霍尔传感器状态监测电路的设计及其应用

针对一般电流、电压互感器存在体积大、精度不高、使用不便的缺点,而霍尔传感器具有精度高、线性好、频带宽、响应快等优点的情况,以霍尔效应原理为基础,霍尔传感器为对象,设计了霍尔传感器状态监测电路并制作了相应的电路板.该电路板能同时分别监测三路电流和电压量,且测量电阻可根据实际工况随时更换,具有体积小(13×10cm)、方便、快捷的特点.最后用其进行了液压动力系统状态监测实验,并与一般电流互感器的测量结果作了对比分析.结果表明,设计的电路合理,制作的电路板工程实用价值较好.     

超大尺寸干气密封在冶金行业原料气压缩机上的应用

介绍了超大尺寸干气密封在冶金行业原料气压缩机上的应用,包括密封与控制系统设计方案以及现场安装调试情况.提出了超大尺寸干气密封设计、制造、检验和试验,以及现场安装、拆卸的技术难点,并指出了使用中应注意的问题.     

围挡式洁净区的单向流特性研究

通过实验分析围挡式洁净区的3个特性指标，即：流线平行度、乱流度和下限风速，并指出其应用价值和市场前景。     

计量型原子力显微镜

本文报导国际上研制的第一台在纳米测量中，在中等测量范围内，具有微型光纤传导激光干涉三维测量系统、可自校准和进行绝对测量的计量型原子力显微镜。它的诞生，可使目前用于纳米技术研究的扫描隧道显微镜定量化，并将其所测量的纳米量值直接与米定义相衔接。使人们更加准确地了解纳米范围内的各种物理现象，并对它们进行更精确的分析。文章对计量型原子力显微镜进行了理论分析，提出了对各种测量误差的抑制及其补偿方法，并进行了大量的实验，得到良好的结果。目前，该计量型原子力显微镜在其测量范围内，任意两点间距离的测量不确定度为Ｕ９５＝５ｎｍ＋２×１０－４ｌ；在ｚ－轴上的测量不确定度为Ｕ９５＝（１．１～１．２ｎｍ）＋２×１０－４ｈ。     

Integrated microfluidic system enabling protein digestion, peptide separation, and protein identification

An integrated platform is presented for rapid and sensitive protein identification by on-line protein digestion and analysis of digested proteins using electrospray ionization mass spectrometry or transient capillary isotachophoresis/capillary zone electrophoresis with mass spectrometry detection. A miniaturized membrane reactor is constructed by fabricating the microfluidic channels on a poly(dimethylsiloxane) substrate and coupling the microfluidics to a poly(vinylidene fluoride) porous membrane with the adsorbed trypsin. On the basis of he large surface area-to-volume ratio of porous membrane media, adsorbed trypsin onto the poly(vinylidene fluoride) membrane is employed for achieving ultrahigh catalytic turnover. The extent of protein digestion in a miniaturized membrane reactor can be directly controlled by the residence time of protein analytes inside the trypsin-adsorbed membrane, the reaction temperature, and the protein concentration. The resulting peptide mixtures can either be directly analyzed using electrospray ionization mass spectrometry or further concentrated and resolved by electrophoretic separations prior to the mass spectrometric analysis. This microfluidic system enables rapid identification of proteins in minutes instead of hours, consumes very little sample (nanogram or less), and provides on-line interface with upstream protein separation schemes for the analysis of complex protein mixtures such as cell lysates.     

Enhanced and Differential Capture of Circulating Tumor Cells from Lung Cancer Patients by Microfluidic Assays Using Aptamer Cocktail

Collecting circulating tumor cells (CTCs) shed from solid tumor through a minimally invasive approach provides an opportunity to solve a long‐standing oncology problem, the real‐time monitoring of tumor state and analysis of tumor heterogeneity. However, efficient capture and detection of CTCs with diverse phenotypes is still challenging. In this work, a microfluidic assay is developed using the rationally‐designed aptamer cocktails with synergistic effect. Enhanced and differential capture of CTCs for nonsmall cell lung cancer (NSCLC) patients is achieved. It is also demonstrated that the overall consideration of CTC counts obtained by multiple aptamer combinations can provide more comprehensive information in treatment monitoring.     

现代网络技术对计量业务管理工作的促进

本文主要介绍在计量业务管理过程中如何利用网络信息技术来促进计量业务管理模式的创新,进而提高业务管理的工作效率。     

PU／P（MA—DMA）／EP三组分IPN力学性能的研究

用同步法合成聚氨酯/聚(丙烯酸甲酯-甲基丙烯酸β-N,N′-2-甲基乙酯)/环氧树脂三组分互穿聚合物网络,对IPN组成、结构与性能的关系进行了讨论。结果表明,改变组成比可以得到相容性不同的IPN。本文认为组成比对IPN性能的影响较连续相为大,加入接枝剂可以有效地改变IPN的相容性。力学性能与组成网络的结构及缠结方式有关,组成比相同时,全IPN具有较大的应力值。加入填料,体系中发生“准交联”作用,使阻尼值增高,转变温度区域加宽。     

低重心大支承面浆砌片石构筑物拆除爆破技术

在城市拆除爆破中，用小孔爆破法拆除重心很低、支承面大的浆砌片石构筑物难度很大。本文通过用“集团装药”法拆除此类构筑物的工程实例，介绍这种方法的布药方式、药量计算及其适用条件。     

Creation of Nonspherical Microparticles through Osmosis‐Driven Arrested Coalescence of Microfluidic Emulsions

Droplet‐based microfluidics enable the production of emulsions and microparticles with spherical shapes, but the high‐throughput fabrication of nonspherical emulsions and microparticles still remains challenging because interfacial tension plays a dominant role during preparation. Herein, ionic liquids (ILs) containing salts, which possess sufficient osmotic pressure to realize water transport and phase separation, are introduced as inner cores of oil‐in‐oil‐in‐water double emulsions and it is shown that nonspherical emulsions can be constructed by osmosis‐driven arrested coalescence of inner cores. Subsequently, ultraviolet polymerization of the nonspherical emulsions leads to nonspherical microparticles. By tailoring the number, composition, and size of inner cores as well as coalescence time, a variety of nonspherical shapes such as dumbbell, rod, spindle, snowman, tumbler, three‐pointed star, triangle, and scalene triangle are created. Importantly, benefitting from excellent solvency of ILs, this system can serve as a general platform to produce nonspherical microparticles made from different materials. Moreover, by controlling the osmotic pressure, programmed coalescence of inner cores in double emulsions is realizable, which indicates the potential to build microreactors. Thus, a simple and high‐throughput strategy to create nonspherical microparticles with arrested coalescence shapes is developed for the first time and can be further used to construct novel materials and microreactors.