Elderly fall detection based on multi-stream deep convolutional networks

Multimedia Tools and Applications - Fall is the biggest threat to seniors, with significant emotional, physical and financial implications. It is the major cause of serious injuries, disabilities,...     

A novel architecture design for VLSI implementation of integer DCT in HEVC standard

This paper presents novel hardware of a unified architecture to compute the 4?×?4, 8?×?8, 16?×?16 and 32?×?32 efficient two dimensional (2-D) integer DCT using one block 1-D DCT for the HEVC standard with less complexity and material design. As HEVC large transforms suffer from the huge number of computations especially multiplications, this paper presents a proposition of a modified algorithm reducing the computational complexity. The goal is to ensure the maximum circuit reuse during the computation while keeping the same quality of encoded videos. The hardware architecture is described in VHDL language and synthesized on Altera FPGA. The hardware architecture throughput reaches a processing rate up to 52 million of pixels per second at 90 MHz frequency clock. An IP core is presented using the embedded video system on a programmable chip (SoPC) for implementation and validation of the proposed design. Finally, the proposed architecture has significant advantages in terms of hardware cost and improved performance compared to related work existing in the literature. This architecture can be used in ultra-high definition real-time TV coding (UHD) applications.

     

A GGP approach to solve non convex min-max predictive controller for a class of constrained MIMO systems described by state-space models

This paper proposes a new method to solve non convex min-max predictive controller for a class of constrained linear Multi Input Multi Output (MIMO) systems. A parametric uncertainty state space model is adopted to describe the dynamic behavior of the real process. Moreover, the output deviation method is used to design the j-step ahead output predictor. The control law is obtained by the resolution of a non convex min-max optimization problem under input constraints. The key idea is to transform the initial non convex optimization problem to a convex one by means of variable transformations. To this end, the Generalized Geometric Programming (GGP) which is a global deterministic optimization method is used. An efficient implementation of this approach will lead to an algorithm with a low computational burden. Simulation results performed on Multi Input Multi Output (MIMO) system show successful set point tracking, constraints satisfaction and good non-zero disturbance rejection.     

Fusion intermediates of HIV-1 gp41 as targets for antibody production: design, synthesis, and HR1-HR2 complex purification and characterization of generated antibodies

The objective of this project was to study the interaction between HR1 and HR2, the stability of the complex formed, and to characterize the antibodies produced against monomeric HR1 and HR2 peptides as well as the HR1-HR2 complex. In this work, HR1 was mimicked by peptide N36, and HR2 was mimicked by peptide C34L and its analogues C34M2, C34M3, and C34D. Whereas C34M2 and C34M3 are partially composed of D-amino acids, C34D has same sequence as C34L, but is assembled entirely of D-amino acids. Using CD analysis, SPR assays, and gel filtration chromatography, we demonstrate the physical interaction between N36 and C34L and its analogues C34M2 and C34M3, but not C34D. We show that the HR1-HR2 complex is formed rapidly (<1?min) and remains stable, as demonstrated by its inability, in contrast to each free peptide, to inhibit the formation of syncytia. To generate antibodies with predetermined specificity against the transiently exposed intermediate that corresponds to the six-helix bundle structure, purified preformed HR1-HR2 complex was used, in parallel with monomeric HR1 and HR2 peptides, as immunogens in mice. Although the produced antibodies recognize total HIV-1 envelope glycoproteins in ELISA, they are unable to neutralize HIV-1-mediated fusion at 37?°C. However, if the incubation with these antibodies is carried out at 27?°C, a temperature that allows stabilization of the transient intermediate complex, anti-peptide antibodies are able to bind their corresponding domains in HeLa cells expressing HIV-1 gp41 in co-culture with HeLa CD4-CCR5/CXCR4 during the dynamic mechanism of membrane fusion. In agreement with the latter results, these antibodies, if previously incubated for 2?h at 27?°C, are able to strongly neutralize HIV-1 entry by membrane fusion, as shown by their ability to block the formation of syncytia.