A statistical view of iterative methods for linear inverse problems

In this article, we study the problem of recovering the unknown solution of a linear ill-posed problem, via iterative regularization methods, from a statistical point of view. The basic purpose of the paper is to develop adaptive model selection techniques for determining the regularization parameters, i.e., the iteration index. We assume observations are taken over a fixed grid and we consider solutions over a sequence of finite-dimensional subspaces. Based on concentration inequalities techniques, we derive non-asymptotic optimal upper bounds for the mean square error of the proposed estimator.     

Open air calibration with temperature compensation of a luminescence quenching-based oxygen sensor for portable instrumentation

This report addresses the task of calibrating an optical sensor for oxygen determination. Detailed analyses of the functional dependences from our measurement system results have been carried out with the additional aim of temperature compensation. As a result, an empirical calibration function has been successfully derived for the luminescent quenching-based oxygen sensor included in a self-designed portable instrument. This function also compensates for the temperature influence on the quenching luminescence process in the range from 0 to 45 degrees C. Moreover, the calibration procedure is extremely simple because only a single standard is needed. In fact, the oxygen measurement system can be calibrated with exposure to an open air atmosphere, and therefore, neither laboratory standards nor trained personnel are required. The method has been applied to a set of 11 units of the mentioned sensor (up to 24% oxygen concentration) giving an overall deviation between our calibrated system results and the laboratory standards of 0.3% oxygen concentration (calculated with 95% confidence level). The proposed calibration function has shown itself to be applicable for different sensing film thicknesses and luminophore concentrations using the same fittings parameter. Additionally, this function has been successfully applied to other oxygen dyes. Good agreement has also been found when the performance of the instrument was compared to a commercially available portable instrument based on an electrochemical sensor. We believe that this work could be an interesting finding for spreading the use of optical sensors for atmospheric oxygen determination in commercial measurement equipment for different purposes in confined working atmospheres, such as mines, undergrounds, warehouses, vehicles, and ships.     

Phenotypic study on total and partial lifetime traits for dairy ewes

A data file on 36,396 lactations was used to determine the strength of the phenotypic relationship between productive, reproductive and lifespan traits for 7935 Spanish Churra ewes. These ewes first lambed between 1989 and 1997 and belonged to 23 flocks. The study took into account four lifespan traits (lifetime, productive life, useful life and lifetime score), three productive traits (total milk yield produced during lifetime, lambs weaned during ewe lifetime and total revenues from sold milk and weaned lambs during lifetime) and two reproductive traits (age at first lambing and mean interval between successive lambings). Moreover, milk yield and revenues from sold milk and weaned lambs were calculated per day of lifetime, productive life and useful life. Partial lifespan traits were considered for the first three parities. The model included flock, birth year within flock and season of birth of the ewe as fixed effects. The first two effects contributed significantly to variation in all traits, while season significantly affected lifespan traits, productive traits and age at first lambing. Milk production level was added to the model for lifespan traits only. It significantly contributed to explaining the variation in all lifespan traits with high percentage of variance explained averaging 14.91%. Lifetime averaged 2324 d. Productive life accounted for 57% of lifetime while useful life represented 50% of productive life. Age at first lambing averaged 622 d and average days dry during lifetime was 560. During lifetime, ewes gave an average of 4.6 parities, 6.5 weaned lambs and 636 l of milk. Average revenue from milk and lambs during lifetime was 673 euros. Milk/day of lifetime, productive life and useful life averaged 0.26, 0.51 and 0.93 l, respectively. The corresponding per-day revenues from sold milk and weaned lambs were, 0.27 euros, 0.55 euros and 1.01 euros, respectively. Lifespan and productive traits had strong relationships (rp among these traits ranged between 0.75 and 0.95). Two-parity and three-parity per-day milk yield had moderately high correlation (0.70-0.83) with total lifetime per-day milk yield traits. Therefore, good use of these traits would be helpful in determining best individuals early in life.     

Protein Experiment: Scientific Data Processing Platform for On-Flight Experiment Tuning

In 2009, the PROTEIN experiment was run on board of the Columbus module of the International Space Station to investigate the crystallization of proteins in microgravity using the Protein Crystallization Diagnostics Facility. This instrument was designed to allow almost real time modification of remote-operated space experiments on request by the Science Team. The complexity of the experiments and the expected high volume of raw scientific data required the development of ad-hoc analysis tools in order to provide scientist with a quick and in-depth picture of experiment progress. The integrated data analysis platform presented in this paper allowed early inspection of running experiment results and provided information for impromptu, fine-tuning experimental conditions. The feedback loop starting with remote data acquisition, followed by on ground analysis performed by the platform and finishing with experiment redesign and update, is described through several examples.     

Production scheduling in a market-driven foundry: a mathematical programming approach versus a project scheduling metaheuristic algorithm

This paper describes a real problem in a market-driven medium sized foundry delivering a wide range of castings to different markets. The problem consists of finding an efficient production plan to schedule the different processes (moulding, furnacing, cutting, tooling, etc.) needed to the manufacture of the pieces. Different objectives and resources and technical constraints must be taken into account. To solve this problem we have first developed a more classical integer linear programming approach based on a rolling horizon strategy. The most innovative contribution of the paper is that it models the problem as a project scheduling problem. Based on this model we present a metaheuristic algorithm that adapts techniques from the area. Computational experiments comparing both approaches are provided on instances created by a generator simulating real instances.     

Current asthma and respiratory symptoms among pupils in Shanghai, China: influence of building ventilation, nitrogen dioxide, ozone, and formaldehyde in classrooms

We investigated 10 naturally ventilated schools in Shanghai, in winter. Pupils (13-14 years) in 30 classes received a questionnaire, 1414 participated (99%). Classroom temperatures were 13-21 degrees C (mean 17 degrees C), relative air humidity was 36-82% (mean 56%). The air exchange rate was 2.9-29.4 ac/h (mean 9.1), because of window opening. Mean CO2 exceeded 1000 ppm in 45% of the classrooms. NO2 levels were 33-85 microg/m3 indoors, and 45-80 microg/m3 outdoors. Ozone were 1-9 microg/m3 indoors and 17-28 microg/m3 outdoors. In total, 8.9% had doctors' diagnosed asthma, 3.1% wheeze, 23.0% daytime breathlessness, 2.4% current asthma, and 2.3% asthma medication. Multiple logistic regression was applied. Observed indoor molds was associated with asthma attacks [odds ratio (OR) = 2.40: P < 0.05]. Indoor temperature was associated with daytime breathlessness (OR = 1.26 for 1 C; P < 0.001), and indoor CO2 with current asthma (OR = 1.18 for 100 ppm; P < 0.01) and asthma medication (OR = 1.15 for 100 ppm; P < 0.05). Indoor NO2 was associated with current asthma (OR = 1.51 for 10 microg/m3; P < 0.01) and asthma medication (OR = 1.45 for 10 microg/m3; P < 0.01). Outdoor NO2 was associated with current asthma (OR = 1.44 for 10 microg/m3; P < 0.05). Indoor and outdoor ozone was negatively associated with daytime breathlessness. In conclusion, asthma symptoms among pupils in Shanghai can be influenced by lack of ventilation and outdoor air pollution from traffic. Practical Implications Most urban schools in Asia are naturally ventilated buildings, often situated in areas with heavy ambient air pollution from industry or traffic. The classes are large, and window opening is the only way to remove indoor pollutants, but this results in increased exposure to outdoor air pollution. There is a clear need to improve the indoor environment in these schools. Building dampness and indoor mold growth should be avoided, and the concept of mechanical ventilation should be introduced. City planning aiming to situate new schools away from roads with heavy traffic should be considered.     

Results of three courses of adriamycin, bleomycin, vindesine, and dacarbazine with subtotal nodal irradiation in 189 patients with nodal Hodgkin''s disease (stage I, II and IIIA)

This paper will explore the delivery of mental health nursing care within a neo-liberal model of mental health care delivery in New Zealand. Mental health nursing as a socially constructed activity occurs within a particular political context, which determines its role and function. This environment determines the nature of the nurse-patient relationship which is integral to the role of mental health nurses. Critical analysis of the New Zealand Government's neo-liberal health policies will be conducted to explore their effect on mental health care delivery and the nurse-patient relationship. Some of the ideologies and values maintained by current dominant discourses within nursing and the State are discussed. To establish therapeutic partnerships with service-users, mental health nurses are urged to critically analyse their practice and the context in which it occurs.