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The high affinity growth hormone-binding protein (GHBP) circulates in human blood and represents the extracellular domain of the growth hormone (GH) receptor. It is well known that repetitive bouts of endurance type exercise result in increased integrated GH secretion. As the effects of chronic exercise on plasma GHBP levels have never been studied systematically, we investigated the effect of 2 weeks of intense endurance training on plasma GHBP as well as on plasma insulin-like growth factor (IGF)-I levels in 10 healthy, young, non-obese men. IGF-I was measured as an indicator of the effects of GH release. We also studied 10 control subjects matched for sex, age and activity, who were instructed not to change their customary activities. GHBP was determined by FPLC size exclusion chromatography and subsequent Scatchard plot analysis of the binding data; IGF-I levels were measured by RIA. The results showed that plasma IGF-I and GHBP levels were increased in the subjects who followed the training program. IGF-I and GHBP changed from 252 +/- 56 ng/ml and 912 +/- 59 pmol/l before training, to 344 +/- 61 ng/ml (p < 0.01) and 1020 +/- 48 pmol/l (p < 0.01), respectively. Another effect of the training was that the aerobic capacity of these subjects was better utilized and endurance was improved. In contrast, plasma IGF-I, GHBP, utilization of aerobic capacity and endurance did not change significantly in the control subjects. We conclude that two weeks of strenuous endurance training lead to increased plasma IGF-I and high affinity GHBP levels. 相似文献
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65.
Yangyang Zhang Chunlin Ji Malik W. O'Brien D. Edwards D. 《Wireless Communications, IEEE Transactions on》2009,8(9):4393-4399
In this letter, we propose a novel receive antenna selection algorithm based on cross entropy optimization to maximize the capacity over spatially correlated channels in multiple-input multiple-output (MIMO) wireless systems. The performance of the proposed algorithm is investigated and compared with the existing schemes. Simulation results show that our low complexity algorithm can achieve near-optimal results that converge to within 99% of the optimal results obtained by exhaustive search. In addition, the proposed algorithm achieves near-optimal results irrespective of the mutual relationship between the number of transmit and receive antennas, the statistical properties of the channel and the operating signal-to-noise ratio. 相似文献
66.
This article describes the results of an investigation concerning with the failure of a pipe which was carrying oil from the
control oil unit to the steam turbine control valves servomotor. The failure was in the form of a crack, propagating horizontally
along the pipe. The crack initiated on the outside of the pipe. The cause of the failure was investigated by conducting visual
examination, detailed macro and microstructural examinations and determining the composition of material from the failed pipe.
The composition of the pipe material was analyzed by atomic absorption spectrometer. The failure of the oil pipe was attributed
to stress corrosion cracking. The pipe material is A312 TP 304L. Recommendation to minimize such failures includes coating
the pipe to prevent contact with chloride from the surrounding marine environment. 相似文献
67.
O.P. Malik G.S. Hope M.A.H. Sheirah 《International Journal of Electrical Power & Energy Systems》1983,5(3):159-165
The processing capability of computers makes it feasible to implement sophisticated techniques for process control. However, to minimize the software development costs, it is desirable to develop algorithms that can have a wider application. In keeping with this, an AVR and speed governor for a generating unit have been designed using the same algorithm, called the selftuning regulator. The selftuning AVR and speed governor have been implemented using a microprocessor and a minicomputer online. The feasibility of developing unified algorithms is demonstrated by means of realtime tests, in which the two controllers are used simultaneously for a generating unit physical model. 相似文献
68.
O.P. Malik G.S. Hope Ju M. Gorski V.A. Ushakov 《International Journal of Electrical Power & Energy Systems》1983,5(1):61-71
Results of experimental tests carried out with microprocessor-based voltage and speed regulators using a digital-analogue-physical model complex of a large power system at the Siberian Power Institute of the USSR Academy of Sciences are described. The physical test facility, and the test objectives and procedures are also outlined. Tests were carried out on a Soviet-built microprocessor AVR and a Canadian-built microprocessor AVR and speed governor. The work described shows that the development of speed and voltage regulators using microprocessors is a feasible and promising proposition. 相似文献
69.
GM Malik 《Canadian Metallurgical Quarterly》1998,59(3):397-398
In a retrospective case-control study of 58 cases of human brucellosis, adjusted mean serum calcium levels were found to be significantly higher in patients with brucellosis compared with controls: mean (95% confidence interval) = 2.39 (2.35-2.42) mmol/L versus 2.30 (2.26-2.34) mmol/L (P = 0.0012). The possible mechanisms underlying the cause of hypercalcemia in human brucellosis are discussed. 相似文献
70.