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101.
102.
An array of 1.3 μm FP-LDs with their anodes and cathodes separated channel by channel was developed to suppress interchannel electric crosstalk at high frequency. Low crosstalk of less than -30 dB was obtained between neighbouring LDs at 3.125 GHz. This is sufficiently low that BER characteristics observed under asynchronous operation of a four-channel LD array were found to be no worse than those under single channel operation  相似文献   
103.
To assess the significance of waste dumping sites as a source of chemical contamination to ecosystems, we analyzed the residue levels of polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), polychlorinated biphenyls (PCBs), and other organochlorines in the breast muscle of crows from a dumping site in the south of Chennai city, South India. Crows from the dumping site contained significantly higher total TEQs (60 +/- 27 pg/g lipid wt) than those from the reference sites (26 +/- 18 pg/g lipid wt). Especially, certain dioxin-like coplanar PCB congeners (Co-PCBs), such as CB-77 and CB-105, whose source is commercial PCBs,were significantly higher in crows from the dumping site than those from the reference sites. Profiles of PCDDs/DFs and Co-PCBs in crows from the dumping site were similar to those of soil at the same site, which was confirmed by principal component analysis. Furthermore, significant positive correlations were obtained between the congener-specific bioconcentration factors (BCFs) of PCDDs/DFs estimated from concentrations in crows and soil from the dumping site and the theoretical BCFs calculated from water-particle and lipid-water partitioning coefficients. On the other hand, the estimated BCFs had significant negative correlations with the molecular weight of PCDDs/DFs, indicating that molecular size limits their bioaccumulation. These results suggest that dioxin-like congeners in the soil of the dumping site were transferred directly to the crows through the ingestion of on-site garbage contaminated with soil, rather than through trophic transfer in the ecosystem. The present study provides insight into the ecological impacts of dumping sites.  相似文献   
104.
    
Abstract— An LTPS TFT‐LCD that only consumes 0.07 mW of power was developed. It is the world's first LCD equipped with all the circuits needed to display still images continuously for up to 1 year on a button battery. At the same time, the panel is capable of displaying 260,000‐color moving pictures.  相似文献   
105.
Poly-γ-glutamate (PGA) possesses a nylon-like backbone and polyacrylate-like carboxyl groups, and shows an extraordinary solubility in water. In this study, the effective synthesis and structural analysis of some water-insoluble PGA ion-complexes (PGAICs) using cationic surfactants, hexadecylpyridinium (HDP), dodecylpyridinium, benzalkonium and benzetonium, were examined. We demonstrated their spontaneous coating performance to the surfaces of different materials (i.e., plastics, metals, and ceramics) as potent anti-staphylococcal and anti-Candida agents. The tests against Staphylococcus aureus revealed that, regardless of a variety of materials, PGAICs maintained surface antimicrobial activity, even after the water-soaking treatment, whereas those against Candida albicans indicated that, among PGAICs, PGA/HDP complex is most useful as an anti-fungal agent because of its coating stability. Moreover, the log reduction values against Influenza A and B viruses of PGA/HDP-coated surfaces were estimated to be 5.4 and 3.2, respectively, suggesting that it can be dramatically suppressed the infection of influenza. This is to our knowledge the first observation of PGA-based antiviral coatings.  相似文献   
106.
4S (Super-Safe, Small and Simple) is a small sized sodium-cooled fast reactor being developed for the electricity supply in remote areas, high-temperature steam supply more than 400 °C, seawater desalination, and hydrogen production. The system design of power output of 10 MWe (30 MWt) has been completed. The main feature is that it does not have to be refueled for a long period (i.e. 30 years for 10 MWe version), and enable the reactor closure sealed during plant operation. Furthermore, the small size of the reactor makes the reactor building suitable for below grade installing. These two features can provide resolutions for the issues relevant to safety, security, and safeguard, which become much more serious matter internationally these days.4S is a pool-type reactor which contains the whole primary cooling system in a vessel. For the purpose of reducing the maintenance requirements with the reactor, (1) reflectors to compensate for fuel burn-up instead of control rods, (2) electromagnetic pump (EMP) which has no rotating parts, and (3) residual heat removal system by natural circulation and natural air draft are adopted. Therefore, exchange of the reactor components is not required during plant operation, in addition to no needs for refueling.Toshiba has initiated the U.S. Nuclear Regulatory Commission (NRC) pre-application review of 10 MWe version for the purpose of applying for design approval (DA). A series of public meetings with NRC has been held four times, and five technical reports have been submitted to NRC in preparation for DA application. Topics discussed in these meetings included, plant design, metallic fuel, safety design philosophy, safety analysis, measures against severe accident, phenomena identification and ranking table (PIRT), etc. Some useful comments and questions on the issues regarding the specific feature of 4S as well as sodium-cooled fast reactor were raised by NRC at the public meetings. Among them, those items which are applicable to general sodium-cooled fast reactors, e.g. principal design criteria, guideline for safety analysis, validation and verification for safety analysis code, quality requirements, severe accident, and emergency planning are presented in this paper.  相似文献   
107.
Journal of Computational Electronics - We construct a stochastic classical particle model of an electron taking account of its spin. The behavior of a non-relativistic electron possessing spin is...  相似文献   
108.
Leaf samples of tropical trees, i.e. Dryobalanops lanceolata (Kapur paji), Dipterocarpaceae and Macaranga spp. (Mahang), Euphorbiaceae were analyzed for 21 chemical elements. The pioneer Macaranga spp. exhibited higher concentrations for the majority of elements compared to the emergent species of Dryobalanops lanceolata, which was attributed to the higher physiological activity of the fast growing pioneer species compared to emergent trees. Lead showed rather high concentrations in several samples from the Bakam re-forestation site. This is suggested to be caused by emissions through brick manufacturing and related activities in the vicinity. A comparison of Dryobalanops lanceolata samples collected in 1993, 1995 and 1997 in the Lambir Hills National Park revealed that certain heavy metals, i.e. Co, Cu, Mn, Ni, Pb and Ti showed higher values in 1997 compared to the previous years, which could indicate an atmospheric input from the haze caused by the extensive forest fires raging in Borneo and other parts of Southeast Asia.  相似文献   
109.
    
In this review, we describe previous basic and clinical studies on autonomous aldosterone production. Over the past decades, mineralocorticoid receptor antagonists (MRAs) have been found to concentration-dependently inhibit steroidogenesis in different degrees. However, many studies have proven the suppressive effects of MRAs on the activities of hormone synthase. The probable factors of cytochrome P-450 reduction, both in microsomes and mitochondria, have also been considered: (1) one of the spironolactone metabolite forms had destructive function, except canrenone, (2) 7α-thio-spironolactone was an obligatory intermediate in the spironolactone-induced CYP450 decrease, and (3) the contributing steroids should have 7α-methylthio or 7α-methylsulfone groups. In previous clinical research, spironolactone-body-containing cells showed a type II pattern of enzyme activity (i.e., enhanced 3β-hydroxysteroid dehydrogenase, glucose-6-phosphate, and NADP-isocitrate dehydrogenase activities and weaken succinate dehydrogenase activity), and the subcapsular micronodules composed of spironolactone-body-containing cells also exhibited a type II pattern and excess aldosterone secretion, indicating that the subcapsular micronodules might be the root of aldosterone-producing adenoma. Moreover, combined with the potential impeditive function to aldosterone secretion, a few cases of spontaneous remission of primary aldosteronism, with normal ranges of blood pressure, plasma potassium, plasma renin activity, and aldosterone renin ratio, have been reported after long-term treatment with MRAs.  相似文献   
110.
    
In recent years, the choice of immune checkpoint inhibitors (ICIs) as a treatment based on high expression of programmed death-ligand 1 (PD-L1) in lung cancers has been increasing in prevalence. The high expression of PD-L1 could be a predictor of ICI efficacy as well as high tumor mutation burden (TMB), which is determined using next-generation sequencing (NGS). However, a great deal of effort is required to perform NGS to determine TMB. The present study focused on γH2AX, a double-strand DNA break marker, and the suspected positive relation between TMB and γH2AX was investigated. We assessed the possibility of γH2AX being an alternative marker of TMB or PD-L1. One hundred formalin-fixed, paraffin-embedded specimens of lung cancer were examined. All of the patients in the study received thoracic surgery, having been diagnosed with lung adenocarcinoma or squamous cell carcinoma. The expressions of γH2AX and PD-L1 (clone: SP142) were evaluated immunohistochemically. Other immunohistochemical indicators, p53 and Ki-67, were also used to estimate the relationships of γH2AX. Positive relationships between γH2AX and PD-L1 were proven, especially in lung adenocarcinoma. Tobacco consumption was associated with higher expression of γH2AX, PD-L1, Ki-67, and p53. In conclusion, the immunoexpression of γH2AX could be a predictor for the adaptation of ICIs as well of as PD-L1 and TMB.  相似文献   
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