Methods to assess physical activity with special reference tomotion sensors and accelerometers

Motion sensors may be applied for the assessment of physical activity. This paper reviews the evolution of these instruments from the mechanical pedometer to the electronic accelerometer. We conclude that for accurate assessment of physical activity under free living conditions the recently introduced accelerometer looks most promising, although little information was available regarding the reliability of these instruments. Subsequently, reliability of an accelerometer with a three-directional sensor was examined. Intrainstrument variation in a bench test was less than 8% during four measurements over a week. Interinstrument variation during treadmill experiments while subjects wore two accelerometers at the same time was on average 22% and was not improved after adjustment for differences found in the bench test. Reproducibility in the treadmill experiment was approximately 76, 85, and 95% at 3, 5, and 7 km/h, respectively. Bench testing revealed that the sensitivity of a piezoelectric element is prone to shifts, probably due to mechanical, electromagnetic, and/or temperature shock, which may be encountered during outdoor application. However, the relevance of the bench test in this study may be questioned, as results did not correspond with the findings in subjects. This needs further investigation.     

New results in spectral estimation of decimated processes

The aim of this letter is to derive the spectral density of decimated processes, and to establish their model when they are generated from ARMA processes. The optimal conditions of decimation are also discussed.<>     

High-frequency performance of submicrometer channel-length siliconMOSFETs

Polycide-gate silicon n-channel MOSFETs were fabricated on the basis of a standard 0.5-μm MOS technology and measured over the 1.5-26.5-GHz frequency range, in order to investigate the effects of channel-length reduction on device behavior at high frequency. Excellent microwave performances were obtained with a maximum operating frequency (f_max) and a unity-current-gain frequency f _t near 20 GHz for 0.5-μm-gate-length NMOS devices. An equivalent circuit for a MOSFET with its parasitic elements was extracted from measured S-parameter data. The influence of gate resistance, gate-to-drain overlap capacitance, substrate conductivity, and the transit-time effect between the source and drain on microwave characteristics was analyzed     

Asbestos replacement aspects: Modification of the fibre-matrix interphase in lonomer based composites

Asbestos fibres, of the chrysotile variety, and chopped carbon fibres were pretreated by an in-situ polycondensation technique eventually resulting in a polyamide coating on the fibre surface. Ionomer based composites containing either carbon or asbestos fibres in random in plane fibre orientation were prepared, and the influence of this coating process on the tensile properties was investigated. It was found that for the asbestos-filled composites the presence of the nylon 6,6 interlayer improves the tensile performance, especially at moderate polyamide depositions. This is not the case with the pretreated carbon-filled composites for which carbon fibres with higher polyamide contents are preferred. Combinations of the treated asbestos fibres with carbon and/or aramid fibres may be used to reduce the asbestos content in asbestos-only based engineering plastics.     

Measurement of human red blood cell deformability using a single micropore on a thin Si3N4 film

The filtration method for the evaluation of the RBC deformability has been further refined to simulate the deformations encountered in the recticuloendothelial system (in particular the spleen), a recognized site of aged and sickled cells removal. The core of the developed measuring system is a very thin (0.4 micron thick) filter that consists of single micropore (diameters down to 1 micron) on a Si3N4 film which has been constructed using silicon microfabrication techniques. Individual RBC's deformability is quantified measuring the cell pore passage time. From one blood sample 200 passage times are analyzed by a computer, displaying mean and median values as deformability indexes, and class and cumulative histograms for studying the passage times distribution. In this paper the effectiveness of the developed system as a routine clinical evaluation tool is demonstrated by studying several factors that are known to affect the RBC deformability, such as temperature, addition of diamide and glutaraldehyde, and blood storage conditions. In addition, it is experimentally demonstrated that the human RBC can traverse a pore with a diameter as small as 1 micron when the pore length is very short, thus broadening the experimental conditions under which the RBC deformability (fluidity) can be studied.     

A deterministic particle method for the kinetic model of semiconductors: The homogeneous field model

We present a new particle method for the simulation of the semiconductor Boltzmann equation—the weighted particle method. This method differs from the Monte-Carlo method by the approximation of the collision operator—we allocate each particle a weight which varies in time according to the collision integral. This integral is evaluated by means of a quadrature formula, which does not require the use of random numbers. The aim of this paper is to show that this method gives accurate results on physically relevant problems. Linear as well as non-linear collision integrals can be handled the same way by this method. Precise representations of the distribution functions are available, which allow a good insight into the physical processes. In this paper, we only consider the homogeneous field model with an emphasis on the collision operator. Numerical results are presented with a comparison with the Monte-Carlo method.     

The effect of different protein diets on longevity and various biochemical parameters of aged rats]

In this work 23 month old rats were fed for 200 days with different protein diets (NT-diet: 19% protein, 72% of animal origin and LP-diet: 8.8% protein exclusively of vegetable origin). Some metabolic parameters and lifespan (on the base of a 50% death-rate) were determined. The relations of the liver free amino acids glycine + alanine and tyrosine + phenylalanine + branched chain amino acids and the ratio of phenylalanine/tyrosine were determined to be higher in the LP-group. Phenylalanine in liver and urea concentrations in liver and serum were lower in the LP-group. Furthermore the dopamine or serotonin levels were significantly lower in lateral and medial or lateral regions of the hypothalamus respectively in LP-diet fed rats. The norepinephrine content was not modified by the diets. The median lifespan of 23 month old rats was higher by 24% following LP-treatment. These results suggest that the protein component (amino acids) of different diets may modify metabolic parameters and lifespan of animals by mechanisms in which the central regulation may be involved.     

Cimaterol and clenbuterol residue analysis by HPLC-HPTLC in liver.

A method has been developed for the analysis of cimaterol and clenbuterol residues in liver, with detection limits of 0.25 micrograms/kg and 0.5 micrograms/kg, respectively. The recovery varied from 55% to 60%. After extraction, a clean-up procedure with Baker-spe C-18 columns was performed. The two chemical compounds of interest were eluted with methanol. Cimaterol and clenbuterol were quantitatively determined by high-performance liquid chromatography (HPLC) using an RP-Select B (5 microns) column and a post-column reaction procedure. The positive results were confirmed by high-performance thin-layer chromatography (HPTLC) as this technique reaches the same level of sensitivity as the HPLC method.     

Ultrafast all-optical switching in GaAlAs integrated interferometer in 1.55 mu m spectral region

The first observation is reported of ultrafast all-optical switching in an integrated asymmetric Mach-Zehnder interferometer, using the nonresonant nonlinearity in Ga/sub 0.82/Al/sub 0.18/As below half the bandgap. A relative switching fraction of more than 80% has been achieved using 330 fs pulses at around 1.55 mu m from a coupled-cavity mode-locked colour centre laser.<>