programmable gate array (FPGA) device (EP2C35F484C6), the area cost and the time delay of the complete system are reduced by up to 86.4% and 22.5%, respectively. Using the Taiwan Semiconductor Manufacturing Company (TSMC) 0.18-μm complementary metal-oxide-semiconductor (CMOS) standard cell library, the proposed decoder is 91.8% smaller and 8.3% faster.     

Additive noise removal using a novel fuzzy-based filter

The paper proposes a new fuzzy-based two-step filter for restoring images corrupted with additive noise. The goal of the first step is to compute the difference between the central pixel and its neighborhood in a selected window and to compute a fuzzy membership degree for each difference value using a Gaussian membership function. Computed fuzzy membership values are appropriately utilized as weights for each pixel and then computes the weighted average representing the modified value for the current central pixel. The second step is used as an augmented step to the first one and its goal is to improve the result obtained in the first step by reducing the noise in the color component differences without destroying the fine details of the image. The experimental analysis shows that the proposed method gives better results compared to existing advanced filters for additive noise reduction. Both visual, quantitative and qualitative analysis have been done to prove the efficiency and effectiveness of the proposed method.