Effectiveness of Cognitive-Behavioral Treatment for Panic Disorder Versus Treatment as Usual in a Managed Care Setting.

Eighty clients enrolled in a managed care health plan who identified panic disorder as their primary presenting problem were randomly assigned to treatment by a therapist recently trained in a manual-based empirically supported psychotherapy (M. G. Craske, E. Meadows, & D. H. Barlow, 1994) or a therapist conducting treatment as usual (TAU). Participants in both conditions showed significant change from pre- to posttreatment on a number of measures. Those receiving panic control therapy (PCT) showed greater levels of change than those receiving TAU. Among treatment completers, an average of 42.9% of those in PCT and 18.8% in TAU achieved clinically significant change across measures. The results are discussed with reference to the dissemination of PCT and other evidence-based psychotherapies to clinical practice settings. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Recent advances in the production of γ‐valerolactone from biomass‐derived feedstocks via heterogeneous catalytic transfer hydrogenation

γ‐valerolactone (GVL) is an important intermediate chemical with a wide range of applications as fuel, fuel additive and as a green solvent which has received a great deal of attentions from both academia and industry. This review aims to summarise the advances in conversion of renewable feedstocks into GVL through heterogeneous catalytic transfer hydrogenation (CTH) with a strong emphasis on discussing preparation, characterisation and performance of the catalysts in order to provide a better understanding of various catalytic systems and also to compare them in terms of catalytic performance. © 2017 Society of Chemical Industry     

Symmetrical craniofacial hypertrophy in patients with tertiary hyperparathyroidism and high‐dose cinacalcet exposure

We are reporting on a series of two patients with end‐stage renal disease on hemodialysis, presented for surgical parathyroidectomy secondary refractory hyperparathyroidism. Both patients had failed maximized medical managements, including higher‐than‐usual doses of the calcimimetic cinacalcet (270 and 180 mg/day, respectively). On physical exam, both patients had marked symmetrical craniofacial hypertrophy with coarse distortion of facial features, similar in appearance to past reports of Sagliker syndrome. On X‐ray and computed tomographic exam, they had peculiar areas of bone absorption on the skull, imitating the radiologic appearance of multiple myeloma. Bone biopsy of the maxilla, however, did not show the expected brown tumor, but rather described only fibrosis and reactive bone formations. This phenotype developed while being on cinacalcet, progressed despite escalation of therapy, and improved only after parathyroidectomy. Both patients developed massive “hungry bone syndrome” after parathyroidectomy necessitating prolonged IV calcium infusion. This pattern of severe facial distortion likely represented an adverse consequence of severe tertiary hyperparathyroidism, along with supraphysiologic dose of cinacalcet administration and 25‐hydroxy vitamin D deficiency in sensitive individuals. The genetic base of this observation remained unexplained.     

Governments' Ability to Assist Nationals in Disasters Abroad: What Do We Know about Consular Emergency Management?

This review draws attention to the need for consolidated inquiry into large‐scale consular emergency management. Occurring outside national borders, these low‐probability but high‐impact events affect a large number of national citizens. They challenge governments' crisis management systems, and direct public and government attention to a sector that has been largely overlooked in public administration literature – consular affairs. This review brings together the relevant literature on consular assistance and looks further afield to find analysis of emergency responses in case studies of three major consular emergencies. Three underlying themes emerge, central to a more nuanced understanding of the government response to large‐scale emergencies affecting citizens abroad.     

Evaluation of a cloud cover based model for estimation of hourly global solar radiation in Western Canada

Cloud cover based solar radiation models are relatively simple and convenient as the models require the input of cloud cover data which are mostly available from the meteorological stations. In this study, the performance of a cloud cover based solar radiation model (Kasten–Czeplak model) with original or locally fitted coefficients was evaluated for estimating the hourly global solar radiation for four different locations in Western Canada. The average value of R², mean bias error, and root mean square error are 0.69, ?61.6, and 157.9?W?m^?2, respectively, for the model with original coefficients, whereas 0.82, 4.4, 107.1?W?m^?2 with locally fitted coefficients. Results show that the Kasten–Czeplak model with locally fitted coefficients satisfactorily estimated the hourly solar radiation of four different locations in Western Canada. Also, the results indicate that the model with original coefficients has very limited accuracy under intermediate cloud cover conditions.     

In Situ Analysis of the Thermal Evolution of Electrodeposited Fe-C Coatings

Metallurgical and Materials Transactions A - Fe-C coatings with a high amount of carbon were electrodeposited from an iron-sulfate electrolyte. Citric acid as an additive in the electrolyte not...     

Development and comparison of loop-mediated isothermal amplification and quantitative polymerase chain reaction assays for the detection of Mycoplasma bovis in milk

Bovine mastitis is an economic burden for dairies worldwide. Mycoplasma species, and especially Mycoplasma bovis, are among the most important causative agents, and rapid, precise, and low-cost methods for Mycoplasma detection are urgently needed. For this purpose, loop-mediated isothermal amplification (LAMP) and quantitative PCR (qPCR) assays were developed and compared. The LAMP assay was designed and primer concentrations optimized to M. bovis oppD, encoding oligopeptide permease D. For qPCR, a Taqman assay (Applied Biosystems, Carlsbad, CA) targeting M. bovis gltX, encoding glutamate transfer RNA ligase, was optimized for primer concentration, annealing temperature, and DNA polymerase. Both assays were similarly sensitive, with a detection limit of approximately 10⁴ to 10⁵ M. bovis cells/mL. Both assays were also successful in confirming M. bovis identity in laboratory culture suspensions and in bovine milk. The LAMP and qPCR assays combined with the MoBio DNA extraction kit (MoBio Laboratories Inc., Carlsbad, CA) resulted in the correct detection of 13 out of 13 M. bovis isolates and 14 out of 16 M. bovis-positive milk samples collected from commercial dairies in California. When combined with the PrepMan Ultra reagent (Applied Biosystems), the qPCR assay resulted in confirming 21 out of 21 M. bovis-positive milk samples. Comparison of the assays to milk containing either Mycoplasma arginini, Mycoplasma bovigenitalium, Mycoplasma californicum, M. alkalescens, or Acholeplasma laidlawii or milk lacking any detectable Mycoplasma species or relatives resulted in 3 out of 17 (LAMP with MoBio), 1 out of 17 (qPCR with MoBio), and 2 out of 36 (qPCR with PrepMan Ultra) false positives. Overall, the qPCR assay was more robust than LAMP and could be used on DNA recovered from milk prepared with the PrepMan Ultra reagent, a method that does not include a DNA purification step. The use of this qPCR method enables M. bovis detection in bovine milk in 40 to 55 min, and therefore provides new opportunities to accelerate and simplify M. bovis detection in unpasteurized milk to reduce the incidence of M. bovis mastitis outbreaks.