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111.
Cássia A. Glasser Marta M. D. C. Vila Júlio C. Pereira Marco V. Chaud José M. Oliveira Júnior Matthieu Tubino 《Drug development and industrial pharmacy》2016,42(12):1990-2000
The aqueous-core enclosed in lipid nanoballoons integrating multiple emulsions of the type water-in-oil-in-water mimic, at least in theory, the environment within viable cells, thus being suitable for housing hydrophilic protein entities such as bioactive proteins, peptides and bacteriophage particles. This study reports a complete physicochemical characterization of optimized biomimetic aqueous-core lipid nanoballoons housing hydrophilic (BSA) protein entities, evolved from a statistical 23×31 factorial design study (three variables at two levels and one variable at three levels) that was the subject of the first paper of a series of three, aiming at complete stabilization of the three-dimensional structure of protein entities attempted via housing the said molecular entities within biomimetic aqueous-core lipid nanoballoons integrating a multiple (W/O/W) emulsion. The statistical factorial design followed led to the production of an optimum W/O/W multiple emulsion possessing quite homogeneous particles with an average hydrodynamic size of (186.2?±?2.6) nm and average Zeta potential of (?36.5?±?0.9) mV, and exhibiting a polydispersity index of 0.206?±?0.014. Additionally, the results obtained for the diffusion coefficient of the lipid nanoballoons integrating the optimized W/O/W multiple emulsion were comparable and of the same order of magnitude (10?12 m2 s?1) as those published by other authors since, typically, diffusion coefficients for molecules range from 10?10 to 10?7 m2 s?1, but diffusion coefficients for nanoparticles are typically of the order of magnitude of 10?12 m2 s?1. 相似文献
112.
Jun Pan Li Na Quan Yongbiao Zhao Wei Peng Banavoth Murali Smritakshi P. Sarmah Mingjian Yuan Lutfan Sinatra Noktan M. Alyami Jiakai Liu Emre Yassitepe Zhenyu Yang Oleksandr Voznyy Riccardo Comin Mohamed N. Hedhili Omar F. Mohammed Zheng Hong Lu Dong Ha Kim Edward H. Sargent Osman M. Bakr 《Advanced materials (Deerfield Beach, Fla.)》2016,28(39):8718-8725
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Achieving stability at the site of femoral neck fracture is an important factor for callus formation in the post-operative period. However, measuring interfragmentary movement in vivo is not currently possible as telemetric screws have not been manufactured for surgical use. Understanding how the implantation of the screws can affect the stability of the fracture allows the surgeon to tailor the procedure to the patient and produce the best possible outcome. Two techniques have been developed that measure interfragmentary movement between fractured surfaces. The first was a FEA model of the proximal femur with screws represented by nodal links. Movement was quantified by the amount of relative motion occurring between paired nodes either side of the fracture. The second was a mechanical compression test of a composite femur that allowed the motion analysis of paired markers on the external surface of the femur. Movement was digitised with markers selected and displacements calculated by transforming the global coordinate system to a local system relative to the fracture plane. 相似文献
116.
Linda A. Jackson Alexander von EyeHiram E. Fitzgerald Edward A. WittYong Zhao 《Computers in human behavior》2011,27(1):599-604
In this research we examined the prediction of children’s body mass index (BMI), body weight, academic performance, social self-esteem and overall self-esteem from their IT (information technology) use, specifically, their Internet use, cell phone use and videogame playing, after controlling for the effects of gender, race, age and household income on these measures. Participants were 482 children whose average age was 12 years old. One-third was African American and two-thirds were Caucasian American. Results indicated that IT use did not predict BMI or body weight, contrary to one previous survey and the widespread belief that screen time is responsible for the obesity epidemic among our nation’s children. Instead, BMI and body weight were higher for African Americans, older children and children from lower income households. The sole and strong positive predictor of visual-spatial skills was videogame playing, which also predicted lower grade point averages (GPAs). Gender and Internet use predicted standardized test scores in reading skills. Females and children who used the Internet more had better reading skills than did males and children who used the Internet less, respectively. Implications of these findings for future research on the benefits and liabilities of IT use are discussed. 相似文献
117.
The objective of the current research is to model trends in video game playing, overall computer use, and communication technology use in a longitudinal sample of youths, aged 11-16 over a 3-year interval. In addition, individual difference characteristics that may be predictive of these trends were included, namely, socio-demographic characteristics (gender, ethnicity, and parental income) and personality characteristics (self-esteem, the Big Five personality factors). Findings suggested that youth increased their overall computer and communication technology use but decreased their videogame playing over time. Many individual differences predicted mean levels of these technologies with fewer predicting slopes. Conclusions, implications, and limitations are discussed. 相似文献
118.
Camera distortion self-calibration using the plumb-line constraint and minimal Hough entropy 总被引:1,自引:0,他引:1
In this paper, we present a simple and robust method for self-correction of camera distortion using single images of scenes
which contain straight lines. Since the most common distortion can be modelled as radial distortion, we illustrate the method
using the Harris radial distortion model, but the method is applicable to any distortion model. The method is based on transforming
the edgels of the distorted image to a 1-D angular Hough space, and optimizing the distortion correction parameters which
minimize the entropy of the corresponding normalized histogram. Properly corrected imagery will have fewer curved lines, and
therefore less spread in Hough space. Since the method does not rely on any image structure beyond the existence of edgels
sharing some common orientations and does not use edge fitting, it is applicable to a wide variety of image types. For instance,
it can be applied equally well to images of texture with weak but dominant orientations, or images with strong vanishing points.
Finally, the method is performed on both synthetic and real data revealing that it is particularly robust to noise. 相似文献
119.
Marta Alberti Joaquim Ciurana Ciro A. Rodríguez Tugrul Özel 《Journal of Intelligent Manufacturing》2011,22(2):263-277
Economic globalization, together with heightened market competition and increasingly short product life cycles are motivating
companies to use advanced manufacturing technologies. Use of high speed machining is increasingly widespread; however, as
the technology is relatively new, it lacks a deep-rooted knowledge base which would facilitate implementation. One of the
most frequent problems facing companies wishing to adopt this technology is selecting the most appropriate machine tool for
the product in question and own enterprise characteristics. This paper presents a decision support system for high speed milling
machine tool selection based on machine characteristics and performance tests. Profile machining tests are designed and conducted
in participating machining centers. The decision support system is based on product dimension accuracy, process parameters
such as feed rate and interpolation scheme used by CNC and machine characteristics such as machine accuracy and cost. Experimental
data for process error and cycle operation time are obtained from profile machining tests with different geometrical feature
zones that are often used in manufacturing of discrete parts or die/moulds. All those input parameters have direct impact
on productivity and manufacturing cost. Artificial neural network models are utilized for decision support system with reasonable
prediction capability. 相似文献
120.
José Luis Crespo Marta Zorrilla Pilar Bernardos Eduardo Mora 《The Visual computer》2009,25(4):309-323
The objective of this paper is to present an overall approach to forecasting the future position of the moving objects of
an image sequence after processing the images previous to it. The proposed method makes use of classical techniques such as
optical flow to extract objects’ trajectories and velocities, and autoregressive algorithms to build the predictive model.
Our method can be used in a variety of applications, where videos with stationary cameras are used, moving objects are not
deformed and change their position with time. One of these applications is traffic control, which is used in this paper as
a case study with different meteorological conditions to compare with.
相似文献
Marta Zorrilla (Corresponding author)Email: |