A survey of approaches for the visual model-driven development of next generation software-intensive systems

Software-intensive systems of the future are expected to be highly distributed and to exhibit adaptive and anticipatory behavior when operating in highly dynamic environments and interfacing with the physical world. Therefore, visual modeling techniques to address these software-intensive systems require a mix of models from a multitude of disciplines such as software engineering, control engineering, and business process engineering. As in this concert of techniques software provides the most flexible element, the integration of these different views can be expected to happen in the software. The software thus includes complex information processing capabilities as well as hard real-time coordination between distributed technical systems and computers.In this article, we identify a number of general requirements for the visual model-driven specification of next generation software-intensive systems. As business process engineering and software engineering are well integrated areas and in order to keep this survey focused, we restrict our attention here to approaches for the visual model-driven development of adaptable software-intensive systems where the integration of software engineering with control engineering concepts and safety issues are important. In this survey, we identify requirements and use them to classify and characterize a number of approaches that can be employed for the development of the considered class of software-intensive systems.     

SWOF - an open framework for shared workspaces to support different cooperation tasks

Computer supported collaborative work (CSCW) allows people to cooperate by computers from different places and at different times. To enable an easier integration of such collaborative components into web-based communities and portals, a Shared Workspace Open Framework (SWOF) was developed. This framework provides the basic features of shared workspaces and can be customized to different cooperation cases. High usability is an important aspect of the implementation. To achieve these aims SWOF focuses on an information space with more task-suited item-types that can help to pre-structure the information. Thus, on the one hand the system can help the users to write down the needed information in a consistent way and, on the other, could reduce the arguments between the group members on how to structure their workspace. As a use case for SWOF the development of a Web-based portal for the community of man-machine interaction was chosen. In the project MMI-Interaktiv, a portal is built with a SWOF-based shared workspace component. An evaluation for this use case is presented.     

Heat transfer between gas fluidized beds of solid particles and the surfaces of immersed heat exchanger elements,part I

After some general remarks about fluidization, and a section on the hydrodynamic behaviour of fluidized beds, the mechanisms of heat transfer between the surfaces of heat exchanger elements and gas—solid fluidized beds are discussed in detail. A theoretical model, presented some years ago, is slightly modified and further developed to improve its applicability within a wide range of variables. The model makes use of some of the basic concepts of molecular kinetic theory as applied to solid particles in a fluidized bed. A complete derivation as well as all the parameters required to apply the model equations are given.     

Development of novel 1,2,3,4-tetrahydroisoquinoline derivatives and closely related compounds as potent and selective dopamine D3 receptor ligands

Based on N-alkylated 1,2,3,4-tetrahydroisoquinoline derivatives, which are structurally related to the partial agonist BP 897, a series of novel, selective dopamine D3 receptor antagonists has been synthesised. Derivatisation included changes in the arylamide moiety and the tetrahydroisoquinoline substructure leading to compounds with markedly improved selectivities and affinities in the low nanomolar concentration range. From the 55 structures presented here, (E)-3-(4-iodophenyl)-N-(4-(1,2,3,4-tetrahydroisoquinolin-2-yl)butyl)acrylamide (51) has high affinity (Ki(hD3)=12 nM) and a 123-fold preference for the D3 receptor relative to the D2 receptor subtype. Its pharmacological profile offers the prospect of a novel radioligand as a tool for various dopamine D3-receptor-related in vitro and in vivo investigations.     

Diffusion-related implications for langasite resonator operation

Oxygen and gallium diffusivities in langasite were experimentally determined by analysis of diffusion profiles of 18O and 71Ga tracers by SIMS analysis as functions of temperature and doping. Strontium-enhanced diffusivities and activation energies of approximately 1.2+/-0.2 eV confirm the predominant role of oxygen vacancies in controlling the electrical conductivity of langasite at elevated temperature and oxygen partial pressure. The potential impact of high levels of porosity and the use of an oxygen primary ion beam on the accuracy of some of the data is discussed. The gallium diffusivity, with activation energy of 3.13 eV, was found to be more than two orders of magnitude lower than that of oxygen. Surface exchange measurements enabled estimation of gallium loss at elevated temperatures and oxygen partial pressure; the level is not believed to be of major concern for resonator performance.     

Correcting ocular spherical aberration with soft contact lenses

Following aberroscopy, aspheric front surface soft contact lenses (SCLs) were custom-made to correct spherical refractive error and ocular spherical aberration (SA) of 18 myopic and five hypermetropic subjects (age, 20.5 +/- 5 yr). On-eye residual aberrations, logMAR visual acuity, and contrast sensitivity were compared with the best-correcting spectacle lens, an equally powered standard SCL, and an SCL designed to be aberration free in air. Custom-made and spherical SCLs reduced SA (p < 0.001; p < 0.05) but did not change total root-mean-square (rms) wave-front aberration (WFA). Aberration-free SCLs increased SA (p < 0.05), coma (p < 0.05), and total rms WFA. Visual acuity remained unchanged with any of the SCL types compared with the spectacle lens correction. Contrast sensitivity at 6 cycles/degree improved with the custom-made SCLs (p < 0.05). Increased coma with aspheric lens designs and uncorrected astigmatism limit the small possible visual benefit from correcting ocular SA with SCLs.     

COLLATE – A collaboratory supporting research on historic European films

In the COLLATE project, we aim to design and implement a Web-based collaboratory for archives, scientists, and end users working with digitized cultural material. Our example domain is the historic film documentation comprising digitized material about European films of the early 20th century. Designed as a content- and context-based knowledge working environment for distributed user groups, the COLLATE system supports both individual work and collaboration of domain experts who are analyzing, evaluating, indexing, and annotating material in the data repository. The system provides appropriate task-based interfaces for indexing and annotating. As a multifunctional means of in-depth analysis, annotations can be made individually but also collaboratively, for example in the form of annotation of annotations. Combining results from manual and automatic indexing procedures, elaborate content- and context-based information retrieval mechanisms can be applied.