基于网格的科技信息服务平台的设计与实现

针对当前科技信息网普遍存在的资源问题,结合网格技术,提出一个能够有效屏蔽网格资源异构性和动态性的科技信息服务平台,并对该平台实现的各种关键技术进行了有效的分析和研究,研究结果对当前科技信息网的发展有较大的借鉴作用。     

某型特种车倒车影像控制器电磁兼容分析及优化措施

本文针对某特种车倒车影像控制器设备在CE102和RE102测试项中的测试结果超标问题,结合测试结果,分析了测试结果超标的原因以及设备电磁兼容设计的关键点;然后结合电磁兼容设计原则,改进了电磁干扰的抑制方法,对辐射源和抗干扰能力薄弱处加强了滤波和屏蔽,对壳体加强了接地处理;最后进行测试验证,结果表明,改进后的方法可有效解...     

Automatic selection of arterial input function on dynamic contrast-enhanced MR images

Dynamic susceptibility contrast-magnetic resonance imaging (DSC-MRI) data analysis requires the knowledge of the arterial input function (AIF) to quantify the cerebral blood flow (CBF), volume (CBV) and the mean transit time (MTT). AIF can be obtained either manually or using automatic algorithms. We present a method to derive the AIF on the middle cerebral artery (MCA). The algorithm draws a region of interest (ROI) where the MCA is located. Then, it uses a recursive cluster analysis on the ROI to select the arterial voxels. The algorithm had been compared on simulated data to literature state of art automatic algorithms and on clinical data to the manual procedure. On in silico data, our method allows to reconstruct the true AIF and it is less affected by partial volume effect bias than the other methods. In clinical data, automatic AIF provides CBF and MTT maps with a greater contrast level compared to manual AIF ones. Therefore, AIF obtained with the proposed method improves the estimate reliability and provides a quantitatively reliable physiological picture.     

Two-laser, large-field hyperspectral microarray scanner for the analysis of multicolor microarrays

We describe the development and operation of a two-laser, large-field hyperspectral scanner for analysis of multicolor genotyping microarrays. In contrast to confocal microarray scanners, in which wavelength selectivity is obtained by positioning band-pass filters in front of a photomultiplier detector, hyperspectral microarray scanners collect the complete visible emission spectrum from the labeled microarrays. Hyperspectral scanning permits discrimination of multiple spectrally overlapping fluorescent labels with minimal use of optical filters, thus offering important advantages over standard filter-based multicolor microarray scanners. The scanner uses two-sided oblique line illumination of microarrays. Two lasers are used for the excitation of dyes in the visible and near-infrared spectral regions. The hyperspectral scanner was evaluated with commercially available two-color calibration slides and with in-house-printed four-color microarrays containing dyes with spectral properties similar to their commercial genotyping array counterparts.     

渭河干流径流变化趋势及突变分析

流域水资源量的减少对区域水资源的利用、人类生存环境和经济社会发展等存在着重大影响,通过分析渭河干流径流量变化趋势和突变情况,为渭河流域水量调度和水资源管理提供科学支撑。采用Mann-Kendall非参数检验、累积距平、有序聚类、滑动t检验和R/S等方法分析渭河干流6个典型水文站1956—2015年径流量的历史演变规律、突变点和未来变化趋势。结果表明:渭河干流各站点的年和季节径流量均呈减少趋势。各站点的春、夏季节减少趋势的幅度大于秋、冬季节;从上游到下游,减少趋势的幅度越来越小。上游各站点呈现增加-平稳-减小的变化过程,且存在1970和1993年2个突变点,中游和下游各站点呈现增加-波动-平稳-减小的变化过程,且存在1968和1993年2个突变点。渭河干流各站点年和季节径流量Hurst指数均大于0.5,即未来变化趋势与历史演变规律呈正相关性,表明渭河干流各站点径流量具有持续下降的趋势,相应部门应高度重视这一现象,制定合理的流域水资源管理对策。     

无线传感器网络路由协议性能研究

无线传感器网络是目前网络研究的热点,其路由协议的设计是最具挑战性的问题之一,对目前典型的无线传感器网络的路由协议进行分类研究和性能分析,设计并实现了在NS2环境下典型协议的仿真场景和性能分析比较。对无线传感器网络路由协议的研究和组网具有参考指导意义。     

加热的GaAs中锰和铁的热再分布

应用光学、电学、质谱和谐振技术,发现非掺杂的体GaAs样品中锰和铁的本底浓度为(?)10~(15)cm~(-3),当加热时进行再分布,于近表面区形成一个浓度约为10~(17)cm~(-3)的薄(1～3μm)层,并指出锰的再分布能引起表面导电类型的改变。     

《电荷》教学设计比较研究

教学片段对比展示 片段一：多媒体环境 河北省武安市实验中学 孙建恩 1．视频导入,激疑引趣 师：首先,请大家观看视频。 教师播放视频——《有趣的电现象》（如图1）。     

Proteomic analysis in cerebrospinal fluid of patients with atypical nonketotic hyperglycinemia and pulmonary hypertension - A pilot study

A variant phenotype of nonketotic hyperglycinemia has been described by our group associated with pulmonary hypertension. The aim of this study is to investigate the cerebrospinal fluid proteomes to get an insight into this neurodegenerative process producing leukoencephalopathy with white matter spongiform degeneration. DIGE and MALDI-TOF-TOF analyses were performed to carry out the proteomic study of four patients against three normal controls and one additional control of a classical nonketotic hyperglycinemia. The differential proteomic analysis showed a displacement of some series of spots toward the acidic side. The shifted proteins showed a high degree of carbonylation and increased methionine sulfoxidation was found in cystatin C and in vitamin-D-binding protein. These findings in addition to the increase of serum malondialdehyde concentration provide evidence of an oxidative stress in the patients under study, which is probably systemic rather than mainly confined to the CNS. The similarities of our findings with those found in other neurodegenerative diseases suggest that oxidative damage is commonly involved in these pathologies. DIGE technology improves the 2-D PAGE differential analysis and it is suitable in proteomic studies with a small number of cases.