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11.
Hughes Rosemary B.; Nosek Margaret A.; Howland Carol A.; Groff Janet Y.; Mullen Patricia Dolan 《Canadian Metallurgical Quarterly》2003,48(3):182
Objective: To pilot test a health promotion intervention for women with physical disabilities. Design: Pre- and postintervention questionnaires. Participants: Two groups of women with physical disabilities (n=15). Intervention: Seven-session weekly workshop intervention grounded primarily in social-cognitive theory. Setting: Disability and rehabilitation settings. Main Outcome Measures: Indicators of health status. Results: Statistically significant positive changes between pre- and postintervention scores on measures of self-efficacy for dietary behaviors, medical decision making, social interaction, physical functioning, impact of physical limitation on role activities, and vitality. Conclusion: Women with disabilities who participate in this health promotion intervention may exhibit improvements on indicators of health status. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
12.
Switched-current (SI) signal processing circuits with video frequency performance are presented. The delay cells employ negative feedback to produce a `virtual earth' at the input node to improve transmission accuracy. Fully differential structures with common-mode feedback are used to reduce charge injection errors and crosstalk from digital signals. An IC test circuit, in a 1 μm standard digital CMOS process, containing simple delay lines and an FIR filter section is described, and measured performance is given. Typically, a 2T delay line sampling at 13.3 MHz gave a low-frequency gain error of -54 dB, a settling error of -60 dB, a third-harmonic distortion of -40 dB with 75% modulation, and an S /N ratio of 60 dB. Scaling of the memory cell device dimensions and currents should permit SI operation at clock frequencies beyond 100 MHz 相似文献
13.
The techniques of Feulgen staining, acridine orange staining, and a sperm chromatin structure assay using acridine orange and flow cytometry were compared for selective examination of bovine sperm nuclei. Twenty frozen semen samples were simultaneously analysed by all three methods. The prevalence of abnormally condensed DNA and its relationship to other semen traits were determined in ejaculates from 70 bulbs presented for routine examination for breeding soundness and in frozen semen from 348 bulls evaluated over five years. A breeding trial with 118 beef heifers using semen from six bulls with different degrees of nuclear abnormalities was performed to assess the importance of the defects with respect to fertility. The results indicate that few spermatozoa with abnormal DNA condensation are found in normal semen, but the incidence increases with disturbance of spermatogenesis. However, high numbers of abnormally condensed nuclei were found in the absence of an increase in other defects. This nuclear defect might be at least partially of epididymal origin; it can lower fertility and can be compensated for by increasing the numbers of normal spermatozoa in the insemination dose. The percentage of abnormally condensed sperm nuclei as detected by Feulgen staining was significantly correlated with that detected by microscopy after acridine orange staining and by the sperm chromatin structure assay. We therefore consider the Feulgen technique to be a valuable tool for assessing the nuclear integrity of bovine spermatozoa. 相似文献
14.
Zaleski A. Sinha S.P. Ioannou D.E. Campisi G.J. Hughes H.L. 《Electron Devices, IEEE Transactions on》1995,42(9):1697-1700
By operating one channel of a typical SOI MOSFET in avalanche while keeping the opposite channel accumulated, charge injection into the opposite gate takes place. Three independent experiments are described that demonstrate the occurrence of this opposite-channel based charge injection. The experimental results are in agreement with PISCES numerical simulations 相似文献
15.
16.
Questions several assumptions about the rationale for pharmacological therapies for smoking cessation, including whether (1) future smokers will be those more dependent on nicotine and thus in greater need of nicotine replacement or other pharmacotherapy, (2) transdermal nicotine and nicotine gum work by reducing withdrawal symptoms, and (3) clonidine works by decreasing sympathetic arousal. After describing currently available pharmacotherapies, the article also describes several unexpected findings that need to be taken into consideration by clinicians: (1) Transdermal nicotine is effective when given without psychological therapy, (2) transdermal nicotine and nicotine gum do not consistently decrease postcessation weight gain, (3) high level of nicotine dependence does not consistently predict better response to transdermal nicotine, and (4) clonidine is effective in women but not in men. The article poses other questions for future research. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
17.
JJ Rankine DG Fortune CE Hutchinson DG Hughes CJ Main 《Canadian Metallurgical Quarterly》1998,23(15):1668-1676
STUDY DESIGN: Prospective comparative study of pain drawings with findings on lumbar spine magnetic resonance imaging. OBJECTIVES: To assess the ability of the pain drawing to predict the presence of nerve root compression. SUMMARY OF BACKGROUND DATA: Most research work has concentrated on the ability of the pain drawing to act as a screening method for psychological distress with less work directed at the influence the anatomic abnormality has on the pain drawing. METHODS: One hundred thirty-four consecutive outpatients attending for lumbar magnetic resonance imaging in the investigation of back and leg pain completed pain drawings and psychological testing immediately before the examination. The pain drawing was analyzed by previously reported criteria, and the magnetic resonance imaging was assessed independently for the presence of nerve compression by three radiologists. Multivariate stepwise discriminant analysis was used to identify patients with nerve compression on the basis of their pain drawing. RESULTS: Nerve compression was predicted by numbness in the anterolateral aspect of the foot. There was considerable overlap in the appearances of the pain drawings between patients with and without nerve compression, and the pain drawing correctly classified only 58% of patients with nerve compression. CONCLUSIONS: The pain drawing is not a good predictor of nerve compression on magnetic resonance imaging in a group of patients investigated for back and leg pain. It should be interpreted with caution and in light of the full clinical picture. 相似文献
18.
A truncated form of SAG1, the immunodominant surface antigen of Toxoplasma gondii, has been produced in the methylotrophic yeast, Pichia pastoris. By construction, the recombinant protein lacks C-terminal residues 308-336 which, in native SAG1, encompass the glycosylphosphatidylinositol anchorage site. Secretion of anchor-less SAG1 proceeded via the yeast prepro alpha-mating factor signal peptide and yielded two immunoreactive protein species having apparent molecular masses of 31.5 and 34.5 kDa, respectively, and differing only by N-glycosylation of the single Asn-X-Ser site present in the molecule. Purification of the anchor-less SAG1 was achieved by a combination of ion-exchange and size-exclusion chromatographies. N-terminal amino acid sequencing of the products indicated the presence of additional residues glutamic acid--alanine at the N-terminal end of the products. Despite incomplete processing and unnatural glycosylation, anchor-less SAG1 proteins apparently adopted a suitable conformation recognized by monoclonal and human serum-derived antibodies, specific for the native SAG1. In addition, the recombinant anchor-less SAG1 proved competent for inducing proliferation, in vitro, of mononuclear cells from seropositive individuals. Finally, properly adjuvanted anchor-less SAG1 was able to induce protection of mice against a lethal challenge with T. gondii tachyzoites. 相似文献
19.
This study investigates within-subject variations and associations of salivary viscosities and flow rates in a test panel of healthy adults. After several practice sessions, unstimulated and stimulated whole saliva samples were collected 5 times daily (at 0800, 1100, 1400, 1700, and 2000 h) from 30 university students. There was a significant within-subject variation in viscosity and flow rate of unstimulated saliva (P<0.001). Intra-item correlations were significantly different for salivary flow rates (r= 0.82 for unstimulated, r= 0.88 for stimulated, P< 0.001) and viscosity of unstimulated saliva (r= 0.54, P< 0.05), but viscosity of stimulated saliva was different in this respect. Our results indicate that there is a significant within-subject variation in viscosity of unstimulated saliva. 相似文献
20.
Condia Josie E. Rodriguez Narducci Pierpaolo Sonza Reorda Matteo Sterpone Luca 《The Journal of supercomputing》2021,77(10):11625-11642
The Journal of Supercomputing - General-purpose graphics processing units (GPGPUs) are extensively used in high-performance computing. However, it is well known that these devices’... 相似文献