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81.
Yukitoshi Takeshita Takao Handa Hayato Minami Shinichi Niwa Keiichiro Sugimoto 《Polymer Engineering and Science》2010,50(11):2258-2272
We have been developing a new optical wiring technology for installing indoor optical fiber cables directly into apartment houses for fiber to the home. The technology must minimize the friction of optical fiber cable. We reviewed many studies on friction behavior, and studied the friction properties of a wide variety of polymer sheets and optical fiber cables, and considered the friction mechanism. Relatively, soft polymer materials exhibited stick‐slip behavior and the hard polymers exhibited constant slip behavior. Lubricants are effective in reducing friction and play a dominant role as regards the friction property. Silicon and fluorocarbon agents play some role in converting the stick‐slip characteristic into constant slip behavior. A certain roughness is effective in reducing friction. POLYM. ENG. SCI., 2010. © 2010 Society of Plastics Engineers. 相似文献
82.
Yoshihide Usami Hayato Ichikawa Masao Arimoto 《International journal of molecular sciences》2008,9(3):401-421
Pericosines are unique C7 cyclohexenoid metabolites of Periconia byssoides OUPS-N133 fungus that was originally isolated from the sea hare, Aplysia kurodai. Pericosines show significant in vitro cytotoxicity against P388 lymphocytic leukemia cells. Pericosine A, in particular, shows the most potent activity and significant in vivo antitumor activity against P388 cells. Thus, pericosines are promising candidates for seed compounds of anticancer drugs. However, before the total syntheses of pericosines were accomplished, their stereo structures could not be determined by spectral analyses because they have multi-functionalized cyclohexenoid structures with torsional strain. In this review, synthetic efforts for pericosines in this decade are surveyed. 相似文献
83.
Yttrium niobate YNbO4 nanocrystals with ellipsoidal morphology were directly formed from the precursor solution mixtures of YCl3 and NbCl5 under weakly basic conditions in the presence of aqueous ammonia by hydrothermal method. The hydrothermal treatment at 180°C for 5 h was necessary to obtain nanocrystals (18 nm) with sufficient crystallinity. The optical band gap of the as‐prepared samples was 3.6 eV. The as‐prepared YNbO4 nanocrystals showed UV‐blue and broadband emission centered at 405 nm under excitation at 235 nm, which was due to the blue recombination luminescence, associated with charge‐transfer transitions involving the tetrahedral NbO4 group. The emission intensity increased with increased hydrothermal treatment temperature. The photoluminescence intensity of the YNbO4 was extremely improved via heating above 1000°C in air, which was accompanied by the increase in the optical band gap from 3.6 to 4.0 eV. By heat treatment at 1300°C, the intensity of the UV‐blue and broadband emission (with maximum at 400 nm) for the YNbO4 became more than 22.5 times as strong as that before heat treatment. 相似文献
84.
Toshiharu Kazama Hayato Sasaki Yukihito Narita 《Journal of Mechanical Science and Technology》2010,24(1):203-206
Temperatures of three bearing and seal parts of a swash plate type axial piston pump were measured simultaneously using a
slip ring with thermocouples’ amplifiers. The rotating cylinder block had five thermocouples, the swash-plate had four, and
the valve-plate had four. Three sets of pistons with different diameters were prepared. Hydraulic mineral oil with VG22 and
a water-glycol type hydraulic oil with VG32 were used as test fluids. The maximum discharge pressure was 20 MPa; the maximum
rotational speed was 25 rps. The inlet oil temperature was 20–40°C. Temperatures and temperature differences between the bottom-dead-center
and the top-dead-center increased concomitantly with the discharge pressure. For larger piston clearance ratios, the temperatures
rose monotonically. The bearing and seal parts were markedly hotter than the discharge oil. Temperatures rose much less using
the water-glycol type oil than when using the mineral oil. 相似文献
85.
海苔发酵提取物对原发性高血压大鼠的降压效果研究 总被引:1,自引:0,他引:1
使用可以产生GABA的植物性乳酸菌对海苔进行发酵,得到富含10.5%GABA的海苔发酵提取物。本实验验证了海苔发酵提取物对原发性高血压模型大鼠(SHR)的降压效果。单次经口灌胃给药实验中,分别以2mg/kg·bw和0.2mg/kg·bw剂量的海苔发酵提取物一次性灌胃给药,给药后2、5、9、24h进行血压测定。结果表明,海苔发酵提取物2mg/kg·bw剂量组在给药后5h和24h均有显著降压效果(p<0.05,p<0.01)。长期摄食给药实验中,含有海苔发酵提取物0.001%和0.003%的饲料剂量组对成长期SHR和老龄期SHR分别摄食给药,给药后每2~3d进行一次血压和体重测量,结果显示含有海苔发酵提取物0.003%的饲料剂量组使成长期SHR和老龄期SHR血压均显著下降(p<0.01,p<0.05)。 相似文献
86.
Yamada S. Hayato Y. Obayashi Y. Shiozawa M. 《IEEE transactions on nuclear science》2008,55(2):683-686
An online system of the underground neutrino detector, Super-Kamiokande is scheduled to be upgraded in 2008 together with front-end electronics. This detector consists of 50 000 tons of pure water equipped with about 13 000 photo-multipliers (PMTs) to detect Cherenkov light. The new online system is required to accept the dataflow of up to 800 MB/s from the front-end electronics and process them for the offline analysis. We will utilize a Gigabit Ethernet network and parallel data processing to handle this large amount of flow. In the new data acquisition scheme, we will not use a hardware event-trigger but read out every hit data from the front-end electronics and process them by the online farm. Therefore, there is no threshold of the number of PMT hits and the detector will become more sensitive to important cosmic-ray events such as relic neutrino from supernova and low energy solar neutrino. In addition to that, a dead-timeless system is desirable for the continuous measurement 365 days a year. In this paper, the detailed design of the upgraded online system and testing activities using prototypes will be described. 相似文献
87.
88.
Photocatalytic oxidation of various organic compounds by using molecular oxygen has been broadly investigated as a valuable synthetic route, but the application has been still limited because the active oxygen species from the molecular oxygen are usually difficult to be controlled. In this short review, we describe two kinds of photocatalytic oxygenation with H2O molecule as a source of OH group; i.e., photocatalytic hydroxylation of aromatic ring and photocatalytic hydration of alkene, on Pt/TiO2 photocatalyst. In both reactions, a photoformed active oxygen species attacks to the sp2-carbon to form a reaction intermediate. In the aromatic ring hydroxylation, the elimination of the H atom from the intermediate proceeds while the conjugate double bond of the aromatic ring maintains. In the alkene hydration, the addition of the H radical to the intermediate results in forming an alcohols molecule with the saturation of the double bond. In the former case, the electrophilic property of the active oxygen species predominantly determines the orientation of the OH group in the produced phenols. On the other hand, in the latter case, the thermodynamic stability of the intermediate radical species leads the active oxygen species preferentially to the terminal sp2-carbon, which makes it possible to provide the unique regioselectivity of alcohol according to the anti-Markovnikov rule. 相似文献
89.
Hayato Akimoto Minoru Sugihara Shigeru Hishinuma 《International journal of molecular sciences》2021,22(4)
Bilastine, a zwitterionic second-generation antihistamine containing a carboxyl group, has higher selectivity for H1 receptors than first-generation antihistamines. Ligand-receptor docking simulations have suggested that the electrostatic interaction between the carboxyl group of second-generation antihistamines and the amino group of Lys179ECL2 and Lys1915.39 of human H1 receptors might contribute to increased affinity of these antihistamines to H1 receptors. In this study, we evaluated the roles of Lys179ECL2 and Lys1915.39 in regulating the electrostatic and hydrophobic binding of bilastine to H1 receptors by thermodynamic analyses. The binding enthalpy and entropy of bilastine were estimated from the van ’t Hoff equation using the dissociation constants. These constants were obtained from the displacement curves against the binding of [3H] mepyramine to membrane preparations of Chinese hamster ovary cells expressing wild-type human H1 receptors and their Lys179ECL2 or Lys1915.39 mutants to alanine at various temperatures. We found that the binding of bilastine to wild-type H1 receptors occurred by enthalpy-dependent binding forces and, more dominantly, entropy-dependent binding forces. The mutation of Lys179ECL2 and Lys1915.39 to alanine reduced the affinity of bilastine to H1 receptors by reducing enthalpy- and entropy-dependent binding forces, respectively. These results suggest that Lys179ECL2 and Lys1915.39 differentially contribute to the increased binding affinity to bilastine via electrostatic and hydrophobic binding forces. 相似文献
90.
Zadid Khan Sakib Mahmud Khan Mashrur Chowdhury Ilya Safro Hayato Ushijima‐Mwesigwa 《Computer-Aided Civil and Infrastructure Engineering》2019,34(7):547-568
This study presents the Wireless Charging Utility Maximization (WCUM) framework, which aims to maximize the utility of Wireless Charging Units (WCUs) for electric vehicle (EV) charging through the optimal WCU deployment at signalized intersections. Furthermore, the framework aims to minimize the control delay at all signalized intersections of the network. The framework consists of a two‐step optimization formulation, a dynamic traffic assignment model to calculate the user equilibrium, a traffic microsimulator to formulate the objective functions, and a global Mixed Integer Non‐Linear Programming (MINLP) optimization solver. An optimization problem is formulated for each intersection, and another for the entire network. The performance of the WCUM framework is tested using the Sioux Falls network. We perform a comparative study of 12 global MINLP solvers with a case study. Based on solution quality and computation time, we choose the Couenne solver for this framework. 相似文献