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71.
D. P. Recio R. M. Natal Jorge L. M. S. Dinis 《International journal for numerical methods in engineering》2006,68(13):1329-1357
The meshless methods, namely the element‐free Galerkin method (EFGM), when they first appeared claimed that volumetric locking and hourglass were avoided. This was not the case and both phenomena occur in the EFGM. In the context of the finite element method (FEM) these phenomena were widely studied. In this work, forms of avoiding the locking phenomenon will be presented; a formulation based on the enhanced strain method will be introduced in the EFGM and the B‐bar method will be implemented under the scope of the EFGM. Secondly, to render this method more robust, a stabilization technique will be implemented avoiding hourglass. Several examples are solved to probe the efficiency of these techniques. Copyright © 2006 John Wiley & Sons, Ltd. 相似文献
72.
Jongchul Song Walter R. Fagerlund Carl T. Haas Clyde B. Tatum Jorge A. Vanegas 《Canadian Metallurgical Quarterly》2005,131(6):723-733
Prefabrication, preassembly, modularization, and off-site fabrication, collectively termed as prework have become more viable with recent advances in design and information technologies. These construction methods offer a substantial opportunity to improve project performance when circumstances merit. Successful implementation of these methods on a particular project requires systematic analysis and early decision making based on specific factors of the project. This paper identifies those factors influencing decisions on the use of prework, and current industry practices for evaluating the applicability of prework on industrial projects. It then presents a decision framework to assist industry practitioners with evaluating the applicability of prework on their project, and describes a computerized tool to aid project teams in the decision-making process. The developed framework and tool are useful and effective in the decision-making process, and easy to use, as validated by practitioners in the industry. 相似文献
73.
Tuyet Le-Anh Jorge Villalobos Jacky Estublier 《Electronic Notes in Theoretical Computer Science》2003,82(5):164
Reusability is the holly grail of software engineers. But reusability requires powerful composition mechanisms since the pieces to compose have no reason to match perfectly. Unfortunately, the composition mechanisms available today, mostly method call and component assembly are rather primitive. This paper shows what is the current state of the art in software composition, showing that there is little composition flexibility at code level, even using workflow approaches.The approach presented here claims that composition requires reasoning at different levels of abstraction. Workflow support is first decoupled from real tools, using abstract tool modeling. Contracts have been included to increase the independence between process and tools. Then, we have introduced conceptual abstractions linked by contract to real tools. Finally, we show that it is possible to define composition at the abstract level.The resulting system shows very high adaptability capabilities. Experience shows, however, that to be practical, this approach requires adapted framework and specialized tools. This paper shows the experience gained in implementing many versions of such a framework. The current system is currently in industrial use. 相似文献
74.
Gilles Celeux Author Vitae Author Vitae Jorge Marques Author Vitae 《Pattern recognition》2004,37(9):1841-1853
Many recent tracking algorithms rely on model learning methods. A promising approach consists of modeling the object motion with switching autoregressive models. This article is involved with parametric switching dynamical models governed by an hidden Markov Chain. The maximum likelihood estimation of the parameters of those models is described. The formulas of the EM algorithm are detailed. Moreover, the problem of choosing a good and parsimonious model with BIC criterion is considered. Emphasis is put on choosing a reasonable number of hidden states. Numerical experiments on both simulated and real data sets highlight the ability of this approach to describe properly object motions with sudden changes. The two applications on real data concern object and heart tracking. 相似文献
75.
Development of an Active Thermoplastic Film with Oxygen Scavengers Made of Activated Carbon and Sodium Erythorbate 下载免费PDF全文
Ronald Joven Angela Garcia Andrea Arias Jorge Medina 《Packaging Technology and Science》2015,28(2):113-121
An active thermoplastic film made of low‐density polyethylene (LDPE) filled with oxygen scavengers made of powdered activated carbon (PAC) impregnated with sodium erythorbate (SE) was developed for packaging applications. Initial tests indicated that the impregnation of PAC with SE enhanced the heat resistance of SE, thereby allowing processing at temperatures typical of LDPE manufacturing. Subsequently, LDPE films with PAC/SE particles were manufactured in coupons that represented a typical juice package, and experiments indicated that these films absorbed 3.57 mg of oxygen in 11 days. This amount corresponded to 80% the concentration of oxygen in the headspace of the package. Furthermore, findings indicated that active particles alone have 10 times higher oxygen absorption capacity than the active LDPE film. Finally, the physical properties of the film were characterized by microscopy where oxygen scavengers showed a good dispersion within the matrix. However, 20 wt.% of these active particles decreased tensile strength of the film by 53%. Copyright © 2014 John Wiley & Sons, Ltd. 相似文献
76.
Camila Reyes Estefanía Nova-Lamperti Daniel Duran-Sandoval Daniela Rojas Jorge Gajardo Enrique Guzman-Gutierrez Camila Bustos-Ruiz Valeska Ormazbal Felipe A. Zúiga Carlos Escudero Claudio Aguayo 《International journal of molecular sciences》2022,23(13)
Oxidized low-density lipoprotein (ox-LDL) is the most harmful form of cholesterol associated with vascular atherosclerosis and hepatic injury, mainly due to inflammatory cell infiltration and subsequent severe tissue injury. Lox-1 is the central ox-LDL receptor expressed in endothelial and immune cells, its activation regulating inflammatory cytokines and chemotactic factor secretion. Recently, a Lox-1 truncated protein isoform lacking the ox-LDL binding domain named LOXIN has been described. We have previously shown that LOXIN overexpression blocked Lox-1-mediated ox-LDL internalization in human endothelial progenitor cells in vitro. However, the functional role of LOXIN in targeting inflammation or tissue injury in vivo remains unknown. In this study, we investigate whether LOXIN modulated the expression of Lox-1 and reduced the inflammatory response in a high-fat-diet mice model. Results indicate that human LOXIN blocks Lox-1 mediated uptake of ox-LDL in H4-II-E-C3 cells. Furthermore, in vivo experiments showed that overexpression of LOXIN reduced both fatty streak lesions in the aorta and inflammation and fibrosis in the liver. These findings were associated with the down-regulation of Lox-1 in endothelial cells. Then, LOXIN prevents hepatic and aortic tissue damage in vivo associated with reduced Lox-1 expression in endothelial cells. We encourage future research to understand better the underlying molecular mechanisms and potential therapeutic use of LOXIN. 相似文献
77.
The development and computational implementation, on a multibody dynamics environment, of a constitutive relation to model
bushing elements associated with mechanical joints used in the models of road and rail vehicles is presented here. These elements
are used to eliminate vibrations in vehicles, due to road irregularities, to allow small misalignment of axes, to reduce noise
from the transmission, or to decrease wear of the mechanical joints. Bushings are made of a special rubber, used generally
in energy dissipation, which presents a nonlinear viscoelastic relationship between the forces and moments and their corresponding
displacements and rotations. In the methodology proposed here a finite element model of the bushing is developed in the framework
of the finite element code ABAQUS to obtain the constitutive relations of displacement/rotation versus force/moment for different
loading cases. The bushing is modeled in a multibody code as a nonlinear restrain that relates the relative displacements
between the bodies connected with the joint reaction forces, and it is represented by a matrix constitutive relation. The
basic ingredients of the multibody model are the same vectors and points relations used to define kinematic constraints in
any multibody formulation. One particular, and relevant, characteristic of the formulation now presented is its ability to
represent standard kinematic joints, clearance, and bushing joints just by defining appropriate constitutive relations. Spherical,
revolution, cylindrical, and translational bushing joints are modeled, implemented, and demonstrated through the simulation
of two multibody models of a road vehicle, one with perfect kinematic joints for the suspension sub-systems, and other with
bushing joints. The tests conducted include an obstacle avoidance maneuver and a vehicle riding over bumps. It is shown that
the bushing models for vehicle multibody models proposed here are accurate and computationally efficient so that they can
be included in the vehicle models leading reliable simulations. 相似文献
78.
Jorge Lopez-Tello Maria Angeles Jimenez-Martinez Esteban Salazar-Petres Ritik Patel Amy L. George Richard G. Kay Amanda N. Sferruzzi-Perri 《International journal of molecular sciences》2022,23(11)
Pregnancy is characterized by adaptations in the function of several maternal body systems that ensure the development of the fetus whilst maintaining health of the mother. The renal system is responsible for water and electrolyte balance, as well as waste removal. Thus, it is imperative that structural and functional changes occur in the kidney during pregnancy. However, our knowledge of the precise morphological and molecular mechanisms occurring in the kidney during pregnancy is still very limited. Here, we investigated the changes occurring in the mouse kidney during pregnancy by performing an integrated analysis involving histology, gene and protein expression assays, mass spectrometry profiling and bioinformatics. Data from non-pregnant and pregnant mice were used to identify critical signalling pathways mediating changes in the maternal kidneys. We observed an expansion of renal medulla due to proliferation and infiltration of interstitial cellular constituents, as well as alterations in the activity of key cellular signalling pathways (e.g., AKT, AMPK and MAPKs) and genes involved in cell growth/metabolism (e.g., Cdc6, Foxm1 and Rb1) in the kidneys during pregnancy. We also generated plasma and urine proteomic profiles, identifying unique proteins in pregnancy. These proteins could be used to monitor and study potential mechanisms of renal adaptations during pregnancy and disease. 相似文献
79.
María Irene Cerezo-Corts Juan Germn Rodríguez-Castillo Dulce Adriana Mata-Espinosa Estela Isabel Bini Jorge Barrios-Payan Zyanya Lucia Zatarain-Barrn Juan Manuel Anzola Fernanda Cornejo-Granados Adrian Ochoa-Leyva Patricia Del Portillo Martha Isabel Murcia Rogelio Hernndez-Pando 《International journal of molecular sciences》2022,23(9)
80.
Optimization of the material flow in a manufacturing plant by use of artificial bee colony algorithm
Alejandro Alvarado-Iniesta Jorge L. Garcia-Alcaraz Manuel Ivan Rodriguez-Borbon Aide Maldonado 《Expert systems with applications》2013,40(12):4785-4790
To survive in today’s competitive global market, companies must perform strategic changes in order to increase productivity, eliminating wasted materials, time, and effort. This study will examine how to optimize the time and effort required to supply raw material to different production lines in a manufacturing plant in Juarez, Mexico by minimizing the distance an operator must travel to distribute material from a warehouse to a set of different production lines with corresponding demand. The core focus of this study is similar to that of the Vehicle Routing Problem in that it is treated as a combinatorial optimization problem. The artificial bee colony algorithm is applied in order to find the optimal distribution of material with the aim of establishing a standard time for this duty by examining how this is applied in a local manufacturing plant. Results show that using this approach may be convenient to set standard times in the selected company. 相似文献