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41.
Ehud Ben-Sabar Bruce Caswell 《International journal for numerical methods in engineering》1979,14(4):545-565
A finite element simulation of the equations of momentum and energy transport in fluids has been implemented with triangular elements. An attempt is made to single out the reasons for numerical instabilities reported by other investigators for convection–diffusion transport operations in fluid mechanics when the ratio of the convective to the diffusive terms, measured by the Reynolds and Peclét numbers, is of the order of a hundred. To this end, the equations are solved for several problems to permit a direct comparison with results of other formulations. It is shown that the appearance of instability can be delayed by a proper choice of boundary conditions, and its intensity can be reduced through the use of triangular finite elements. Results agree very well with theoretical solutions for particular test problems including flows with large convection effects, large dissipation effects and fluids with temperature dependent properties. 相似文献
42.
We examined the relations between coping, locus of control, and social support and combat-related posttraumatic stress disorder (PTSD). The sample consisted of 262 Israeli soldiers who suffered a combat stress reaction episode during the 1982 Lebanon war and were followed 2 and 3 years after their participation in combat. Cross-sectional analyses revealed significant relations between locus of control, coping, and social support and PTSD at the two points of assessment. Changes in PTSD from Time 1 to Time 2 were also associated with changes in coping. We discuss theoretical and methodological implications of the findings. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
43.
A general paradigm for solving resource allocation, time-tabling, and scheduling problems is presented. The paradigm is based on an expert system approach, which looks for a feasible solution that satisfies the problem's real-life constraints. The new paradigm includes generic concepts for resources, activities, constraints, and allocations. The general control strategy of the new paradigm is suitable for a large family of resource allocation and time-tabling problems. This control strategy includes three parts that deal with allocation, constraint checking, and changes to allocations.
The proposed paradigm was tested on three real-world problems: crew assignment to air force missions, class scheduling for a university department, and time-tabling of final examinations for the faculty of natural sciences. All cases were solved well in a few minutes of central processing unit time, by Prolog-based systems that implemented the proposed paradigm. These case studies are described in the paper in some detail, and an overall evaluation of the methodology is given. 相似文献
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The fabrication and notably improved performance of composite electrodes based on modified self-assembled diphenylalanine peptide nanotubes is described. Peptide nanotubes were attached to gold electrodes, and we studied the resulting electrochemical behavior using cyclic voltammetry and chronoamperometry. The peptide nanotube-based electrodes demonstrated a direct and unmediated response to hydrogen peroxide and NADH at a potential of +0.4 V (vs SCE). This biosensor enables a sensitive determination of glucose by monitoring the hydrogen peroxide produced by an enzymatic reaction between the glucose oxidase attached to the peptide nanotubes and glucose. In addition, the marked electrocatalytic activity toward NADH enabled a sensitive detection of ethanol using ethanol dehydrogenase and NAD+. The peptide nanotube-based amperometric biosensor provides a potential new tool for sensitive biosensors and biomolecular diagnostics. 相似文献
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Joseph O'Donnell Pierre-André Cazade Sarah Guerin Ahmed Djeghader Ehtsham Ul Haq Kai Tao Ehud Gazit Eiichi Fukada Christophe Silien Tewfik Soulimane Damien Thompson Syed A. M. Tofail 《Advanced functional materials》2021,31(28):2100884
Controlling the electromechanical response of piezoelectric biological structures including tissues, peptides, and amino acids provides new applications for biocompatible, sustainable materials in electronics and medicine. Here, the piezoelectric effect is revealed in another class of biological materials, with robust longitudinal and shear piezoelectricity measured in single crystals of the transmembrane protein ba3 cytochrome c oxidase from Thermus thermophilus. The experimental findings from piezoresponse force microscopy are substantiated using a range of control measurements and molecular models. The observed longitudinal and shear piezoelectric responses of ≈ 2 and 8 pm V−1, respectively, are comparable to or exceed the performance of commonly used inorganic piezoelectric materials including quartz, aluminum nitride, and zinc oxide. This suggests that transmembrane proteins may provide, in addition to physiological energy transduction, technologically useful piezoelectric material derived entirely from nature. Membrane proteins could extend the range of rationally designed biopiezoelectric materials far beyond the minimalistic peptide motifs currently used in miniaturized energy harvesters, and the finding of robust piezoelectric response in a transmembrane protein also raises fundamental questions regarding the molecular evolution, activation, and role of regulatory proteins in the cellular nanomachinery, indicating that piezoelectricity might be important for fundamental physiological processes. 相似文献
49.
Kai Tao Wen Hu Bin Xue Drahomir Chovan Noam Brown Linda J. W. Shimon Oguzhan Maraba Yi Cao Syed A. M. Tofail Damien Thompson Junbai Li Rusen Yang Ehud Gazit 《Advanced materials (Deerfield Beach, Fla.)》2019,31(12)
Peptide assemblies are ideal components for eco‐friendly optoelectronic energy harvesting devices due to their intrinsic biocompatibility, ease of fabrication, and flexible functionalization. However, to date, their practical applications have been limited due to the difficulty in obtaining stable, high‐performance devices. Here, it is shown that the tryptophan‐based simplest peptide cyclo‐glycine‐tryptophan (cyclo‐GW) forms mechanically robust (elastic modulus up to 24.0 GPa) and thermally stable up to 370 °C monoclinic crystals, due to a supramolecular packing combining dense parallel β‐sheet hydrogen bonding and herringbone edge‐to‐face aromatic interactions. The directional and extensive driving forces further confer unique optical properties, including aggregation‐induced blue emission and unusual stable photoluminescence. Moreover, the crystals produce a high and sustained open‐circuit voltage (1.2 V) due to a high piezoelectric coefficient of 14.1 pC N?1. These findings demonstrate the feasibility of utilizing self‐assembling peptides for fabrication of biointegrated microdevices that combine high structural stability, tailored optoelectronics, and significant energy harvesting properties. 相似文献
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