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The rat's willingness to ingest glucose after an initial intraoral intake test was probed by beginning a 2nd intraoral intake test at variable durations (1–220 min). In Exp 1, after an initial meal of 12.5% glucose solution averaging 26.9?±?1.7 ml, the size of the 2nd (probe) meal of the same stimulus increased linearly from 4.0?±?0.9 ml after a 1-min delay to 15.4?±?2.7 ml after a 120-min delay. In Exp 2, intraoral intake of a more concentrated (37.5%) glucose solution rose more slowly as a function of delay from 2.4?±?2.7 ml to 4.9?±?0.6 ml. For each glucose concentration, the linear recovery function and a slope that depends on stimulus concentration are consistent with a role for gastric emptying during the delay in intake recovery. In Exp 3, rats ingested 12.5% or 37.5% glucose to satiety in an initial test and received, after a variable delay, either the same or the other concentration as the probe stimulus. The same volumes were ingested at each delay whether the glucose concentration of the probe stimulus was the same or was switched from that presented in the initial test. This result shows that the taste and caloric properties of the probe stimulus played no role in determining how much of it would be ingested… (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
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Jones Enrico E.; Ghannam Jess; Nigg Joel T.; Dyer Jennifer F. 《Canadian Metallurgical Quarterly》1993,61(3):381
Articulates a paradigm for single-case research in psychotherapy. A patient diagnosed as having major depressive disorder was seen in an intensive, twice-weekly psychodynamic psychotherapy for 2.5 years. Each session was videotaped, and assessments of patient change were obtained at regular intervals. A time-series analysis was used to model fluctuations in the therapy process to take into account time and the effect of previous events on subsequent changes, thereby preserving the context-determined meaning for therapist and patient actions. A bidirectional analysis of causal effects shows that the influence processes between therapist and patient are mutual and reciprocal and suggests that the effect of the patient on the therapist and on the process has not been made sufficiently explicit in previous models of process and change. The potential of intensive single-case designs for uncovering causal effects in psychotherapy is demonstrated. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
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Chun-Ren Chen Joel L. Zatz Eugene Reilly 《Drug development and industrial pharmacy》1993,19(11):1265-1282
This potential for ion-pairing between dyclonine, a local anesthetic, and pharmaceutical dyes commonly used in liquid pharmaceutical formulations was examined. Occurrence of ion-pairing at a pH of 3 was confirmed by shift of the absorption maximum of all five sulfonate-containing dyes, and by measurements of octanol/water partition coefficient and surface tension. There was also an increase in the uptake of dyclonine by phosphatidylcholine liposomes in the presence of a dye (tartrazine) at pH 3 but not at pH 7, where the uncharged anesthetic is dominant. 相似文献
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According to D. E. Broadbent's (1958) selective filter theory, people do not process unattended stimuli beyond the analysis of basic physical properties. This theory was later rejected on the basis of numerous findings that people identify irrelevant (and supposedly unattended) stimuli. A careful review of this evidence, however, reveals strong reasons to doubt that these irrelevant stimuli were in fact unattended. This review exposed a clear need for new experiments with tight control over the locus of attention. The authors present 5 such experiments using a priming paradigm. When steps were taken to ensure that irrelevant stimuli were not attended, these stimuli produced no priming effects. Hence, the authors found no evidence that unattended stimuli can be identified. The results support a modern version of Broadbent's selective theory, updated to reflect recent research advances. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
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Predd Joel Pfleeger Shari Lawrence Hunker Jeffrey Bulford Carla 《Security & Privacy, IEEE》2008,6(4):66-70
This column goes beyond previous insider analyses to identify a framework for a taxonomy of insider threats including both malicious and inadvertent actions by insiders that put organizations or their resources at some risk. The framework includes factors reflecting the organization, the individual, the information technology system, and the environment. 相似文献
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Explored whether males' satisfaction with an exchange relationship is more dependent on the equity of that relationship, relative to females'. 26 male and 25 female members of 1 of 3 business lead and referral clubs (1 all female, 1 primarily male, and 1 approximately equal in males and females) rated their own and others' inputs and outcomes into the exchange relationship, as well as their satisfaction with the relationship. Results indicate that satisfaction was lower in a negatively inequitable than equitable relationship and slightly lower in an equitable than positively inequitable relationship. As predicted, the relationship of equity and satisfaction was considerably more pronounced for male than female club members. Further analyses revealed that the equity-satisfaction relationship was especially (a) pronounced for males in the primarily male group and (b) weak for females in an all-female group. The latter findings suggest that the salience of the equity norm may be a joint function of the sex of both members of an exchange relationship. (13 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献