Responses of ligamentous fibroblasts to mechanical stimulation

Mechanical stimulation, as provided by physiotherapy or controlled motion is essentially the only factor able to improve anterior cruciate ligament (ACL) healing. We investigate the cellular effects of such stimulus. Two types of stimulations are applied on canine ACL fibroblasts: repetitive stretch of an elastomeric adhesion substrate and a laminar flow of culture media over the culture surface. Cell orientation, proliferation rate, synthesis and type of collagen as well as proteoglycans (PG) synthesis and hydrodynamic characteristics have been studied. According to our results, the fibroblasts tend to align perpendicularly to the deformation axis of their substrate, and along a laminar flow. The shear stress induced by the laminar flow does not modify significantly proliferation rate nor extracellular matrix synthesis. Substrate stretching however, increases proliferation rate, collagen synthesis, mostly type III, and PG synthesis, principally of small sizes. The characteristics of fibroblasts submitted to repeated deformation match those of fibroblasts from ligament scar tissues. Their orientation perpendicular to substratum deformation differs from the one usually encountered in the undamaged tissue: aligned on the ligament axis.     

The topographic normalization of hyperspectral data: implications for the selection of spectral end members and lithologic mapping

Compact Airborne Spectrographic Imager (CASI) hyperspectral data is used to investigate the effects of topography on the selection of spectral end members, and to assess whether the topographic correction improves the discrimination of rock units for lithologic mapping. A publicly available Digital Elevation Model (DEM), at a scale of 1:50,000, is used to model the radiance variation of the scene as a function of topography, assuming a Lambertian surface. Skylight is estimated and removed from the airborne data using a dark object correction. The CASI data is corrected on a pixel-by-pixel basis to normalize the scene to a uniform solar illumination and viewing geometry. The results show that topography has the effect of expanding end member clusters at times resulting in the overlap of clusters and that the correction process can effectively reduce the variation in detected radiance due to changes in local illumination. When topographic effects are embedded in the hyperspectral data, methods typically used for the selection of end members, such as the convex hull method, can miss end members or result in the selection of nonrepresentative pixels as end members. Thus, end members selected by some conventional methods are very likely “incomplete” or “nonrepresentative” if the topographic effect is embedded in the data. As shown in this study, the topographic correction can reveal hidden end members and achieve a better representation of end members via the statistical center of isolated clusters.     

一个实用程控交换机系统及可靠性设计

程控交换机是通信网的关键部分，其可靠性直接影响通信的安全性与有效性。本文对程控交换机实用产品的可靠性设计措施，如主控板双机备份、数据传输校验及程序复执等进行了论述，并提出了一些实用的具体方法。对用后台处理机进行话务信息处理作了基本介绍。     

350MW机组锅炉引风机出力不足原因分析及解决措施

针对某电厂350 MW机组锅炉引风机出力不足、带负荷能力低的问题,通过现场测试与计算,分析引风机出力不足、机组不能高负荷运行的原因,判断其主要受煤质变化、烟道漏风大、烟道阻力上升等因素影响,导致引风机出力不足,并提出整改措施.     

Internal deterioration of concrete by the oxidation of pyrrhotitic aggregates

This paper presents research results on the causes of a severe concrete deterioration, which occurred in many building foundations approximately 2 years after construction. Concrete samples were investigated with X-ray diffraction (XRD) analysis, a scanning electron microscope (SEM) and a petrographic examination performed with a stereomicroscope. It was found that the early cracking of concrete stemmed from the oxidation of the pyrrhotite found in the anorthosite aggregates used to produce the concrete. The oxidation process led to the precipitation of iron hydroxides having a higher volume than the original pyrrhotite does. The presence of micas (biotite) close to the pyrrhotite seemed to promote and accelerate the oxidation process.     

双十字轴对称式结构压磁式力传感器设计与研究

该研究针对拖拉机电液提升设备所用的压磁式力传感器进行了分析,设计了一种双十字轴对称式力传感器.改进传感器励磁磁芯结构并增加励磁磁芯的数量,增大了磁场偏置程度,实现了同时检测两个方向上的作用力,也实现了同时检测多个剪切面上的作用力,更加符合拖拉机电液提升设备的实际使用状况,提高了传感器灵敏度.建立了传感器磁路数学模型,并根据数学模型在MATLAB/Simulink中建立仿真模型,通过仿真和实验对传感器静态性能进行分析,验证了该传感器不存在因自身结构改进而产生零点漂移现象,得到了不同作用力下的传感器输出特性,验证了传感器磁路数学模型推导的正确性,显示出该传感器具有较高的灵敏度,能更好的适用于拖拉机电液提升设备.     

PXI总线下信号同步的探讨与实现

对PXI总线下实现高速数据采集以及信号同步进行了探讨和研究，并对PXI总线下星形触发作了阐述，利用PXI总线的时钟同步功能和信号的特殊性提出了解决问题的方法。通过PXI总线高速采集系统的实现，得到了多板卡星形触发方式下时钟的不绝对同步结论。     

A process explanation of the effects of institutional distance between parties in outsourced information systems development projects

Outsourced information systems development (OISD) projects are challenging endeavors, and the literature suggests differences between the parties involved as critical hinderers of such projects. Using institutional theory as a foundational theory, we propose a process explanation of the effects of differences between parties in OISD projects. Our explanation relies on the interaction of four components: (1) the IS development and project management institutional profiles of the parties involved; (2) the institutional distance between practices within these profiles; (3) instances of conflicting institutional demands when institutional distance becomes salient; and (4) the repertoire of institutional strategic responses available to parties to address those instances. We suggest that the constitutive elements of institutional distance and the degree to which parties envision their collaboration beyond the project at hand contribute to explaining the enactment of strategic responses. Accounting for the fact that practices, as well as the institutional logics that drive their enactment, may differ between parties, we make a theoretical contribution to the literature on OISD by building a fine-grained explanation of the effects of differences between parties in OISD projects.     

合肥市即食肉类食品中金黄色葡萄球菌污染情况及耐药和基因型分布

目的调查合肥市即食肉类食品中金黄色葡萄球菌的污染情况,并对分离株进行耐药性分析及多位点序列分型研究。方法 2017年10月—2018年10月自合肥市区范围内的超市和开放型菜市场共采集744份即食型肉类食品样品。根据GB 4789.10—2016《食品安全国家标准食品微生物学检验金黄色葡萄球菌检验》中的方法对样品进行金黄色葡萄球菌定性和定量分析,采用K-B纸片扩散法检测分离株的耐药性,采用多位点序列分型法对分离株进行ST分型,使用MEGA 7.0绘制聚类树状图。结果样品中金黄色葡萄球菌检出率为4.2%(31/744),其中卤肉制品检出率最高为8.1%(15/185),其次为烤肉制品(6.3%,11/174),定量分析显示超过90%的样品金黄色葡萄球菌污染水平在0.3～10 MPN/g范围内。耐药性分析结果显示80.6%(25/31)的菌株对青霉素G耐药,40%以上的菌株对链霉素、红霉素和卡那霉素耐药;多重耐药菌株占比为61.3%(19/31)。分型分析共获得8个ST型,分别为ST6、ST7、ST15、ST59、ST72、ST188、ST398和ST2196型,其中以ST188和ST72型为主。结论合肥市卤肉和烤肉制品中存在金黄色葡萄球菌污染,且多重耐药菌株比例较高,对消费者的健康有潜在威胁,有必要持续监测污染率、菌株耐药和基因型流行趋势,完善合肥市食源性金黄色葡萄球菌感染的风险评估。