Confirmatory Factor Analysis of the Psychopathy Checklist: Screening Version in Offenders With Axis I Disorders.

One hundred forty-nine inpatients within a maximum security psychiatric facility were assessed with the Psychopathy Checklist: Screening Version (PCL:SV; S. D. Hart, D. N. Cox, & R. D. Hare, 1995). Within the total sample, 68% had a psychotic disorder and 30% met criteria for psychopathy. Using confirmatory factor analysis, the authors tested the 2-factor PCL:SV model of psychopathy and recent 3- and 4-factor models. Results indicated good fit for each model, with the 4-factor model showing best overall fit. Structural equation modeling was used to determine which psychopathy factors predicted 6-month follow-up of inpatient aggression. The 2-, 3-, and 4-factor models, respectively, accounted for 16%.27%. and 3l% of the variance in aggression. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

On Logical Foundations of Multilevel Secure Databases

It is envisaged that the application of the multilevel security (MLS) scheme will enhance flexibility and effectiveness of authorization policies in shared enterprise databases and will replace cumbersome authorization enforcement practices through complicated view definitions on a per user basis. However, the critical problem with the current model is that the belief at a higher security level is cluttered with irrelevant or inconsistent data as no mechanism for attenuation is supported. Critics also argue that it is imperative for MLS database users to theorize about the belief of others, perhaps at different security levels, an apparatus that is currently missing and the absence of which is seriously felt.The impetus for our current research is the need to provide an adequate framework for belief reasoning in MLS databases. In this paper, we show that these concepts can be captured in a F-logic style declarative query language, called MultiLog, for MLS deductive databases for which a proof theoretic, model theoretic and fixpoint semantics exist. This development is significant from a database perspective as it now enables us to compute the semantics of MultiLog databases in a bottom-up fashion. We also define a bottom-up procedure to compute unique models of stratified MultiLog databases. Finally, we establish the equivalence of MultiLog's three logical characterizations—model theory, fixpoint theory and proof theory.     

Layout and results from the initial operation of the high-resolution x-ray imaging crystal spectrometer on the Large Helical Device

First results of ion and electron temperature profile measurements from the x-ray imaging crystal spectrometer (XICS) diagnostic on the Large Helical Device (LHD) are presented. This diagnostic system has been operational since the beginning of the 2011 LHD experimental campaign and is the first application of the XICS diagnostic technique to helical plasma geometry. The XICS diagnostic provides measurements of ion and electron temperature profiles in LHD with a spatial resolution of 2 cm and a maximum time resolution of 5 ms (typically 20 ms). Ion temperature profiles from the XICS diagnostic are possible under conditions where charge exchange recombination spectroscopy (CXRS) is not possible (high density) or is perturbative to the plasma (low density or radio frequency heated plasmas). Measurements are made by using a spherically bent crystal to provide a spectrally resolved 1D image of the plasma from line integrated emission of helium-like Ar(16 +). The final hardware design and configuration are detailed along with the calibration procedures. Line-integrated ion and electron temperature measurements are presented, and the measurement accuracy is discussed. Finally central temperature measurements from the XICS system are compared to measurements from the Thomson scattering and CXRS systems, showing excellent agreement.     

Synthetic Modular Antibody Construction by Using the SpyTag/SpyCatcher Protein-Ligase System

Efforts to engineer recombinant antibodies for specific diagnostic and therapy applications are time consuming and expensive, as each new recombinant antibody needs to be optimized for expression, stability, bio-distribution, and pharmacokinetics. We have developed a new way to construct recombinant antibody-like “devices” by using a bottom-up approach to build them from well-behaved discrete recombinant antibody domains or “parts”. Studies on antibody structure and function have identified antibody constant and variable domains with specific functions that can be expressed in isolation. We used the SpyTag/SpyCatcher protein ligase to join these parts together, thereby creating devices with desired properties based on summed properties of parts and in configurations that cannot be obtained by using genetic engineering. This strategy will create optimized recombinant antibody devices at reduced costs and with shortened development times.     

Dynamic Profile Monitoring for Flooding Prognosis in Packed Columns

In the chemical industry, real‐time flooding prognosis is a necessity for packed‐column operation because the flooding phenomenon interferes with the performance of production systems. In this work, the profile monitoring technique is utilized to capture the dynamic behavior of pressure drop, which is an important indicator for the flooding phenomenon. In each moving window, the pressure drop signals are described by using an exponential generalized autoregressive conditional heteroskedastic model. The onset of the flooding phenomenon is then indicated by changes in model parameters. Moreover, to efficiently capture the process change, a nonparametric approach is utilized to establish a statistical control chart. Experimental and comparison results show the advantages of the proposed method.     

The death of Chatterton,or photography and the law

Abstract

It seems destiny that all that is connected with the young British poet, Thomas Chatterton, must be filled with controversy. The furore which arose concerning his publication of the Rowley poems was only intensified by the writer's untimely death.     

Thermal stability study of a new guanidine suppressor for the next-generation caustic-side solvent extraction process

Cesium stripping performance of thermally stressed solvent worsens slowly over time in batch tests of the Next-Generation Caustic-Side Solvent Extraction (NG-CSSX) process. NG-CSSX is currently used in full-scale equipment at the Savannah River Site for the selective removal of caesium from high-level salt waste. Recently, a new guanidine, N,N’,N”-tris(3,7-dimethyloctyl)guanidine (TiDG), was chosen for use as the suppressor, a lipophilic organic base needed for stripping, and the present study was undertaken to address the question of its stability. The NG-CSSX process solvent was evaluated for a period of three months under a variety of temperature and storage conditions. The performance of the solvent was tested at 30-day increments using an extraction, scrub, strip and extraction (ES₂S₃E) sequence. The results provide insights into the effects of storage and process conditions, the stripping behaviour of TiDG and the stability of the new solvent composition.     

Bridging the Gap between Quantitative and Qualitative Accelerated Life Tests

Test planners have long sought the ability to incorporate the results of highly accelerated life testing (HALT) into an early estimate of system reliability. While case studies attest to the effectiveness of HALT in producing reliable products, the capability to translate the test's limited failure data into a meaningful measure of reliability improvement remains elusive. Further, a review of quality and reliability literature indicates that confusion exists over what defines a HALT and how HALT differs from quantitative accelerated life testing methods. Despite many authors making a clear distinction between qualitative and quantitative accelerated life tests, an explanation as to why this delineation exists cannot be found. In this paper, we consider an exemplary HALT composed of a single stressor to show that the HALT philosophy precludes the estimation of a system's hazard rate function parameters because of the test's fix implementation strategy. Four common accelerated failure data analysis methods are highlighted to show their limitations with respect to estimating reliability from HALT data. Finally, a modified accelerated reliability growth test is proposed as a way forward for future research in HALT scenarios to characterize the risk of attaining a reliability requirement and improve parameter estimation. Copyright © 2014 John Wiley & Sons, Ltd.