Electrostatic image theory for two anisotropic half-spaces

An image solution for the canonical electrostatic problem of a point charge in an anisotropic half-space bounded by another anisotropic half-space is presented. The image source is obtained in operator form by using Fourier-transformed Maxwell equations and transmission line theory. After applying Heaviside operator calculus the image operator can be interpreted as a combination of a point charge and a sector of planar charge. The new theory is shown to coincide with the previously known image solutions of less general anisotropic media. In addition to being applicable to any physically feasible anisotropic medium of electrostatics, the method can be used for steady-current conductivity problems via a duality transformation.     

Additive manufacturing of monolithic supercapacitors with biopolymer separator

Journal of Applied Electrochemistry - In this paper, additive layer-by-layer fabrication of a fully screen printed monolithic supercapacitor exhibiting performance comparable with supercapacitors...     

A hybrid approach to computing electrostatic forces in fluidized beds of charged particles

In particulate flow devices particles acquire electric charge through triboelectric charging, and resulting electrostatic forces can alter hydrodynamics. To capture this effect, the electrostatic force acting on individual particles in the device should be computed accurately. Electrostatic force is calculated using a hybrid approach consisting of: (1) long‐range contributions from an Eulerian electric field solved using the Poisson equation (2) short‐range contributions calculated using a truncated pairwise sum and (3) a correction to avoid double counting. Euler‐Lagrange simulation of flows incorporating this hybrid approach reveals that bed height oscillations in small fluidized beds of particles with monopolar charge decreases with increasing charge level, which is related to lateral segregation of particles. A ring‐like layer of particles, reported in experimental studies, forms at modestly high charge levels. Beds with equal amounts of positively and negatively charged particles are fluidized in a manner similar to uncharged particles. © 2016 American Institute of Chemical Engineers AIChE J, 62: 2282–2295, 2016     

Surface hydrophobization of CNF films by roll-to-roll HMDSO plasma deposition

Cellulosic films are typically sensitive towards moisture which limits their industrial applicability. In this study the films made from cellulose nanofibrils (CNF) were surface silylated with hexamethyldisiloxane (HMDSO) by roll-to-roll plasma deposition. The effects on surface hydrophobicity were clear and indisputable. Water contact angles of non-modified and plasma-deposited CNF films were 23° and 103°, respectively. As a result of surface silylation the relative polarity decreased from 46.8% to 0.6%. Surface hydrophobicity correlated well with the plasma deposition line speeds (0.5, 5, and 10 m/min) and the water vapor barrier properties. Silylation also decreased the oxygen transmission rates both at 50% and 80% relative humidity as compared to non-modified CNF films. All films were completely impermeable to olive oil and intact in contact with castor oil, toluene, and n-heptane or mixtures of them. The developed surface hydrophobization method can be exploited in strengthening the position of cellulosic films in high performance film applications.     

Introducing Glycolinkers for the Functionalization of Cytotoxic Drugs and Applications in Antibody–Drug Conjugation Chemistry

Antibody–drug conjugates (ADCs) are promising alternatives to naked antibodies for selective drug‐delivery applications and treatment of diseases such as cancer. Construction of ADCs relies upon site‐selective, efficient and mild conjugation technologies. The choice of a chemical linker is especially important, as it affects the overall properties of the ADC. We envisioned that hydrophilic bifunctional chemical linkers based on carbohydrates would be a useful class of derivatization agents for the construction of linker–drug conjugates and ADCs. Herein we describe the synthesis of carbohydrate‐based derivatization agents, glycolinker–drug conjugates featuring the tubulin inhibitor monomethyl auristatin E and an ADC based on an anti‐EGFR antibody. In addition, an initial in vitro cytotoxicity evaluation of the individual components and the ADC is provided against EGFR‐positive cancer cells.     

Identification of novel pyranoanthocyanins in berry juices

In most fruit and berry products the attractive red color is unstable and easily susceptible to degradation. The colors of strawberry and raspberry juices can be enhanced and stabilized by the addition of cinnamic acids. The aim of this study was to identify the novel anthocyanin products responsible for the improved juice color. The pyranoanthocyanins formed were detected using high-performance liquid chromatography, and the fractions from this were analyzed using a nano-ESI tandem MS technique. The pyranoanthocyanins identified were formed from reactions of the main anthocyanins of strawberry and raspberry juices with ferulic acid or sinapic acid. The new anthocyanin derivatives were the 4-vinylguaiacol and 4-vinylsyringol adducts of pelargonidin and cyanidin. This is the first time that pelargonidin 3-glucoside-based vinylphenol pyranoanthocyanins and pyranoanthocyanins with more complex sugar residues have been found. This is also the first time pyranoanthocyanins have been detected in strawberry and raspberry juices.     

Rigorous and approximate analysis of metallic gratings in soft X-ray and EUV regions

Abstract

In deep ultraviolet and soft X-ray regions the complex refractive indices of metals differ substantially from their values in the visible region of the spectrum. The implications of this fact are analysed for metallic gratings illuminated by electromagnetic fields with wavelengths ranging from soft X‐rays to near infrared, concentrating on short wavelengths. In particular, we study metal-stripe gratings (linear polarizers for visible light) by rigorous diffraction theory to determine the short-wavelength region in which a combination of the geometrical thin-element approximation and the theory of single-layer films can be applied. Then we study inductive grid filters for protection of X-ray detectors from infrared radiation in space applications.     

Considerations for Synchronization in Body Area Networks for Human Activity Monitoring

In this paper, we highlight considerations for synchronization issues in body area networks. Requirements for the synchronization accuracy in body area networks depend on the application at hand. Synchronization may be needed for power management, sample ordering, calculation of stimulus responses and for sensor fusion. This paper provides a theoretical exercise to help understand the accuracy required for typical human motion sensing. It gives an overview of various synchronisation strategies used and implemented in prototype systems. Lessons learnt from practical implementations using Bluetooth, an IEEE 802.15.4 proprietary network and Nanonet are presented to illustrate the principles involved. The discussion provides some considerations and the requirements for typical WBAN applications.     

Use of adipose stem cells and polylactide discs for tissue engineering of the temporomandibular joint disc

There is currently no suitable replacement for damaged temporomandibular joint (TMJ) discs after discectomy. In the present study, we fabricated bilayer biodegradable polylactide (PLA) discs comprising a non-woven mat of poly(L/D)lactide (P(L/D)LA) 96/4 and a P(L/DL)LA 70/30 membrane plate. The PLA disc was examined in combination with adipose stem cells (ASCs) for tissue engineering of the fibrocartilaginous TMJ disc in vitro. ASCs were cultured in parallel in control and chondrogenic medium for a maximum of six weeks. Relative expression of the genes, aggrecan, type I collagen and type II collagen present in the TMJ disc extracellular matrix increased in the ASC-seeded PLA discs in the chondrogenic medium. The hypertrophic marker, type X collagen, was moderately induced. Alcian blue staining showed accumulation of sulphated glycosaminoglycans. ASC differentiation in the PLA discs was close to that observed in pellet cultures. Comparison of the mRNA levels revealed that the degree of ASC differentiation was lower than that in TMJ disc-derived cells and tissue. The pellet format supported the phenotype of the TMJ disc-derived cells under chondrogenic conditions and also enhanced their hyalinization potential, which is considered part of the TMJ disc degeneration process. Accordingly, the combination of ASCs and PLA discs has potential for the development of a tissue-engineered TMJ disc replacement.     

Gone with the wind? Newspaper discourse of eutrophication and blue‐green algae blooms in Finland

The mass media shape the public and policy agenda by giving prominence to certain ecosystem changes and risks, as well as by framing some policy measures as the preferred ones. Based on longitudinal analysis of the leading Finnish newspaper, this study considers the media coverage of eutrophication. The results show an increase of reporting in the late 1990s as a result of intertwined ecological and social factors – i.e. intense algal occurrences and establishment of a national communication system. The news coverage has highlighted the harmful algal blooms and health risks of algal toxins and has framed short‐term weather conditions as the key factor regulating algal occurrences. This creates a challenge for environmental management aimed at reduction in the nutrient discharges that influence the state of the environment in the long term.