吐哈盆地英1井西山窑组砂岩中沥青的荧光特征及成因

吐哈盆地台南凹陷吐玉克稠油油田北侧钻探的英1井,在中侏罗统西山窑组取心见到了少量含沥青砂岩。笔者利用荧光显微镜对沥青产状及荧光特征进行观察描述,结合区域地质条件的分析研究,得出了砂岩中的沥青是经过剥蚀搬运后再沉积的结论     

Use of the Weibull model for lactococcal bacteriophage inactivation by high hydrostatic pressure

Four lactococcal bacteriophages (phiLl6-2, phiLl35-6, phiLd66-36 and phiLd67-42) in M17 broth were pressurized at 300 and 350 MPa at room temperature and their survival curves were determined at various time intervals. Tailing (monotonic upward concavity) was observed in all survival curves. The resulting non-linear semi-logarithmic survival curves were described by the Weibull model and goodness of fit of this model was investigated. Regression coefficients (R2), root mean square error (RMSE), residual and correlation plots strongly suggested that Weibull model produced a better fit to the data than the traditional linear model. Hazard plots suggested that the Weibull model was fully appropriate for the data being analyzed. These results have confirmed that the Weibull model, which is mostly utilized to describe the inactivation of bacterial cells or spores by heat and pressure, could be successfully used in describing the lactococcal bacteriophage inactivation by high hydrostatic pressure.     

三塘湖盆地马朗凹陷卡拉岗组火山岩油藏主控因素及勘探方向

为了搞清三塘湖盆地马朗凹陷上石炭统卡拉岗组火山岩油藏成因和分布,从分析火山岩油藏地质特征和控制油藏形成的因素入手,指出火山岩岩相、优质烃源岩、断裂和不整合是油藏形成的主控因素。上石炭统哈尔加乌组优质烃源岩为卡拉岗组火山岩储层提供了充足油源;不整合和广泛发育的断裂不仅为火山岩储层形成提供了条件,同时也是下部油气向上运移的通道。下步油气勘探应在二叠系条湖组剥蚀线和上石炭统卡拉岗组剥蚀线之间近水体的火山岩风化壳发育区展开,有利区带为牛东东南缘、马北构造带和马东构造带。     

A DEA approach for comparing solution efficiency in U-line balancing problem using goal programming

Line balancing problem plays an important role in the decision making process to increase efficiency and productivity. Recently, U-shaped layout in many production lines has replaced the traditional straight line layout using just-in-time concept. Here, we propose a model, using multi-objective decision making approach to the U-shaped line balancing problem, to offer enhanced decision maker flexibility, by allowing for conflicting goals. The assembly line operation efficiency is the most significant aim in our study, and this efficiency relates to management of resources and the solution of line balancing problem. First, the U-shaped line balancing problem is solved considering the model's goals. Then, the index function of assembly line balancing is determined and the efficiencies of the optimal solution outputs are evaluated using data envelopment analysis (DEA). Finally, the discrimination weakness and distribution of illogical weight in simple DEA models are resolved using a mixed method.     

牛东火山岩油藏岩性识别技术及应用

牛东石炭系火山岩油藏是吐哈油田发现的第一个火山岩油藏,岩性复杂多变,准确识别岩性对储层识别显得尤为重要,也是划分火山岩喷发期次、识别岩相、建立储层参数解释模型、综合评价储层的基础。本文在测井响应特征分析的基础上,结合各种取心、录井资料,分三步建立牛东火山岩岩性识别模式,取得了较好效果,为同类油田进行火山岩岩性识别提供借鉴作用。     

Design and implementation of an adaptive fuzzy sliding mode controller for drug delivery in treatment of vascular cancer tumours and its optimisation using genetic algorithm tool

In this paper, the side effects of drug therapy in the process of cancer treatment are reduced by designing two optimal non‐linear controllers. The related gains of the designed controllers are optimised using genetic algorithm and simultaneously are adapted by employing the Fuzzy scheduling method. The cancer dynamic model is extracted with five differential equations, including normal cells, endothelial cells, cancer cells, and the amount of two chemotherapy and anti‐angiogenic drugs left in the body as the engaged state variables, while double drug injection is considered as the corresponding controlling signals of the mentioned state space. This treatment aims to reduce the tumour cells by providing a timely schedule for drug dosage. In chemotherapy, not only the cancer cells are killed but also other healthy cells will be destroyed, so the rate of drug injection is highly significant. It is shown that the simultaneous application of chemotherapy and anti‐angiogenic therapy is more efficient than single chemotherapy. Two different non‐linear controllers are employed and their performances are compared. Simulation results and comparison studies show that not only adding the anti‐angiogenic reduce the side effects of chemotherapy but also the proposed robust controller of sliding mode provides a faster and stronger treatment in the presence of patient parametric uncertainties in an optimal way. As a result of the proposed closed‐loop drug treatment, the tumour cells rapidly decrease to zero, while the normal cells remain healthy simultaneously. Also, the injection rate of the chemotherapy drug is very low after a short time and converges to zero.     

牛东区块石炭系C_2k火山岩油藏试采特征分析

三塘湖盆地牛东区块上石炭统卡拉岗组（C2k）油藏为吐哈油田首次发现的裂缝一孔隙型火山岩油藏，其储层岩性识别、岩相划分、渗流机理、井网部署与开发规律是吐哈开发工作者面临的全新课题，技术难点较多。系统总结试采特征，深入分析试采产量变化原因，对于制定合理开发技术政策，实现科学高效开发具有十分重要的指导意义。     

牛东区块卡拉岗组火山岩油藏岩性岩相特征

根据岩石化学成分分析、薄片鉴定、岩心观察以及测井标定与识别，将三塘湖盆地牛东区块卡拉岗组火山岩分为熔岩和火山碎屑岩两大类，在此基础上，初步尝试地质、测井和地震结合研究火山岩岩相，将火山岩岩相划分为爆发相、喷溢相和火山沉积相三大类。探讨火山岩性岩相对储集性能及含油性的控制作用。     

Stem cell isolation

High-dose chemotherapy with autologous hematopoietic progenitor cell support is increasingly used to treat a variety of malignant diseases. A drawback of this technique is the potential for infusing clonogenic tumor cells with the autograft, producing relapse of the disease in the patient. The use of positive selection techniques to isolate stem cells and thus reduce or eliminate tumor cell contamination has been extensively studied over the past few years. Preliminary clinical results have demonstrated that these procedures deplete 2 to 7 logs of tumor cells and do not impair engraftment. It is too early to assess the ultimate clinical benefit of this strategy. Additional applications of CD34-selection include ex vivo expansion of and gene transfer into hematopoietic progenitor cells and T-cell depletion of allogeneic grafts to reduce the incidence of graft-versus-host disease.     

Metamodel assisted evolution strategies for global optimization of solder joints reliability in embedded mechatronic devices

Microsystem Technologies - This paper proposes a Kriging assisted covariance matrix adaptation evolution strategy (AK-CMA-ES) for optimization of mechatronics device structures. The objective of...