Applications of psychology to television programming: Formulation of program objectives.

Asserts that in preparing objectives of television programming for children the instructor must (a) recognize the needs and interests of his/her audience and (b) match them to his/her educational purposes. The techniques used to identify and implement methods of attaining the goals of the television programs "Sesame Street" and "The Electric Company" are discussed. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

BCI Meeting 2005--workshop on signals and recording methods.

This paper describes the highlights of presentations and discussions during the Third International BCI Meeting in a workshop that evaluated potential brain-computer interface (BCI) signals and currently available recording methods. It defined the main potential user populations and their needs, addressed the relative advantages and disadvantages of noninvasive and implanted (i.e., invasive) methodologies, considered ethical issues, and focused on the challenges involved in translating BCI systems from the laboratory to widespread clinical use. The workshop stressed the critical importance of developing useful applications that establish the practical value of BCI technology.     

Description of Structural Damage Caused by the Terrorist Attack on the Pentagon

On September 11, 2001, an airliner was intentionally crashed into the Pentagon. It struck at the first elevated slab on the west wall, and slid approximately 310?ft (94.5?m) diagonally into the building. The force of the collision demolished numerous columns and the fa?ade of the exterior wall, and induced damage to first-floor columns and the first elevated slab over an area approximately 90?ft (27.4?m) wide and 310?ft (94.5?m) long. None of the building collapsed immediately. The portion that remained standing, even after an intense fire, sustained substantial damage at the first-floor level.     

Toughness of the Pentagon Structure

On September 11, 2001, the reinforced concrete structure of the Pentagon Building was able to resist, without collapse, the impact of a large commercial airliner despite the total loss of 26 columns and severe damage to 15 columns at the ground level. The ensuing fire and related fire-fighting activities led to the collapse of a portion of the building approximately one-half hour after the impact. In this paper, the reasons for the demonstrated toughness of the reinforced concrete structure are examined and attributed to use of spiral columns, effective splicing of reinforcing bars, strong girders, and short span lengths.     

The Mediating Role of Self-Efficacy in the Development of Entrepreneurial Intentions.

The purpose of this study was to investigate the mediating role of self-efficacy in the development of students' intentions to become entrepreneurs. The authors used structural equation modeling with a sample of 265 master of business administration students across 5 universities to test their hypotheses. The results showed that the effects of perceived learning from entrepreneurship-related courses, previous entrepreneurial experience, and risk propensity on entrepreneurial intentions were fully mediated by entrepreneurial self-efficacy. Contrary to expectations, gender was not mediated by self-efficacy but had a direct effect such that women reported lower entrepreneurial career intentions. The authors discuss practical implications and directions for future research. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

The First Report on Scheme Revisited

Higher-Order and Symbolic Computation -     

Variable Expression of GABAA Receptor Subunit Gamma 2 Mutation in a Nuclear Family Displaying Developmental and Encephalopathic Phenotype

Mutations in GABA_A receptor subunit genes (GABRs) are a major etiology for developmental and epileptic encephalopathies (DEEs). This article reports a case of a genetic abnormality in GABRG2 and updates the pathophysiology and treatment development for mutations in DEEs based on recent advances. Mutations in GABRs, especially in GABRA1, GABRB2, GABRB3, and GABRG2, impair GABAergic signaling and are frequently associated with DEEs such as Dravet syndrome and Lennox–Gastaut syndrome, as GABAergic signaling is critical for early brain development. We here present a novel association of a microdeletion of GABRG2 with a diagnosed DEE phenotype. We characterized the clinical phenotype and underlying mechanisms, including molecular genetics, EEGs, and MRI. We then compiled an update of molecular mechanisms of GABR mutations, especially the mutations in GABRB3 and GABRG2 attributed to DEEs. Genetic therapy is also discussed as a new avenue for treatment of DEEs through employing antisense oligonucleotide techniques. There is an urgent need to define treatment targets and explore new treatment paradigms for the DEEs, as early deployment could alleviate long-term disabilities and improve quality of life for patients. This study highlights biomolecular targets for future therapeutic interventions, including via both pharmacological and genetic approaches.     

A Quantitative Genetic Study of Sclerotinia Head Rot Resistance Introgressed from the Wild Perennial Helianthus maximiliani into Cultivated Sunflower (Helianthus annuus L.)

Sclerotinia head rot (HR), caused by Sclerotinia sclerotiorum, is an economically important disease of sunflower with known detrimental effects on yield and quality in humid climates worldwide. The objective of this study was to gain insight into the genetic architecture of HR resistance from a sunflower line HR21 harboring HR resistance introgressed from the wild perennial Helianthus maximiliani. An F₂ population derived from the cross of HA 234 (susceptible-line)/HR21 (resistant-line) was evaluated for HR resistance at two locations during 2019–2020. Highly significant genetic variations (p < 0.001) were observed for HR disease incidence (DI) and disease severity (DS) in both individual and combined analyses. Broad sense heritability (H²) estimates across environments for DI and DS were 0.51 and 0.62, respectively. A high-density genetic map of 1420.287 cM was constructed with 6315 SNP/InDel markers developed using genotype-by-sequencing technology. A total of 16 genomic regions on eight sunflower chromosomes, 1, 2, 10, 12, 13, 14, 16 and 17 were associated with HR resistance, each explaining between 3.97 to 16.67% of the phenotypic variance for HR resistance. Eleven of these QTL had resistance alleles from the HR21 parent. Molecular markers flanking the QTL will facilitate marker-assisted selection breeding for HR resistance in sunflower.     

Transport network design of integrated networks with real-time dynamic routing

Integrated real-time dynamic routing (IRR) networks provide dynamic routing features for multiple classes-of-service on an integrated transport network. In a previous Journal paper it is shown that IRR networks allow reduced network management costs since with real-time dynamic routing a number of network operations are simplified or eliminated, leading to savings in operations costs and expenses. In this paper a new algorithm is described for the transport design of IRR networks which achieves near-optimal capacity engineering. In particular, a Karmarkar Algorithm optimal solution to the linear programming flow model achieves approximately a 5 to 8 percentage point reduction in network design cost in comparison to the designs of pre-planned dynamic networks solved with heuristic design techniques. The optimization techniques described in this and the previous Journal paper attain significant capital cost reductions and network performance improvements by properly modeling the more efficient operation of IRR networks.