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91.
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93.
Tomoyuki Kawase Kazuhiro Okuda Hiroyuki Kogami Hitoshi Nakayama Masaki Nagata Hiromasa Yoshie 《Journal of materials science. Materials in medicine》2010,21(2):731-739
Our animal implantation studies have demonstrated that, after osteogenic processing, cultured human periosteal sheets form
osteoid tissue ectopically without the aid of conventional scaffolding materials. To improve the osteogenic activity of these
periosteal sheets, we have tested the effects of including a scaffold made of salmon collagen-coated ePTFE mesh. Periosteal
sheets were produced with minimal manipulation without enzymatic digestion. Outgrown cells penetrated into the coated mesh
fiber networks to form complex multicellular layers and increased expression of alkaline phosphatase activity in response
to the osteoinduction. In vitro mineralization was notably enhanced in the original tissue segment regions, but numerous micro-mineral
deposits were also formed on the coated-fiber networks. When implanted subcutaneously into nude mice, periosteal sheets efficiently
form osteoid around the mineral deposits. These findings suggest that the intricate three-dimensional mesh composed of collagen-coated
fibers substantially augmented the osteogenic activity of human periosteal sheets both in vitro and in vivo. 相似文献
94.
Toru Ikegami Tomotake Morita Shunichi Nakayama Hideyuki Negishi Dai Kitamoto Keiji Sakaki Yasunori Oumi Tsuneji Sano Kenji Haraya Hiroshi Yanagishita 《Journal of chemical technology and biotechnology (Oxford, Oxfordshire : 1986)》2009,84(8):1172-1177
BACKGROUND: Pervaporation employing ethanol‐permselective silicalite membranes as an alternative to distillation is a promising approach for refining low‐concentration bioethanol solutions. However, to make the separation process practicable, it is extremely important to avoid the problems caused by the adsorption of succinate on the membrane during the separation process. In this work, the pervaporation of an ethanol fermentation broth without succinate was investigated, as well as the influence of several fermentation broth nutrient components. RESULTS: Candida krusei IA‐1 produces an extremely low level of succinate. The decrease in permeate ethanol concentration through a silicone rubber‐coated silicalite membrane during the separation of low‐succinate C. krusei IA‐1 fermentation broth was significantly improved when compared with that obtained using Saccharomyces cerevisiae broth. By treating the fermentation broth with activated carbon, bioethanol was concentrated as efficiently as with binary mixtures of ethanol/water. The total flux was improved upto 56% of that obtained from the separation of binary mixtures, compared with 43% before the addition of activated carbon. Nutrients such as peptone, yeast extract and corn steep liquor had a negative effect on pervaporation, but this response was distinct from that caused by succinate. CONCLUSION: For consistent separation of bioethanol from C. krusei IA‐1 fermentation broth by pervaporation, it is useful to treat the low nutrient broth with activated carbon. To further improve pervaporation performance, it will be necessary to suppress the accumulation of glycerol. Copyright © 2009 Society of Chemical Industry 相似文献
95.
Effects of tortuosity and dispersion on the effective thermal conductivity of fluid-saturated porous media are investigated analytically with help of a volume averaging theory. Firstly, a general expression for the effective stagnant thermal conductivity has been derived using a unit cell model, which consists of rectangular solids with connecting arms in an in-line arrangement. The validity of the expression for the stagnant thermal conductivity has been confirmed comparing the present results with available experimental and theoretical data for packed beds, porous foams and wire screens. Secondly, an general expression for the thermal dispersion conductivity has been sought with help of the two energy equations for solid and fluid phases, derived on the basis of a volume averaging theory. It has been shown that the interstitial heat transfer between the solid and fluid phases is closely associated with the thermal dispersion. The resulting expressions for the longitudinal and transverse thermal dispersion conductivities agree well with available experimental data and empirical correlations. 相似文献
96.
Mok-Ryeon Ahn Shigenori Kumazawa Yumiko Usui Jun Nakamura Mitsuo Matsuka Fang Zhu Tsutomu Nakayama 《Food chemistry》2007,101(4):1383-1392
Propolis is a resinous substance collected by honeybees from various plant sources. The composition of propolis depends on time, vegetation, and the area of collection. This study examined the antioxidant activity of propolis from various areas of China: Heilongjiang, Neimongol, Hebei, Shandong, Shanxi, Gansu, Henan, Hubei, Sichuan, Hunan, Yunnan and Hainan. Ethanol extracts of propolis (EEP) were prepared and evaluated for their antioxidant activities by β-carotene bleaching, 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical-scavenging, and 2,2′-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) radical cation decolorization assays. Furthermore, the major constituents in EEP were identified by high-performance liquid chromatography (HPLC) analysis with a photodiode array (PDA) and mass spectrometric (MS) detection, and each component was quantitatively analyzed. All propolis samples except that from Yunnan had relatively strong antioxidant activity accompanied by high total polyphenol contents. Propolis with strong antioxidant activity contained large amounts of antioxidative compounds, such as caffeic acid, ferulic acid and caffeic acid phenethyl ester. On the other hand, propolis from Yunnan and Hainan had compounds not present in propolis from other areas. 相似文献
97.
TOPICS ON FUNDAMENTALS OF PRECISION MACHINING 总被引:1,自引:0,他引:1
K. Nakayama 《Machining Science and Technology》1997,1(2):251-262
Precision machining is becoming increasingly important to meet the needs of technological progress as well as the social requirements of rapid industrialization. An overview on the quality of machined parts from a fundamental viewpoint of machining technology is presented in this article. The parameters that influence dimensional accuracy, surface finish, edge quality, surface integrity and chip control, and the relationship between the various types of chips and cutting forces are included. 相似文献
98.
S Takeno T Daa H Shimoda S Yokoyama I Nakayama Y Uchida 《Canadian Metallurgical Quarterly》1997,47(2-3):95-102
In order to estimate the distribution of Salmonella including Salmonella enteritidis (SE) and SE-antibodies in commercial layer hen flocks in Hokkaido, the northern prefecture of Japan, a survey of spent layer hens was performed, from August 1996 to January 1997. From the three spent hen processing plants, samples of intestines and sera were collected from 740 birds presented for slaughter from 37 flocks of 22 layer hen farms. Intestines from each birds were cultured for Salmonella including Salmonella enteritidis. Serum from each bird was examined for SE-antibody with the enzyme-linked immunosorbent assay (ELISA). Salmonella (any serotype) and Salmonella enteritidis were isolated from 50 (6.8%) and three (0.4%) of 740 birds, respectively, and SE-antibody positive values were recorded from seven birds (0.9%). SE-antibody positive birds did not always indicate isolation of Salmonella enteritidis, however SE-antibody positive hens were demonstrated only from Salmonella enteritidis positive flocks. Salmonellae were isolated from the birds of ten layer hen farms, all of these hens were raised in houses without windows and with automatic feeders. No isolations of salmonella were made from birds raised in houses with windows. From the windowless houses, Salmonellae were isolated from 46 (21.8%) of 260 birds in houses with four to six cages piled up vertically, and from six (2.5%) of 240 samples from the houses with four to five cages piled in a slanting manner. 相似文献
99.
T. Hamada R. Morimo A. Takada Y. Yamashita K. Nakayama K. Nagata T. Yuji 《Journal of Materials Processing Technology》2000,100(1-3)
An experimental study has been carried out to investigate the synergistic effect of Ba4CuPt2O9 compounds on the critical current density of fluorine-doped YBCO superconductors. The Ba4CuPt2O9 compounds were synthesized by a solid state reaction. It was found that the synthesis temperature of the Ba4CuPt2O9 compounds was over 800°C, which was higher than that ever reported previously. In addition, the influence of Ba4CuPt2O9 compounds on the critical current density of YBCO superconductors has been investigated using two types of Ba4CuPt2O9 compounds: one is not heat-treated, i.e. source materials; and the other is heat-treated at 950°C. It was found that the former affected the orientation of the c-axes, but the latter did not have an influence on the orientation of the c-axes, but adversely affected the superconductivity of samples quenched at temperatures above 850°C. 相似文献
100.
Chie Ando Toshimasa Suzuki Youichi Mizuno Hiroshi Kishi Sayuri Nakayama Mamoru Senna 《Journal of Materials Science》2008,43(18):6182-6192
In an attempt to obtain finest possible microparticles of BaTiO3 (BT) with highest possible tetragonality via a solid state route, starting mixtures comprising BaCO3 and TiO2 were subjected to various pretreatments including addition of glycine and mechanical activation. Reaction processes were
monitored by the changes in the weight, crystallinity, and morphology in detail. While mechanical activation with glycine
significantly increased the rate of reaction and homogeneity of the particle size of the product, BT, simultaneous particle
growth of BT was intolerably acute for micro-electronic devices. The fast particle coarsening was predominated by the coalescence
of BT tiny particles formed around titania. A mixture with higher homogeneity was attained by using finer starting materials
under wet mixing, avoiding significant mechanical stressing. Particle growth of BT was suppressed to ca. 100 nm to obtain
fully crystallized BT particles without significant loss of tetragonality and, hence, close to meet our requirements for MLCCs. 相似文献