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991.
992.
Lu Jin Yang Yao Sun Jingyuan Huang Zhengliang Yang Yongrong Wang Jingdai 《中国炼油与石油化工》2022,(1):135-148
The hydrodynamic instability of the axial flow pump in a loop reactor has long been a troubling issue to be solved in the polyethylene industry due to the lack of a better mechanismic understanding.Generally,the instability of an axial flow pump can be reflected by the fluctuation of the pump head.In this study,the transient computational fluid dynamics(CFD)simulation is adopted to study the hydrodynamic instability of the axial flow pump used in an ethylene polymerization loop reactor.The resul... 相似文献
993.
Yanhe Li Xiaoming Li Xin Li Suiqun Yang Bingui Wang Honglei Li 《International journal of molecular sciences》2022,23(10)
Six novel verrucosidin derivatives, namely, poloncosidins A–F (1–6), together with one known analogue (7), were isolated and identified from the deep-sea-derived fungus Penicillium polonicum CS-252, which was obtained from cold-seep sediments collected in the South China Sea at a depth of 1183 m. Their structures were mainly established on the basis of a detailed interpretation of NMR spectroscopic and mass spectrometric data. The relative and absolute configurations of compounds 1–6 were determined by ECD calculations and a DP4+ probability analysis. Compounds 1–5 represent the first examples of verrucosidins with a 2,5-dihydrofuran ring which is uncommon among the known analogues. These compounds exhibited inhibitory activities against several human and aquatic pathogens with MIC values ranging from 4 to 32 μg/mL. 相似文献
994.
995.
Jinfu Lou Fuqiang Gao Jinghe Yang Yanfang Ren Jianzhong Li Xiaoqing Wang Lei Yang 《国际煤炭科学技术学报(英文)》2021,(5):938-955
The evolution of mining-induced stress field in longwall panel is closely related to the fracture field and the breaking characteristics of strata.Few laborator... 相似文献
996.
Shi Shun Wang JiaYu Wang TianRan Ren Hui Zhou YuHao Li Gao He ChaoLiang Chen XueSi 《中国科学:技术科学(英文版)》2021,64(3):641-650
Science China Technological Sciences - Glycopolypeptides as analogs of glycoproteins or glycosaminoglycans represent attractive building blocks for the construction of biomimetic biomaterials.... 相似文献
997.
Ying Yang Hui-Yun Chen Hua Hao Ke-Jian Wang 《International journal of molecular sciences》2022,23(10)
Scyreprocin is an antimicrobial peptide first identified in the mud crab Scylla paramamosain. Herein, we showed that its recombinant product (rScyreprocin) could significantly inhibit the growth of human lung cancer NCI-H460 cells (H460), but showed no cytotoxicity to human lung fibroblasts (HFL1). rScyreprocin was a membrane-active peptide that firstly induced the generation of reactive oxygen species (ROS) in H460, and led to endoplasmic reticulum stress and Ca2+ release, which resulted in mitochondrial dysfunction and subsequently activation of caspase-3 cascades, and ultimately led to apoptosis. The comprehensive results indicated that rScyreprocin exerted anticancer activity by disrupting cell membrane and inducing apoptosis. The in vivo efficacy test demonstrated that intratumoral injection of rScyreprocin significantly inhibited the growth of H460 xenografts, which was close to that of the cisplatin (inhibition rate: 69.94% vs. 80.76%). Therefore, rScyreprocin is expected to become a promising candidate for the treatment of lung cancer. 相似文献
998.
Yao Yu Lu Ma Xinying Wang Zhi Zhao Wei Wang Yunxin Fan Kunquan Liu Tingting Jiang Ziwei Xiong Qisheng Song Changqing Li Panting Wang Wenjing Ma Huanan Xu Xinyu Wang Zijing Zhao Jianfei Wang Hongsheng Zhang Yongmei Bao 《International journal of molecular sciences》2022,23(10)
Rice blast is one of the main diseases in rice and can occur in different rice growth stages. Due to the complicated procedure of panicle blast identification and instability of panicle blast infection influenced by the environment, most cloned rice resistance genes are associated with leaf blast. In this study, a rice panicle blast resistance gene, Pb2, was identified by genome-wide association mapping based on the panicle blast resistance phenotypes of 230 Rice Diversity Panel 1 (RDP1) accessions with 700,000 single-nucleotide polymorphism (SNP) markers. A genome-wide association study identified 18 panicle blast resistance loci (PBRL) within two years, including 9 reported loci and 2 repeated loci (PBRL2 and PBRL13, PBRL10 and PBRL18). Among them, the repeated locus (PBRL10 and PBRL18) was located in chromosome 11. By haplotype and expression analysis, one of the Nucleotide-binding domain and Leucine-rich Repeat (NLR) Pb2 genes was highly conserved in multiple resistant rice cultivars, and its expression was significantly upregulated after rice blast infection. Pb2 encodes a typical NBS-LRR protein with NB-ARC domain and LRR domain. Compared with wild type plants, the transgenic rice of Pb2 showed enhanced resistance to panicle and leaf blast with reduced lesion number. Subcellular localization of Pb2 showed that it is located on plasma membrane, and GUS tissue-staining observation found that Pb2 is highly expressed in grains, leaf tips and stem nodes. The Pb2 transgenic plants showed no difference in agronomic traits with wild type plants. It indicated that Pb2 could be useful for breeding of rice blast resistance. 相似文献
999.
1000.
Yuyang Wang Hui Nie Jinsong Han Yaxun An Yu-Mo Zhang Sean Xiao-An Zhang 《光:科学与应用(英文版)》2021,10(3):327-340
The technological revolution of long-awaited energy-saving and vision-friendly displays represented by bistable display technology is conning.Here we discuss methods,challenges,and opportunities for implementing bistable displays in terms of molecular design,device structure,further expansion,and required criteria,hopefully benefiting the light-related community. 相似文献