Clinical comparison of radiolocalization of two monoclonal antibodies (mAbs) against the TAG-72 antigen

Ten patients with colorectal cancer metastases received 125I-B72.3 and 131I-CC49 prior to laparotomy (five patients received 1 mg, and five 20 mg of each mAb). Tumor:serum ratios of 131I-CC49 were better than those of 125I-B72.3 (P < 0.01 at 1 mg; P = 0.05 at 20 mg; P < 0.01 at both doses). All known lesions > or = 1 cm in diameter were visualized at the 20 mg dose. There was no difference in absolute tumor uptake of 125I-B72.3 or 131I-CC49. We conclude that mAb CC49 has better relative uptake in colorectal cancers than mAb B72.3.     

Use of chemical assessment of quality in the economics of tea production in Malawi

The effect of nitrogen fertiliser application on the price of teas made in Malawi is quantified through the intermediate relationships of applied nitrogen upon shoot flavanol composition, and between manufactured tea theaflavin content and price. Combining the effect of fertiliser on price and yield allows estimates of the economically optimum level of application to be made. The effects of variations in physical relationships and of prices of tea and fertiliser are assessed.     

Load behaviour prediction under blackout conditions using a fuzzy expert system

This paper proposes a method to forecast load behaviour during restoration of power systems after total or partial blackouts. Load behaviour after blackouts can be anomalous and differ significantly from that during normal operation conditions. A heuristic top-down approach was adopted to develop the forecasting method, using an expert system based on linguistic variables and fuzzy logic rules as its central core. The approach addresses the main aspects of load behaviour during re-energisation and is capable of representing physical phenomena. The proposed methodology was tested with data from real electrical power substations and these test results are presented     

Time-Resolved Temperature Measurement of AlGaN/GaN Electronic Devices Using Micro-Raman Spectroscopy

We report on the development of time-resolved Raman thermography to measure transient temperatures in semiconductor devices with submicrometer spatial resolution. This new technique is illustrated for AlGaN/GaN HFETs and ungated devices grown on SiC and sapphire substrates. A temporal resolution of 200 ns is demonstrated. Temperature changes rapidly within sub-200 ns after switching the devices on or off, followed by a slower change in device temperature with a time constant of ~10 and ~140 mus for AlGaN/GaN devices grown on SiC and sapphire substrates, respectively. Heat diffusion into the device substrate is also demonstrated     

Heterogeneous InSb quantum well transistors on silicon for ultra-high speed, low power logic applications

The heterogeneous integration of InSb quantum well transistors onto silicon substrates is investigated for the first time. 85 nm gate length FETs with f_T = 305 GHz at V_ds = 0.5 V and DC performance suitable for digital logic are demonstrated on material with a buffer just 1.8 mum thick. An initial step towards integrating InSb FETs with mainstream Si CMOS for high-speed energy-efficient logic applications has been achieved.     

A framework for network quality monitoring in the VoIP environment

Monitoring speech quality in Voice over IP (VoIP) networks is important to ensure a minimal acceptable level of speech quality for IP calls running through a managed network. Information such as packet loss, codec type, jitter, end‐to‐end delay and overall speech quality enables the network manager to verify and accurately tune parameters in order to adjust network problems. The present article proposes the deployment of a monitoring architecture that collects, stores and displays speech quality information about concluded voice calls. This architecture is based on our proposed MIB (Management Information Base) VOIPQOS, deployed for speech quality monitoring purposes. Currently, the architecture is totally implemented, but under adjustment and validation tests. In the future, the VOIPQOS MIB can be expanded to automatically analyze collected data and control VoIP clients and network parameters for tuning the overall speech quality of ongoing calls. Copyright © 2006 John Wiley & Sons, Ltd.     

Non‐Volatile ReRAM Devices Based on Self‐Assembled Multilayers of Modified Graphene Oxide 2D Nanosheets

2D nanomaterials have been actively utilized in non‐volatile resistive switching random access memory (ReRAM) devices due to their high flexibility, 3D‐stacking capability, simple structure, transparency, easy fabrication, and low cost. Herein, it demonstrates re‐writable, bistable, transparent, and flexible solution‐processed crossbar ReRAM devices utilizing graphene oxide (GO) based multilayers as active dielectric layers. The devices employ single‐ or multi‐component‐based multilayers composed of positively charged GO (N‐GO(+) or NS‐GO(+)) with/without negatively charged GO(‐) using layer‐by‐layer assembly method, sandwiched between Al bottom and Au top electrodes. The device based on the multi‐component active layer Au/[N‐GO(+)/GO(‐)]_n/Al/PES shows higher ON/OFF ratio of ≈10⁵ with switching voltage of ?1.9 V and higher retention stability (≈10⁴ s), whereas the device based on single component (Au/[N‐GO(+)]_n/Al/PES) shows ≈10³ ON/OFF ratio at ±3.5 V switching voltage. The superior ReRAM properties of the multi‐component‐based device are attributed to a higher coating surface roughness. The Au/[N‐GO(+)/GO(–)]_n/Al/PES device prepared from lower GO concentration (0.01%) exhibits higher ON/OFF ratio (≈10⁹) at switching voltage of ±2.0 V. However, better stability is achieved by increasing the concentration from 0.01% to 0.05% of all GO‐based solutions. It is found that the devices containing MnO₂ in the dielectric layer do not improve the ReRAM performance.     

Cumulative impact assessment on air quality from multiple open pit mines

Both open pit mine and smelter projects can have significant impacts on a variety of environmental resources. Among these, air quality of the surroundings is a key issue. Additionally, the environmental assessment of projects demands integrated approach taking in account all pollution sources. Therefore, specific focus has been put on the methodology for assessing impacts on air quality. This paper proposes an integrated index of environmental impact aiming to quantify the air quality impact of industrial operations around an urban area, in case of scarcity of in situ acquired data. This proposed pollution index is demonstrated by a case study conducted in the municipality of Congonhas, Brazil, in which contributions of five open pit mines and two smelters were studied. To achieve the pollution index, the wind rose and distances from the centroids of effective areas to the urban nucleus itself were considered, taking into account the wind projection areas from windward impacting sources on the leeward impacted urban site. The proposed index also includes the squared wind speed (proportional to the kinetic energy transferred in uplifting dust from ground surface). The method proposed is considered suitable for impact assignment for each one of the air pollution sources in the neighborhood of studied area. Some fluid dynamic aspects of airborne particulate matter are also studied by proposing a new equation for threshold saltation speed.     

3D Scene Reconstruction from Multiple Spherical Stereo Pairs

We propose a 3D environment modelling method using multiple pairs of high-resolution spherical images. Spherical images of a scene are captured using a rotating line scan camera. Reconstruction is based on stereo image pairs with a vertical displacement between camera views. A 3D mesh model for each pair of spherical images is reconstructed by stereo matching. For accurate surface reconstruction, we propose a PDE-based disparity estimation method which produces continuous depth fields with sharp depth discontinuities even in occluded and highly textured regions. A full environment model is constructed by fusion of partial reconstruction from spherical stereo pairs at multiple widely spaced locations. To avoid camera calibration steps for all camera locations, we calculate 3D rigid transforms between capture points using feature matching and register all meshes into a unified coordinate system. Finally a complete 3D model of the environment is generated by selecting the most reliable observations among overlapped surface measurements considering surface visibility, orientation and distance from the camera. We analyse the characteristics and behaviour of errors for spherical stereo imaging. Performance of the proposed algorithm is evaluated against ground-truth from the Middlebury stereo test bed and LIDAR scans. Results are also compared with conventional structure-from-motion algorithms. The final composite model is rendered from a wide range of viewpoints with high quality textures.