Results of a 90-day toxicity study on 1,2,3- and 1,1,2-trichloropropane administered via the drinking water

Trichloropropanes have been identified as environmental contaminants in sediments of the Great Lakes region of North America. Since these chemicals had the potential to find their way into drinking water, a 90-day feeding study was carried out in order to determine their subchronic toxicity. Groups of 10 male and 10 female weanling Sprague-Dawley rats were supplied drinking water ad libitum, containing 1,2,3- or 1,1,2-trichloropropane at concentrations of 1, 10, 100 or 1000 mg/L for 13 weeks. Emulphor (0.5%) was used to solubilize the chemicals. At the end of the study, the animals were killed and examined for gross and microscopic changes. Heart, liver, brain, kidney and spleen were excised and weighed. Blood was collected and subjected to a comprehensive hematological analysis. Serum was collected and profiled for changes in 12 biochemical parameters and a portion of liver was used to determine mixed function oxidase activity. Although three animals died during the study, their deaths could not be related to treatment. Decreased growth rate was observed in both sexes of the group receiving 1000 mg/L 1,2,3-trichloropropane. There was an increase in liver, kidney and brain weights (relative to body weight) in rats of both sexes fed 1000 mg/L 1,2,3-trichloropropane. Fatty livers were observed in some of the treated animals but a clear dose-relationship was not evident. An elevation in serum cholesterol was observed in female rats fed the highest dose of 1,2,3-trichloropropane. This chemical also induced hepatic aminopyrine demethylase and aniline hydroxylase activities in male rats at the highest dose. Administration of both isomers produced only mild histological changes in the liver, thyroid and kidney of rats at the highest dose. The changes in the liver consisted of an increase in cytoplasmic eosinophilia in the periportal area together with vesiculation of biliary epithelial nuclei. Morphological changes were characterized by increased anisokaryosis in the proximal epithelium and occasional pyknosis associated with the accumulation of large eosinophilic inclusions. Changes in the thyroid consisted of a mild reduction in follicular size associated with an increased epithelial height. In general, these changes were more severe in the males than females, but were still mild overall. It was concluded that the no-effect level for both chemicals was 100 mg/L (15–20 mg/kg bw/day) and based on effects on growth rate and other changes, the 1,2,3- isomer was judged to be slightly more toxic than the 1,1,2- isomer.     

Growth temperature dependence of low-noise MESFET in molecular-beam epitaxy

The substrate growth temperature dependence of electrical properties for a low-noise MESFET fabricated on MBE-grown material has been demonstrated. The optimum noise figure and its associated gain were attributed to the higher epilayer quality and mobility at a growth temperature of 650°C between temperatures of 550°C and 700°C.     

广义Foster定理

利用Ｍａｘｗｅｌｌ方程组导出了适用于有耗网络的广义Ｆｏｓｔｅｒ定理，得到了一些有关电抗斜率以及Ｑ值的有用公式及结论。     

One-stage sternal stenting with homograft bone after cardiac operation in pediatric patients

Low cardiac output after open heart operations in neonates and infants carries a high mortality. Delayed sternal closure may be life-saving but may prolong hospital stay and increase costs. To circumvent these issues, we shaped homograft bone and interposed it between the sternal edges to allow primary wound closure in 2 pediatric patients. Midterm results are satisfactory.     

Synthesis and Properties of the Bi-Based Superconducting Powder Prepared by the Pechini Process

Bi-based superconductors are of great interest in high-temperature superconductors. We describe what is believed to be the first synthesis of these materials using the Pechini process, a low-temperature synthetic method that often yields inorganic oxide of excellent phase purity and well-controlled stoichiometry. Using this process, it has been possible to synthesize phase-pure Bi-2223 phase by calcining the appropriate polymeric precursors in air at 800°C for several hours. The superconductivity studies show that the Pechini-synthesized materials appear to offer high-quality performance.     

A knowledge-based approach for retrieving images by content

A knowledge based approach is introduced for retrieving images by content. It supports the answering of conceptual image queries involving similar-to predicates, spatial semantic operators, and references to conceptual terms. Interested objects in the images are represented by contours segmented from images. Image content such as shapes and spatial relationships are derived from object contours according to domain specific image knowledge. A three layered model is proposed for integrating image representations, extracted image features, and image semantics. With such a model, images can be retrieved based on the features and content specified in the queries. The knowledge based query processing is based on a query relaxation technique. The image features are classified by an automatic clustering algorithm and represented by Type Abstraction Hierarchies (TAHs) for knowledge based query processing. Since the features selected for TAH generation are based on context and user profile, and the TAHs can be generated automatically by a clustering algorithm from the feature database, our proposed image retrieval approach is scalable and context sensitive. The performance of the proposed knowledge based query processing is also discussed     

火焰动画快速模拟的新方法

针对火焰动画难以快速建模和绘制的问题,提出了完全利用GPU过程化生成火焰动画的高效算法。先用建模工具在预处理阶段构建一个由平面正方形组成的三维模型,在绘制阶段通过GPU编程对这些方形进行Billboard方式的变换,并用一些简单公式对他们的运动方式、大小和颜色来用过程化方式进行控制,最后通过alpha混合得到最终结果。算法完全在GPU里实现,能满足实时的绘制要求。     

结构正则化多视图非负矩阵分解

现存非负矩阵分解（non-negative matrix factorization,NMF）研究多考虑单一视图分解数据,忽略了数据信息的全面性。此外,NMF限制其获取数据的内在几何结构。针对以上问题,提出一个结构正则化多视图非负矩阵分解算法（structure regularized multi-view nonnegative matrix factorization,SRMNMF）。首先,通过主成分分析来对数据进行全局结构的判别式学习;其次,利用流形学习来捕获数据的局部结构;然后,通过利用多视图数据的多样性和差异性来学习表征。模型提升了算法聚类的整体性能,更加有效地挖掘数据的结构信息。此外,采用高效的交替迭代算法优化目标函数得到最优的因子矩阵。在六个数据集上与现存的代表性方法比较,所提出的SRMNMF的准确率、NMI和Purity分别最大提高4.4%、6.1%和4.05%。     

A deep multi-source adaptation transfer network for cross-subject electroencephalogram emotion recognition

Neural Computing and Applications - In real-world application of affective brain–computer interface (aBCI), individual differences across subjects and non-stationary characteristics of...     

基于参数空间法的飞行器再入控制研究

针对空天飞行器再入段环境变化剧烈、气动参数变化范围大的特点,采用参数空间方法来设计其控制系统;首先建立飞行器控制系统的数学模型,鉴于飞行器再入过程中对攻角有着严格的要求,设计了以攻角反馈为被控信号的三回路自动驾驶仪结构,然后根据参数空间方法求出对应的控制器参数,最后基于Matlab/Simulink的非线性仿真表明,所设计的控制系统在大气密度偏差±30%、气动力/力矩系数各偏差±20%的组合偏差情况下仍具有较好的鲁棒稳定性和跟踪性能。