Transdermal Iontophoretic Delivery of Thyrotropin-Releasing Hormone Across Excised Rabbit Pinna Skin

Enhanced transport of a model peptide drug thyrotropin-releasing hormone (TRH), a tripeptide of molar mass 362 g and a pK_a 6.2, through excised rabbit pinna skin was achieved by means of iontophoresis with continuous current or monophase periodically pulsed current. The resulting flux in the steady state was proportional to the applied current density. In the transdermal iontophoretic delivery of TRH, the pulsed iontophoretic flux exceeded that obtained with a continuous current. At a low ionic strength, an increased degree of protonation in TRH increased the rate of permeation. The flux of TRH in a buffer at pH 4 is greater than that at pH 8 when the ionic strength is 0.1 M. At a greater ionic strength, the trend is reversed. The enhanced flux of unprotonated TRH during transdermal iontophoresis is attributed largely to electro-osmotic volume flow. An increased rate of permeation of TRH crossing the skin is achieved at low ionic strength, moderate pH, and a large duly cycle of current; the frequency of pulsed current had no significant influence on the rate of transdermal iontophoretic delivery of TRH.     

Analysis of dispersion characteristics for a circular dielectric waveguide with periodic metallic strips by using the method of lines

The dispersion characteristics of circular dielectric waveguide with periodic metallic strips are analyzed by the method of lines. The filter property of the metallic strip loaded structure is carefully investigated for both TE and TM modes. The brillioum diagrams for both TE₀₁ and TM₀₁ modes are given. A comparison is made between the results obtained by Galerkin's method and those calculated with the method of lines, and very good agreement has been found; the accuracy of the present method is thus justified. On the basis of the analysis, some useful guidelines for the design of the bandreject filters are suggested.     

混凝土受拉断裂的破坏机理

本文从试验现象出发,建立了以数理统计为基础的混凝土受拉全过程曲线方程。研究表明,混凝土受拉应力应变全曲线是混凝土试件内部的粘结界面与水泥胶合物在外拉力作用下逐步断裂造成的。文章所建立的方法不仅可以解释许多试验现象,模拟混凝土受拉全曲线,而且还可以得出试验中难以测出的结果。     

PAA-PSF交联复合膜的制备及对低浓度有机醇水溶液反渗透分离性能研究

进行了ＰＡＡ（ＰｏｌｙａｃｒｙｌｉｃＡｃｉｄ）－ＰＳＦ（Ｐｏｌｙｓｕｌｆｏｎｅ）交联复合膜的制备，研究了交联剂、添加剂对膜性能的影响，并通过扫描电镜观察了膜的断面结构．研究了ＰＡＡ－ＰＳＦ交联复合膜对低浓度有机醇类水溶液反渗透分离性能．发现对于１０００×１０－６乙醇水溶液截留率达到６６．２％，透过流束可达０．９×１０－６（ｍ３·ｍ－２·ｓ－１）．随醇的分子量的增加，截留率不断上升，对戊醇的截留率达９４．３％，而透过流束则保持相对稳定．对不同结构醇类的分离性能研究表明，截留率存在有：ｔｅｒｔ－＞ｓｅｃ－＞ｉｓｏ－＞ｎ－的规律．     

使用光纤放大器的频分复用光纤传输系统

报道了一个使用光纤放大器的两路非相干频分复用光纤传输实验系统。系统采用国产ＤＦＢ激光器作光源，用意大利生产的光纤放大器作在线放大器，用自制的光学谐振腔作光学滤波器和解复用器，采用ＦＳＫ调制制式，将１４０Ｍｂ／ｓ非归零伪随机码传输了５０公里，得到了很好的眼图。在频道间距为１０ＧＨｚ情况下，未观测到邻道干扰和光纤放大器的非线性现象。     

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本文介绍了采用复合吸收剂净化天然气的试验结果,在现有三甘醇等脱水剂中添加单乙醇胺,在脱水的同时脱除H_2S,在保证净化气露点低于-21℃的条件下,使净化气中H_2S含量亦低于5mg/m～3。     

Pi-coefficient analysis of update algorithms for adaptive systems

This paper finds the appropriate pi-coefficients for a parameter estimation adaptive system and uses them to analyze the stability of two estimation algorithms. The estimation error dynamics of the system are modeled by a linear time-invariant subsystem and a nonlinear time-varying update law in a feedback loop. Then the so-called max-p problems are formulated and solved to obtain the pi-coefficients for the linear subsystem and nonlinear update low. For the investigated system, the quantitative results show that the least-squares update algorithm has larger stability range than that of the gradient algorithm, and the σ-modification scheme gives larger stability ranges for both algorithms.     

Formation Mechanism of MoO3-Doped YSr2Cu3Oy Using the Citrate Process

The formation mechanism of the synthesis of MoO₃-doped YSr₂Cu₃O _y powders using the citrate process was investigated. It was shown that the precursor phase (Sr_{1- x} Y _x )₁₄Cu₂₄O₄₁ played a crucial role in forming the superconducting phase. It was found that the precursor phase (Sr_{1- x} Y _x )₁₄Cu₂₄O₄₁ interacted with water and decomposed when it was heavily milled and heated.     

水泥膨胀珍珠岩砂浆的保温试验研究与应用

荆江分洪北闸加固工程２号护坦（斜面）混凝土的保温层采用了水泥膨胀珍珠岩砂浆，并对这种材料的保温效果进行了试验研究。试验表明：水泥膨胀珍珠岩砂浆降低最高温差，减小内表温差，缩小表温变幅和防止混凝土表面裂缝效果显著。在北闸２号护坦混凝土表面铺设１万平方米保温层，获得良好效果。