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121.
Individuals' reactions to their performance appraisal interviews were examined in two analyses of managers who appraised their subordinates. We hypothesized that managers' reactions toward their own appraisal interview would be influenced by both supervisor satisfaction and favorability of the feedback they received. We also hypothesized that managers' reactions would be affected by system satisfaction (i.e., their attitudes toward the system's ability to document the performance of their subordinates). Questionnaires were administered to managers in eight colleges and universities in one state system. Results indicated that managers distinguished between satisfaction with their own appraisal and its value in improving performance. Appraisal satisfaction was predicted by supervisor satisfaction and the recollection of their rating, but not system satisfaction. In a follow-up analysis, results were confirmed with managers in the original sample. The appraisal's improvement value was associated with supervisor satisfaction, and inversely related with performance rating. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
122.
Published results for window glass panel failures were analyzed by using finite-difference methods to determine the stress states at the fracture origins. Although the state of stress was often complex, it was found that the maximum principal tensile stress at the fracture origin correlated with the fracture mirror. size. Fracture mirror constants were calculated and found to agree closely with published values. 相似文献
123.
Women are still regarded less than seriously by most major financial institutions, particularly when it comes to insurance. 相似文献
124.
Dorothy M. Morr 《Microscopy research and technique》1991,17(2):200-211
The Golgi apparatus response to pathological disorders is predominantly as an intermediary component of membrane biogenesis where it is involved in processing, sorting and secretion of materials via secretory granules, and in the formation of lysosomes. A common initial response of the Golgi apparatus to any stress is an alteration or cessation of secretory activity. In the transformed cell, the Golgi apparatus is altered both morphologically and biochemically, suggesting a shift from a secretory to a membrane-generating mode of functioning. However, since fewer or less well-developed Golgi apparatus are frequently found in transformed cells, analytical methods of membrane isolation developed for normal tissues may not always yield equivalent results when applied to tumors. Cell surface alterations characteristic of malignant cells may result from modifications occurring at the level of the Golgi apparatus. Some lysosomal dysfunctions may result from underglycosylation of acid hydrolases by the Golgi apparatus. The use of cell-free systems between endoplasmic reticulum and Golgi apparatus or within Golgi apparatus cisterane is providing a new approach to the elucidation of the role of the Golgi apparatus in normal as well as pathological states. 相似文献
125.
Ginsberg Dorothy; Hall Sharon M.; Reus Victor I.; Mu?oz Ricardo F. 《Canadian Metallurgical Quarterly》1995,3(4):389
The history of major depressive disorder (MDD), mood at baseline and during quitting, and abstinence at 2 and 52 weeks in 62 smoking treatment patients were examined. Of these participants, 44% were positive for a history of MDD. Depressive history participants had more anger and less vigor at baseline and greater increases in anger and depression during quitting than those without a history. There were significant interactive effects of baseline mood by depression history in predicting abstinence at Week 2 but not at Week 52. Participants with a depression history and who reported greater depression, fatigue, and anger at baseline had lower 2-week abstinence rates than those without a depression history, although not significantly. Participants with a depression history and who reported less depression, fatigue, and anger at baseline had higher 2-week abstinence rates than those without a depression history, although not significantly. Baseline-to-quitting increases in depression were negatively related to 2-week abstinence. Mood during quitting was not significantly related to abstinence at either week. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
126.
T. J. Garosshen T. D. Tillman G. P. McCarthy 《Metallurgical and Materials Transactions A》1987,18(1):69-77
The boron and carbon levels of a P/M nickel base superalloy were systematically varied in order to determine the mechanisms
by which these elements strengthen the alloy, and their optimum concentration. Carbon levels were reduced to 20 ppm while
the boron level was varied from 0.02 to 0.10 wt pct. Carbon levels of 0.002 and 0.05 wt pct were also studied, while maintaining
a boron concentration of 0.02 wt pct. Zirconium levels were maintained at 0.06 wt pct. The resulting alloys were subjected
to identical heat treatments and examinedvia SEM, TEM, and STEM microscopy. The alloys were also subjected to tensile, creep, stress-rupture, and fatigue crack growth
tests. Results show that both carbon and boron have a strong influence on the formation of grain boundary precipitates, as
expected. Carbon was present as the MC and M23C6 type carbides, while boron combined to form an intergranular M3B2 boride. Boron and zirconium were observed to be critical to the alloys' mechanical properties, although boron levels above
the solubility limit resulted in no further improvement or debit in strength. Carbon additions resulted in no improvement
in properties, indicating the feasibility of a carbon-free P/M superalloy. The role of the minor element additions is discussed
in terms of both microstructural features and related strengthening mechanisms. 相似文献
127.
Fas is expressed constitutively in colonic epithelial cells and is also expressed in colon carcinomas and in cultured colon carcinoma cell lines. However, the potential role of Fas signaling in mediating apoptosis in cells of this type remains unknown. We have developed human colon carcinoma cell models deficient in thymidylate synthase that demonstrate acute (TS- cells) or delayed (Thy4 cells) apoptosis following DNA damage induced by thymineless stress. Complete protection of cells from acute apoptosis and prolongation of delayed apoptosis was obtained following exposure to the NOK-1 monoclonal antibody (inhibitory to Fas signaling) during the period of dThd deprivation. These results suggested that apoptosis induced by thymineless stress was regulated by autocrine signaling via Fas-FasL interactions. Fas expression was high in both TS- and Thy4 cells. However, FasL, undetectable in synchronous cultures, was up-regulated in TS- cells at 48 hr, when cells were undergoing acute apoptosis, and in Thy4 cells at 96 hr, correlating with the delayed onset of thymineless death. FasL expression also correlated with acute apoptosis induced in parental GC3/cl cells, commencing at 48 hr, following thymidylate synthase inhibition by 5-fluorouracil/leucovorin exposure. Fas-mediated apoptosis induced by the cytotoxic anti-Fas monoclonal antibody CH-11 was inhibited following adenoviral delivery of a Bcl-2 cDNA, and Bcl-2 also protected cells from acute apoptosis induced by dThd deprivation. Taken together, these data demonstrate a functional Fas system in these cultured colon carcinoma cell models, and they demonstrate that Fas-FasL interactions can link DNA damage induced by thymineless stress to the apoptotic machinery of colon carcinoma cells. 相似文献
128.
A stochastic model is developed to quantify the reliability of human performance. The model provides closed-form mathematical expressions into which multiple factors affecting the reliability of man-machine system can be incorporated. Three elements of man-machine systems are combined to form the framework for modeling: random task arrivals, transient human performance characteristics (detection of task arrivals, performance accuracy, performance time, etc.), and operational requirements of the system. Simulation and numerical models that could be developed within this framework are indicated 相似文献
129.
This study examined the contributions of physical and sensorimotor development to manipulation in capuchins (Cebus apella) from birth to 2 years. Between months 1–6 and 7–12, manipulation increased significantly in frequency, in the proportion that was vigorous or required fine motor control, and in the proportion directed at portable objects. Fine motor control, moving objects in relation to the body, and stamina are largely in place by 12 months, after which little changed. All elements of the manipulative repertoire have appeared, and vigorous and dexterous activities have peaked before fully independent foraging. Emergence of permanent dentition and achievement of approximately half of adult body size accompany the attainment of fully independent foraging at 15 months. Thereafter, increasing strength and specific knowledge probably contribute more to changing foraging competence in young capuchins than do stamina and sensorimotor development. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
130.
ABSTRACTModern organizations face significant information security threats, to which they respond with various managerial techniques. It is widely believed that “one size does not fit all” for achieving employee information security policy compliance; nevertheless, it is yet to be determined which techniques work best to different organizational employees. We further this research stream by finding that different levels of users might be effectively motivated by different types of coercive and empowering techniques that are suitable to their level and position in the organizational chart. Our results suggest that participation in the ISP decision-making process might prove to be a more effective approach to motivate lower-level employees toward compliance and that enhancing the meaningfulness of policy compliance could be the preferred method among higher levels of management. Members within each level of the organization can be effectively influenced to comply with ISPs when such strategies are customized for their level. 相似文献