Thermal MIMO controller for setpoint regulation and load disturbance rejection

The thermal interaction problem of a multi-input multi-output (MIMO) temperature process is caused by the temperature gradient through the plant. Generally, industrial controllers are used for the decentralized control and do not use a process mathematical model. In many cases, trial-and-error tuning is required for solving the problem. The present paper introduces a MIMO thermal model and the decoupling PID control strategy. The decoupling control and its shortcomings are described from the perspective of the user. An improved strategy based on a robust observer is developed. For industrial implementation, this observer is quite simple because only the first-order model given by the decoupling model is implemented. The program code is simple for the microprocessor of a low-cost commercialized controller. In addition, a hunting rejection method based on the observer is presented. The present paper applies the method to the twin screw extruder in order to verify the effectiveness of the proposed strategy. The proposed method has been successfully to solve the interaction problem for MIMO temperature process.     

Design parameter evaluation based on human operation for tip mechanism of forceps manipulator using surgical robot simulation

We proposed a design method for pediatric surgical robots that evaluates the workspace and view information in computer simulator before the actual robot is developed. In this study, we investigated a suturing task in a virtual environment using forceps manipulators with different mechanical parameters. We reproduced the surgical workspace for congenital esophageal atresia and measured the working volume and invisible area to obtain suitable parameters for the suturing task. We also calculated the suitable mechanical parameters using Pareto optimal solution method and verified the mechanical parameters in Pareto optimal solution. We verified from the experimental results that there is a trade-off between the working volume and invisible area during the suturing task. Moreover, we determined from the calculation results that the mechanical design of the forceps manipulator is influenced by the invisible area during the suturing task. Finally, we confirmed that it is possible to obtain suitable parameters for surgical robots using the proposed method.     

A High-Performance, Pipelined, FPGA-Based Genetic Algorithm Machine

Accelerating a genetic algorithm (GA) by implementing it in a reconfigurable field programmable gate array (FPGA) is described. The implemented GA features: random parent selection, which conserves selection circuitry; a steady-state memory model, which conserves chip area; survival of fitter child chromosomes over their less-fit parent chromosomes, which promotes evolution. A net child chromosome generation rate of one per clock cycle is obtained by pipelining the parent selection, crossover, mutation, and fitness evaluation functions. Complex fitness functions can be further pipelined to maintain a high-speed clock cycle. Fitness functions with a pipeline initiation interval of greater than one can be plurally implemented to maintain a net evaluated-chromosome throughput of one per clock cycle. Two prototypes are described: The first prototype (c. 1996 technology) is a multiple-FPGA chip implementation, running at a 1 MHz clock rate, that solves a 94-row × 520-column set covering problem 2,200× faster than a 100 MHz workstation running the same algorithm in C. The second prototype (Xilinx XVC300) is a single-FPGA chip implementation, running at a 66 MHZ clock rate, that solves a 36-residue protein folding problem in a 2-d lattice 320× faster than a 366 MHz Pentium II. The current largest FPGA (Xilinx XCV3200E) has circuitry available for the implementation of 30 fitness function units which would yield an acceleration of 9,600× for the 36-residue protein folding problem.     

Flexible color LCD panel driven by low‐voltage‐operation organic TFT

Abstract— A flexible color LCD panel driven by organic TFTs (OTFTs) was successfully demonstrated. A pentacene OTFT with an anodized Ta₂O₅ gate insulator, which can be operated at low voltage, was developed. In order to improve the electrical performance of the OTFT, the gate insulator was surface treated by processes such as O₂ plasma, UV light irradiation, and hexamethyldisilane treatments. The fabricated OTFT exhibited a mobility of 0.3 cm²/V‐sec and a current on/off ratio of 10⁷ with a low operating drain voltage of ?5 V. A fast‐response‐time flexible ferroelectric LCD, which contains polymer networks and walls, was integrated with the OTFTs by using a lamination and a printing technique. As a result, color images were achieved on the fabricated panel by using a field‐sequential‐color method at a low driving voltage of less than 15 V_pp.     

LIF imaging of OH radicals in DC positive streamer coronas

In this study, the LIF detection of the hydroxyl (OH) radicals was performed in a nozzle-to-plane electrode system having an electrode gap of 30 mm during the steady-state positive streamer corona discharge at atmospheric pressure. For monitoring the ground-state OH radicals, OH transition [A² Σ⁺(v′ = 1) ← X²Π(v″ = 0)] at 282 nm was used. The time relationship between the regular streamer coronas, laser pulse, OH fluorescence and laser-induced streamer was measured. The time dependence of OH radicals between the successive streamers was measured for the evaluation of OH dynamics when the discharge was in a steady-state condition. The two-dimensional OH distribution in the DC streamer corona discharge was observed. The obtained results showed that the ground-state OH radicals were generated mainly in the filamentary part of the streamers. It was found that LIF detectable amount of ground-state OH radicals stayed in the region where streamers propagate during the steady-state DC positive streamer corona in open air.     

Cancer Malignancy Is Correlated with Upregulation of PCYT2-Mediated Glycerol Phosphate Modification of α-Dystroglycan

The dystrophin–glycoprotein complex connects the cytoskeleton with base membrane components such as laminin through unique O-glycans displayed on α-dystroglycan (α-DG). Genetic impairment of elongation of these glycans causes congenital muscular dystrophies. We previously identified that glycerol phosphate (GroP) can cap the core part of the α-DG O-glycans and terminate their further elongation. This study examined the possible roles of the GroP modification in cancer malignancy, focusing on colorectal cancer. We found that the GroP modification critically depends on PCYT2, which serves as cytidine 5′-diphosphate-glycerol (CDP-Gro) synthase. Furthermore, we identified a significant positive correlation between cancer progression and GroP modification, which also correlated positively with PCYT2 expression. Moreover, we demonstrate that GroP modification promotes the migration of cancer cells. Based on these findings, we propose that the GroP modification by PCYT2 disrupts the glycan-mediated cell adhesion to the extracellular matrix and thereby enhances cancer metastasis. Thus, the present study suggests the possibility of novel approaches for cancer treatment by targeting the PCYT2-mediated GroP modification.     

Effect of Different Molecular Weights of Polyacrylic Acid on Rat Lung Following Intratracheal Instillation

Background: We conducted intratracheal instillations of different molecular weights of polyacrylic acid (PAA) into rats in order to examine what kinds of physicochemical characteristics of acrylic acid-based polymer affect responses in the lung. Methods: F344 rats were intratracheally exposed to a high molecular weight (HMW) of 598 thousand g/mol or a low molecular weight (LMW) of 30.9 thousand g/mol PAA at low and high doses. Rats were sacrificed at 3 days, 1 week, 1 month, 3 months and 6 months post exposure. Results: HMW PAA caused persistent increases in neutrophil influx, cytokine-induced neutrophil chemoattractants (CINC) in the bronchoalveolar lavage fluid (BALF), and heme oxygenase-1 (HO-1) in the lung tissue from 3 days to 3 months and 6 months following instillation. On the other hand, LMW PAA caused only transient increases in neutrophil influx, CINC in BALF, and HO-1 in the lung tissue from 3 days to up to 1 week or 1 month following instillation. Histopathological findings of the lungs demonstrated that the extensive inflammation and fibrotic changes caused by the HMW PAA was greater than that in exposure to the LMW PAA during the observation period. Conclusion: HMW PAA induced persistence of lung disorder, suggesting that molecular weight is a physicochemical characteristic of PAA-induced lung disorder.     

Boiling behaviors and critical heat flux on a horizontal plate in saturated pool boiling of water at high pressures

Observations of boiling behaviors and measurements of critical heat flux (CHF) were carried out for saturated water boiling on a horizontal, upward-facing plate at pressures from atmospheric to 7 MPa. The primary bubbles diminish in size almost in inverse proportion to pressure and commence to coalesce in the very low heat flux region. The diameter of detached coalesced bubbles increases with increases in the heat flux and reaches about 10 mm even at a pressure of 5 MPa. Detachment frequency of the coalesced bubbles was unaffected by the heat flux and pressure. The CHF predicted based on the macrolayer dryout model agrees well with the measured data.     

Remarks on the assignments of temperature programmed desorption peaks for the surface species formed on Cu/ZnO and ZnO in the methanol synthesis from CO

Temperature programmed desorption (TPD), IR spectroscopy and chemical trapping of the surface species with H₂O revealed that the TPD peak of CO frequently assigned to zinc formate species, which were formed in the course of the methanol synthesis from CO-H₂, arose from zinc methoxide species.