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91.
92.
Nader Tehrani Dan Gallagher Monica Ponce de Leon Harry Lowd Richard Lee Lisa Huang Remon Alberts Janghwan Cheon Jumanah Jamal Aishah Al Sager 《世界建筑导报》2018,(2)
正Banq餐厅位是一家新型餐厅,位于便士储蓄银行(Penny Savings Bank)旧大楼以前用来经营银行业务的大厅内。餐厅分成两个部分,前面区域面向华盛顿大街,设计成酒吧,后面的大厅则作为用餐区。然而,这个空间在z轴上以天花板和地面之间的另一个分区为中心进行设计。如果由于餐厅空间活动的多变性而需要保持灵活性——包括两个座位、四个座位和六个座位,以及与聚会和其他活动有关的座位 相似文献
93.
94.
Heather A. Doty Megan R. Leedy Harry S. Courtney Warren O. Haggard Joel D. Bumgardner 《Journal of materials science. Materials in medicine》2014,25(6):1449-1459
A biodegradable, composite bone graft, composed of chitosan microspheres embedded in calcium sulfate, was evaluated in vitro for point-of-care loading and delivery of antibiotics and growth factors to prevent infection and stimulate healing in large bone injuries. Microspheres were loaded with rhBMP-2 or vancomycin prior to mixing into calcium sulfate loaded with vancomycin. Composites were evaluated for set time, drug release kinetics, and bacteriostatic/bactericidal activity of released vancomycin, induction of ALP expression by released rhBMP-2, and interaction of drugs on cells. Results showed the composite set in under 36 min and released vancomycin levels that were bactericidal to S. aureus (>MIC 8–16 μg/mL) for 18 days. Composites exhibited a 1 day-delayed release, followed by a continuous release of rhBMP-2 over 6 weeks; ranging from 0.06 to 1.49 ng/mL, and showed a dose dependent release based on initial loading. Released rhBMP-2 levels were, however, too low to induce detectable levels of ALP in W20-17 cells, due to the affinity of rhBMP-2 for calcium-based materials. With stimulating amounts of rhBMP-2 (>50 ng/mL), the ALP response from W-20-17 cells was inhibited when exposed to high vancomycin levels (1,800–3,600 μg/mL). This dual-delivery system is an attractive alternative to single delivery or preloaded systems for bone regeneration since it can simultaneously fight infection and deliver a potent growth factor. Additionally, this composite can accommodate a wide range of therapeutics and thus be customizable for specific patient needs, however, the potential interactive effects of multiple agents must be investigated to ensure that functional activity is not altered. 相似文献
95.
The design of many thermal Microelectromechanical (MEMS) actuators is often based on finite element analysis, but lacks analytical
insight. In this paper we report a novel electro-thermal microgripper and a comprehensive thermal modeling of a general 5
lineshape microbeam’s actuator using 1-D steady state heat equations. Because of the variety of microgripper fabrication technologies
and their applications, different thermal boundary conditions are considered for lifted off and attached grippers. Parametric
and nonparametric electrothermomechanical identification models for silicon on insulator microgripper, fabricated on 100 μm
device layer, are obtained. 相似文献
96.
Branching rates and growth functions in the outgrowth of dendritic branching patterns 总被引:2,自引:0,他引:2
The outgrowth of dendritic branching patterns proceeds by neurite elongation and branching. These actions are supported by growth cones, specialized dynamic structures at the tips of outgrowing neurites, in response to a multitude of intracellular and extracellular signals and mechanisms. Branching rates of growth cones and their temporal patterns thus reflect the extent and changes in these responses. The present study outlines a model framework to relate branching rates of individual growth cones with the growth rate of the entire dendritic tree. The branching rate of an individual growth cone is assumed to depend on the total number of growth cones at any given moment (representing competition between growth cones), on its position along the dendrite, and on a baseline component representing all other factors. Four different strategies are discussed for determining quantitatively these components from experimental data. The methods are applied in the analysis of dendritic trees of Wistar rat multipolar non-pyramidal neurons, quantitatively reconstructed at several developmental stages (Parnavelas J G and Uylings H B M 1980 Brain Res. 193 373-82, Uylings H B M, Parnavelas J G, Walg H and Veltman W A M 1980 Mikroskopie 37 220-4). It is shown that the baseline branching rate is a rapidly decreasing function of time, indicating the largest baseline drive for branching in the early days of outgrowth. 相似文献
97.
Harry K.H. Chow King Lun Choy W.B. Lee K.C. Lau 《Expert systems with applications》2006,30(4):561-576
In the past, the selection of resources to execute various warehouse operation services was done solely by experts. In this paper, a RFID-based Resource Management System (RFID-RMS) is designed to help users to select the most suitable resource usage packages for handling warehouse operation orders by retrieving and analysing useful knowledge from a case-based data warehouse for solutions in both time saving and cost effective manner. In addition, a pure integral-linear programming model using a branch and bound algorithm to define the optimum travel distance of forklifts is also developed and embedded in the proposed system. The proposed system, which is suitable for usage in a warehouse operation environment, enhances the effectiveness in formulating resource usage package and managing resource operation by integrating the Radio Frequency Identification (RFID), case-based reasoning (CBR) technologies and the programming model for forklift route optimization. Through applying RFID-RMS in the GENCO Distribution System, a multinational logistics company, the utilization of warehouse resources is expected to be maximized while work efficiency will be greatly enhanced. 相似文献
98.
Klesges Robert C.; DeBon Margaret; Vander Weg Mark W.; Haddock C. Keith; Lando Harry A.; Relyea George E.; Peterson Alan L.; Talcott G. Wayne 《Canadian Metallurgical Quarterly》2006,74(2):295
The authors evaluated the effect of a brief tailored smoking control intervention delivered during basic military training on tobacco use in a population of military personnel (N = 33,215). Participants were randomized to either a tobacco use intervention (smoking cessation, smokeless tobacco use cessation, or prevention depending on tobacco use history) or a health education control condition. Results indicated that smokers who received intervention were 1.16 (95% confidence interval [CI] = 1.04, 1.30) times (7-day point prevalence) and 1.23 (95% CI = 1.07, 1.41) times (continuous abstinence) more likely to be abstinent than controls from smoking cigarettes at the 1-year follow-up (p p 相似文献
99.
Bolger Niall; Shrout Patrick E.; Green Amie S.; Rafaeli Eshkol; Reis Harry T. 《Canadian Metallurgical Quarterly》2006,11(1):123
The authors review commentaries by J. E. Broderick and A. A. Stone (2006)(see record 2006-03820-007); H. Tennen, G. Affleck, J. C. Coyne, R. J. Larsen, and A. DeLongis (2006)(see record 2006-03820-008); and M. K. T. Takarangi, M. Garry, and E. F. Loftus (2006)(see record 2006-03820-009) on their original article (A. S. Green, E. Rafaeli, N. Bolger, P. Shrout, & H. T. Reis, 2006)(see record 2006-03820-006). The authors were pleased to find more agreement than disagreement regarding the choice of methods for conducting diary studies. It is clear that continued critical evaluation of all diary methods, both paper and plastic, is warranted. However, on the basis of their initial findings, the authors conclude that paper diaries are still likely to have a valuable place in researchers' toolboxes. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
100.
Frido E. Smulders Harry Boer Poul H.K. Hansen Ebbe Gubi Kees Dorst 《Creativity & Innovation Management》2002,11(1):62-73
This paper describes and illustrates different configurations of the interface between new product development and production processes, including both intra–firm and inter–firm interfaces. These configurations are partly based on a process view of product innovation and partly on a structural view of product innovation. In addition to this typology of interfaces some integration mechanisms are described. The typology will serve as a basis for further research aimed at identifying consistent configurations of the different types of integration mechanisms that are available for industry to increase the effectiveness and efficiency of product innovation processes. 相似文献