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101.
Administered training to Ss at varying levels of cognitive organization. Ss were 60 middle-class Israeli 6-7 yr olds. The training condition exploited structural mix between operational length and intuitive speed concepts, such that Ss successively alternated partial structures underlying these concepts. Findings were that (a) training was effective for operational speed concept acquisition among Ss with structural mix; (b) training was not effective for Ss without structural mix; (c) those who acquired the operational speed concept also acquired operational reasoning for the concept of movement; and (d) all Ss who employed an integration strategy during training became operational for speed on the posttest, while none who used other strategies acquired operational reasoning for the speed concept. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   
102.
Average rates of polypeptide chain elongation have been determined in cockerel liver explants on 4 successive days following an in vivo injection of 17 beta-estradiol. Incorporation of [3H]leucine by the explants is linear for at least 24 h, and the rate of protein synthesis increases significantly after estrogen injection. The explants synthesize and secrete serum albumin. B-apolipoprotein, and the phosphoprotein vitellogenin at relative rates which are similar to those reported for liver in vivo. Using this system, changes in the average rates of polypeptide chain elongation have been analyzed as a temporal sequence following a single injection of 17 beta-estradiol into cockerels. For this, average ribosome half-transit times were determined by measuring the kinetics of transfer of labeled polypeptides from polysomal-bound to released polypeptides. The data revealed a dramatic effect of estradiol on the average ribosome half-transit time with a maximum increase of 4.6-fold; however, the average size of polypeptides synthesized by explants at the peak of induction increased only 15% when compared to uninduced liver explants. These findings indicate that injection of estradiol results in large changes in the actual rates at which amino acids are added to the growing nascent polypeptide chain; that is, rates of polypeptide chain elongation. Therefore, translation-level regulation of protein synthesis in cockerel livers plays a significant part in determining the magnitude of the response to hormone stimulation.  相似文献   
103.
104.
    
Multispectral photodetectors (MSPs) and circularly polarized light (CPL) sensors are important in opto-electronics, photonics, and imaging. A capacitive photodetector consisting of an interdigitated electrode coated with carbon dot/anthraquinone-polydiacetylene is constructed. Photoexcitation of the carbon dots induces transient electron transfer to the anthraquinone moieties, and concomitant change in the film dielectric constant and recorded capacitance. This unique photodetection mechanism furnishes wavelength selectivity that is solely determined by the absorbance of the carbon dots incorporated in the anthraquinone-polydiacetylene matrix. Accordingly, employing an array of polymerized-anthraquinone photodetector films comprising carbon dots (C-dots) exhibiting different excitation wavelengths yielded optical “capacitive fingerprints” in a broad spectral range (350–650 nm). Furthermore, circular light polarization selectivity is achieved through chiral polymerization of the polydiacetylene framework. The carbon dot/anthraquinone-polydiacetylene capacitive photodetector features rapid photo-response, high fidelity, and recyclability as the redox reactions of anthraquinone are fully reversible. The carbon dot/anthraquinone-polydiacetylene platform is inexpensive, easy to fabricate, and consists of environmentally friendly materials.  相似文献   
105.
    
Peppers are rich in health-promoting phytochemicals, which are involved in the defence mechanisms against cancer. To select a lead variety of pepper with anti-proliferative activity against colon cancer cells and liver cancer cells, high antioxidant activity, and high concentrations of capsaicin, flavonoids and phenolics, we compared these attributes in nine different pepper accessions belonging to Capsicum annuum and C. chinense. Quality parameters such as weight loss and total soluble solids content were tested as well. The different parameters were determined immediately after harvest and after prolonged storage and marketing simulation. A significant variation of these traits was detected among the accessions. C. chinense line 1745 had the highest antioxidant activity, the highest levels of capsaicin and flavonoids, a high and specific anti-cancer activity, and the lowest weight loss level during postharvest storage. It is proposed that line 1745 has potential for use as a source for health-promoting traits and should be further evaluated for use as a nutraceutical for the prevention and treatment of colon and liver cancers.  相似文献   
106.
    
Critical infrastructure and facilities are central assets in modern societies, but their impact on international disaster relief remains mostly associated with logistics challenges. The emerging literature on cascading disasters suggests the need to integrate the nonlinearity of events in the analyses. This article investigates three case studies: the 2002 floods in the Czech Republic, Hurricane Katrina in 2005 and the 2011 Tohoku earthquake, tsunami and Fukushima meltdown in Japan. We explore how the failure of critical infrastructure can orient international disaster relief by shifting its priorities during the response. We argue that critical infrastructure can influence aid request and delivery, changing needs to address the cascades, and contain cascading technology‐based events. The conclusions propose remaining challenges with applying our findings.  相似文献   
107.
    
Evidence is accumulating to consider the gut microbiome as a central player in the gut‐kidney axis. Microbiome products, such as advanced glycation end products, phenols, and indoles, are absorbed into the circulation but are cleared by normal‐functioning kidneys. These products then become toxic and contribute to the uremic load and to the progression of chronic kidney failure. In this review, we discuss the gut‐kidney interaction under the state of chronic kidney failure as well as the potential mechanisms by which a change in the gut flora (termed gut dysbiosis) in chronic kidney disease (CKD) exacerbates uremia and leads to further progression of CKD and inflammation. Finally, the potential therapeutic interventions to target the gut microbiome in CKD are discussed.  相似文献   
108.
We construct a general-purpose multi-input functional encryption scheme in the private-key setting. Namely, we construct a scheme where a functional key corresponding to a function f enables a user holding encryptions of \(x_1, \ldots , x_t\) to compute \(f(x_1, \ldots , x_t)\) but nothing else. This is achieved starting from any general-purpose private-key single-input scheme (without any additional assumptions) and is proven to be adaptively secure for any constant number of inputs t. Moreover, it can be extended to a super-constant number of inputs assuming that the underlying single-input scheme is sub-exponentially secure. Instantiating our construction with existing single-input schemes, we obtain multi-input schemes that are based on a variety of assumptions (such as indistinguishability obfuscation, multilinear maps, learning with errors, and even one-way functions), offering various trade-offs between security assumptions and functionality. Previous and concurrent constructions of multi-input functional encryption schemes either rely on stronger assumptions and provided weaker security guarantees (Goldwasser et al. in Advances in cryptology—EUROCRYPT, 2014; Ananth and Jain in Advances in cryptology—CRYPTO, 2015), or relied on multilinear maps and could be proven secure only in an idealized generic model (Boneh et al. in Advances in cryptology—EUROCRYPT, 2015). In comparison, we present a general transformation that simultaneously relies on weaker assumptions and guarantees stronger security.  相似文献   
109.
Three experiments were conducted to show that engaging in an effort to answer a question markedly influences the processing of information subsequently encountered in the environment. On each of 2 successive days, participants were given a definition test that involved the recall of rare English words cued by their definitions. A lexical-decision task was administered between the 2 definition tests; the timing of the lexical-decision task varied across experiments. A strong target-to-definition priming effect occurred such that prior exposure to words during the lexical-decision task increased their likelihood of being recalled in the final definition test. It also appears that earlier attempts to answer questions affected the acquisition of relevant new material in long-term memory. The role of these priming effects is discussed with respect to the process of updating memory representations. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   
110.
Scent has been well documented as having significant effects on emotion (Alaoui-Ismaili in Physiol Behav 62(4):713–720, 1997; Herz et al. in Motiv Emot 28(4):363–383, 2004), learning (Smith et al. in Percept Mot Skills 74(2):339–343, 1992; Morgan in Percept Mot Skills 83(3)(2):1227–1234, 1996), memory (Herz in Am J Psychol 110(4):489–505, 1997) and task performance (Barker et al. in Percept Mot Skills 97(3)(1):1007–1010, 2003). This paper describes an experiment in which environmentally appropriate scent was presented as an additional sensory modality consistent with other aspects of a virtual environment called DarkCon. Subjects’ game play habits were recorded as an additional factor for analysis. Subjects were randomly assigned to receive scent during the VE, and/or afterward during a task of recall of the environment. It was hypothesized that scent presentation during the VE would significantly improve recall, and that subjects who were presented with scent during the recall task, in addition to experiencing the scented VE, would perform the best on the recall task. Skin-conductance was a significant predictor of recall, over and above experimental groups. Finally, it was hypothesized that subjects’ game play habits would affect both their behavior in and recall of the environment. Results are encouraging to the use of scent in virtual environments, and directions for future research are discussed. The project described herein has been sponsored by the US Army Research, Development, and Engineering Command (RDECOM). Statements and opinions expressed do not necessarily reflect the position or the policy of the US Government; no official endorsement should be inferred.  相似文献   
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