An Operator Approach to Tangent Vector Field Processing

In this paper, we introduce a novel coordinate‐free method for manipulating and analyzing vector fields on discrete surfaces. Unlike the commonly used representations of a vector field as an assignment of vectors to the faces of the mesh, or as real values on edges, we argue that vector fields can also be naturally viewed as operators whose domain and range are functions defined on the mesh. Although this point of view is common in differential geometry it has so far not been adopted in geometry processing applications. We recall the theoretical properties of vector fields represented as operators, and show that composition of vector fields with other functional operators is natural in this setup. This leads to the characterization of vector field properties through commutativity with other operators such as the Laplace‐Beltrami and symmetry operators, as well as to a straight‐forward definition of differential properties such as the Lie derivative. Finally, we demonstrate a range of applications, such as Killing vector field design, symmetric vector field estimation and joint design on multiple surfaces.     

A method for the remote sensing identification of uncontrolled landfills: formulation and validation

The identification of uncontrolled landfills is a central environmental problem in all developed and developing countries, where several illegal waste deposits exist as a result of rapid industrial growth over the past century. Remote sensing can potentially provide crucial information for the identification of contaminated sites, but surprisingly there is a marked lack of rigorously validated approaches. In this paper we introduce and validate a method that uses remotely sensed information and a geographic information system (GIS) to identify unknown landfills over large areas. The method is applied to a study area located in NE Italy (part of the Venice lagoon watershed) using IKONOS satellite data. Soil contamination effects on the radiometric properties of vegetation, calibrated using spectral signatures of stressed vegetation from known illegal landfill sites, were used to define numerous candidate sites that are most likely to host waste materials. Distributed geographical information, such as the position of the road network, the population density, and historical aerial photographs, have then been used to select the most likely contaminated sites among the candidates identified through remote sensing. The importance of the integration of GIS and remote sensing is highlighted and represents a key instrument for environmental management and for the spatially distributed characterization of possible uncontrolled landfill sites.     

Synthesis and characterization of new poly(ethylene glycol)bisphosphonate vinylic monomer and non-fluorescent and NIR-fluorescent bisphosphonate micrometer-sized particles

Bisphosphonates (BPs) are non-hydrolysable pyrophosphate analogs with high affinity to hydroxyapatite (HAP, the main inorganic ingredient in bones) and are mainly used for bone diseases treatments.A new stable PEG-BP monomer and particles have been prepared for enhanced long term bone-targeted imaging and therapy applications. The new formed BP particles possess dual functionalities: chelation to the bone mineral, HAP, through the BP groups and covalent attachment of a dye or drug through primary amine groups.The BP particles showed no cytotoxic effect on human osteosarcoma cell lines and minor toxicity on mouse macrophage cells, indicating that these BP particles are good candidates for in vivo testing. The BP monomer and particles exhibited inhibition of HAP formation and dissolution, similar to a commercial Alendronate. Near IR (NIR) fluorescent BP particles were obtained by conjugation of Cy7-NHS ester to the primary amine groups of the BP particles.     

On the Effective Deployment of Functional Formal Verification

We examine IBM's exploitation of formal verification using RuleBase—a formal verification tool developed by the IBM Haifa Research Laboratory. The goal of the paper is methodological. We identify an integrated methodology for the deployment of formal verification which involves three complementary modes: architectural verification, block-level verification, and design exploration.     

Redundancy gains for visual search after complete commissurotomy.

Redundant-targets effects (RTE) for visual search were investigated in 2 commissurotomy patients (L.B., N.G.). L.B., who showed no evidence of visual interhemispheric transfer, exhibited a paradoxical enhancement of the redundancy gain in the bilateral compared with the within-hemifield redundant-targets conditions, whereas N.G., who showed evidence of interhemispheric transfer of visual information, exhibited no enhancement of the bilateral redundancy gain. When only uncrossed responses were considered, both bilateral and within-field RTE were evident only when attentional demands were high. Bilateral redundant targets led to stronger gains, some indicative of coactivation, in the slower response hand. The authors suggest that the enhancement of the bilateral RTE comes about by neural coactivation, which is especially pronounced when the slower hemisphere elicits the response. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

The influence of the in-plane warping on the behavior of thin-walled beams

The paper presents a theoretical study of the importance of the in-plane deformation on the structural behavior of thin-walled isotropic and composite beams which are subjected to bending and torsional moments. To separate the effects of the out-of-plane warping and the in-plane warping, the overall solution methodology is based on a generic combination of two complementary “inner” and “outer” solutions. The inner model is based on numerical optimization tools which are employed to determine the in-plane deformation that will ensure a stationary (minimum) state of the total potential energy. The outer model performs global solution for cross-sections that are rigid in their own plane but includes the out-of-plane warping. The overall solution is capable of determining the influence of the in-plane warping on any existing approximate numerical scheme that do not include this deformation component. The results correlate well with known analytic solutions for isotropic tubes under pure bending. A parametric study of the relative importance of the in-plane warping as a function of the geometry and the loading parameters in rectangular thin-walled isotropic and composite beams is also presented along with some buckling considerations.     

Exploring the Effects of Glycosylation and Etherification of the Side Chains of the Anticancer Drug Mitoxantrone

Herein we report the synthesis and biological evaluation of symmetric and asymmetric analogues of the DNA intercalating drug mitoxantrone (MTX) in which the side chains of the parent drug were modified through glycosylation or methyl etherification. Several analogues with glycosylated side chains exhibited higher DNA affinity than the parent MTX. The most potent in vitro cytotoxicity was observed for MTX analogue 8 (1,4‐dimethoxy‐5,8‐bis[2‐(2‐methoxyethylamino)ethylamino]anthracene‐9,10‐dione) with methoxy ether containing side chains. Treatment of melanoma‐bearing mice with MTX or analogue 8 decreased the intraperitoneal tumor burden relative to untreated mice; the effect of 8 was less pronounced than that of MTX. In vitro metabolism assays of MTX with rabbit liver S9 fraction gave rise to several metabolites; almost no metabolites were detected for MTX analogue 8 . The results presented indicate that derivatization of the MTX side chain primary hydroxy groups may result in a significant improvement in DNA affinity and lower susceptibility to the formation of potentially toxic metabolites.     

The Herbivore-Induced Plant Volatile Methyl Salicylate Negatively Affects Attraction of the Parasitoid <Emphasis Type="Italic">Diadegma semiclausum</Emphasis>

The indirect defense mechanisms of plants comprise the production of herbivore-induced plant volatiles that can attract natural enemies of plant attackers. One of the often emitted compounds after herbivory is methyl salicylate (MeSA). Here, we studied the importance of this caterpillar-induced compound in the attraction of the parasitoid wasp Diadegma semiclausum by using a mutant Arabidopsis line. Pieris rapae infested AtBSMT1-KO mutant Arabidopsis plants, compromised in the biosynthesis of MeSA, were more attractive to parasitoids than infested wild-type plants. This suggests that the presence of MeSA has negative effects on parasitoid host-finding behavior when exposed to wild-type production of herbivore-induced Arabidopsis volatiles. Furthermore, in line with this, we recorded a positive correlation between MeSA dose and repellence of D. semiclausum when supplementing the headspace of caterpillar-infested AtBSMT1-KO plants with synthetic MeSA.     

DSP内核的演变

首先,为什么及什么时候必须使用DSP？我们可以先从应用的角度进行探讨。举个例说,手机通常需要至少2个DSP引擎,一个用于通信工作,另一个用于应用处理。在通信方面,通话一端的语音信号经数字化和压缩（DSP的一个典型功能）,被调制为一个无线信号（另一个DSP32作）,再通过无线基础设施发送到通话另一端,然后执行解调解压（也是DSP的功能）。