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111.
George M. Isakander Ibrahim El Shiekh El Khawad Hassan B. Zahran Elmer O. Schlemper 《Advanced Synthesis \u0026amp; Catalysis》1989,331(1):82-88
2-Aroyl-3-methyl-1 H-1,4-benzothiazine ylids ( 2a – k ) were prepared by alkylation of the corresponding 4H-benzothiazines 1 . The ylids 2 are labile at room temperature; proper analytical and 1H-n.m.r. data were obtained for their picrates. E.s.r. studies of u. v. irradiated polycrystalline form of ( 2 ; R1 = Me, R2 = H) gave evidence for a long-lived benzothiazinyl radical with the odd electron residing on nitrogen 6 . 相似文献
112.
113.
Hypocholesterolaemic effect of yoghurt containing Bifidobacterium pseudocatenulatum G4 or Bifidobacterium longum BB536 总被引:4,自引:0,他引:4
The effect of a yoghurt supplement containing Bifidobacterium pseudocatenulatum G4 or Bifidobacterium longum BB536 on plasma lipids, lipid peroxidation and the faecal excretion of bile acids was examined in rats fed a cholesterol-enriched diet. After 8 weeks, the rats in the positive control (PC) group who were fed the cholesterol-enriched diet showed significant increases in plasma total cholesterol (TC), low-density lipoprotein (LDL) cholesterol, and malondialdehyde (MDA). However, groups fed a cholesterol-enriched diet supplemented with yoghurt containing B. pseudocatenulatum G4 or B. longum BB536 had significantly lower plasma TC, LDL-C, very-low-density lipoprotein (VLDL) cholesterol, and MDA than had the PC group after 8 weeks of treatment. In addition, faecal excretion of bile acids was markedly increased in the rats fed the yoghurt containing B. pseudocatenulatum G4 or B. longum BB536 as compared to the PC and NC groups. 相似文献
114.
Michael H. Gordon Ibrahim Abdul Rahman 《Journal of the American Oil Chemists' Society》1991,68(8):574-576
The effect of various processing procedures on the composition and oxidative stability of coconut oil has been studied. The
crude oil is relatively stable but major reductions in oxidative stability occur during the bleaching of oil degummed with
phosphoric acid; during alkali refining; during the deodorization of oil degummed with citric acid and bleached; and during
the deodorization of oil processed with a combined phosphoric acid degumming and bleaching operation. The reasons for the
loss of oxidative stability during processing are discussed with reference to changes in the composition of the oil. Residual
traces of citric acid or phosphoric acid play an important role in stabilizing processed oils. The tocopherol content is also
important, although no additional stabilization of the oil occurs on adding levels of tocopherol above those present naturally
in the crude oil. A combined phosphoric acid degumming and bleaching process leads to smaller losses of tocopherols than sequential
treatments. 相似文献
115.
Fine flour from corn and the isolated starch were dextrinized in the presence of acid and irradiated with y-rays. Starch irradiated with high doses of y-rays was highly modified while fine flour was less affected. The irradiated starch was reduced with sodium borohydride and then hydrolysed. Erythritol and other compounds were identified in the hydrolysate. It was concluded that the C2-C3 bonds in the intermediate glucose units are probably broken by irradiation. Such hypothesis was confirmed by periodate oxidation, hydrolysis with α-amylase and ferricyanide number determination of the irradiated starch. 相似文献
116.
Anna Liguori Alessandro De Vita Giulia Rossi Luisa Stella Dolci Silvia Panzavolta Chiara Gualandi Laura Mercatali Toni Ibrahim Maria Letizia Focarete 《International journal of molecular sciences》2022,23(6)
In the clinical management of solid tumors, the possibility to successfully couple the regeneration of injured tissues with the elimination of residual tumor cells left after surgery could open doors to new therapeutic strategies. In this work, we present a composite hydrogel–electrospun nanofiber scaffold, showing a modular architecture for the delivery of two pharmaceutics with distinct release profiles, that is potentially suitable for local therapy and post-surgical treatment of solid soft tumors. The composite was obtained by coupling gelatin hydrogels to poly(ethylene oxide)/poly(butylene terephthalate) block copolymer nanofibers. Results of the scaffolds’ characterization, together with the analysis of gelatin and drug release kinetics, displayed the possibility to modulate the device architecture to control the release kinetics of the drugs, also providing evidence of their activity. In vitro analyses were also performed using a human epithelioid sarcoma cell line. Furthermore, publicly available expression datasets were interrogated. Confocal imaging showcased the nontoxicity of these devices in vitro. ELISA assays confirmed a modulation of IL-10 inflammation-related cytokine supporting the role of this device in tissue repair. In silico analysis confirmed the role of IL-10 in solid tumors including 262 patients affected by sarcoma as a negative prognostic marker for overall survival. In conclusion, the developed modular composite device may provide a key-enabling technology for the treatment of soft tissue sarcoma. 相似文献
117.
118.
The density of heat transfer rate from a vertical array of flat tubes in cross flow is maximized under fixed pressure drop using constructal design. With the constructal design, the tube arrangement is found such that the heat currents from the tubes to the coolant flow easily. The constraint in the present constructal design is the volume where the tubes are arranged inside it. The two degrees of freedom available inside the volume are the tube‐to‐tube spacing and the length of the flat part of the tubes (tube flatness). The tubes are heated with constant surface temperature. The equations of continuity, momentums, and energy for steady, two‐dimensional, and laminar forced convection are solved by means of a finite‐volume method. The ranges of the present study are Bejan number (dimensionless pressure drop) (103 ≤ Be ≤ 105) and tube flatness (dimensionless length of the tube flat part) (0 ≤ F ≤ 0.8). The coolant used is air with Prandtl number (Pr = 0.72). The results reveal that the maximum heat transfer density decreases when the tube flatness decreases at constant Bejan number. At constant tube flatness, the heat transfer density increases as the dimensionless pressure drop (Bejan number) increases. Also, the optimal tube‐to‐tube spacing is constant, irrespective of the tube flatness at constant Bejan number. 相似文献
119.
Guven Ibrahim Cinar Kenan 《International Journal of Mechanics and Materials in Design》2019,15(4):695-714
International Journal of Mechanics and Materials in Design - A method based on X-ray micro-CT was introduced to create realistic representative volume elements (RVE) for particulate-filled... 相似文献
120.
Blends of Cold Pressed Black Cumin Oil and Sunflower Oil with Improved Stability: A Study Based on Changes in the Levels of Volatiles,Tocopherols and Thymoquinone during Accelerated Oxidation Conditions 下载免费PDF全文