Training psychologists for hospital practice: A proposal.

Hospital practice has become increasingly important for psychologists over the past decade. However, expanded opportunities for practice require training for competency. The authors propose developing a comprehensive, systematic, and flexible program of training for hospital practice in psychology including graduate course work, supervised practicum experience, and opportunities for retraining. Recommendations for certification in hospital practice, credentialing and privileging, and continuing education are included. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Reverse logistics network design with stochastic lead times

This work is concerned with the efficient design of a reverse logistics network using an extended version of models currently found in the literature. Those traditional, basic models are formulated as mixed integer linear programs (MILP-model) and determine which facilities to open that minimize the investment, processing, transportation, disposal and penalty costs while supply, demand and capacity constraints are satisfied. However, we show that they can be improved when they are combined with a queueing model because it enables to account for (1) some dynamic aspects like lead time and inventory positions, and (2) the higher degree of uncertainty inherent to reverse logistics. Since this extension introduces nonlinear relationships, the problem is defined as a mixed integer nonlinear program (MINLP-model). Due to this additional complexity, the MINLP-model is presented for a single product-single-level network. Several examples are solved with a genetic algorithm based on the technique of differential evolution.     

Hierarchical image segmentation based on similarity of NDVI time series

Although a variety of hierarchical image segmentation procedures for remote sensing imagery have been published, none of them specifically integrates remote sensing time series in spatial or hierarchical segmentation concepts. However, this integration is important for the analysis of ecosystems which are hierarchical in nature, with different ecological processes occurring at different spatial and temporal scales. Therefore, the objective of this paper is to introduce a multi-temporal hierarchical image segmentation (MTHIS) methodology to generate a hierarchical set of segments based on spatial similarity of remote sensing time series. MTHIS employs the similarity of the fast Fourier transform (FFT) components of multi-seasonal time series to group pixels with similar temporal behavior into hierarchical segments at different scales. Use of the FFT allows the distinction between noise and vegetation related signals and increases the computational efficiency. The MTHIS methodology is demonstrated on the area of South Africa in an MTHIS protocol for Normalized Difference Vegetation Index (NDVI) time series. Firstly, the FFT components that express the major spatio-temporal variation in the NDVI time series, the average and annual term, are selected and the segmentation is performed based on these components. Secondly, the results are visualized by means of a boundary stability image that confirms the accuracy of the algorithm to spatially group pixels at different scale levels. Finally, the segmentation optimum is determined based on discrepancy measures which illustrate the correspondence of the applied MTHIS output with landcover-landuse maps describing the actual vegetation. In future research, MTHIS can be used to analyze the spatial and hierarchical structure of any type of remote sensing time series and their relation to ecosystem processes.     

A well-based reverse-phase protein array applicable to extracts from formalin-fixed paraffin-embedded tissue

Proteomic analysis of formalin-fixed paraffin-embedded (FFPE) tissue offers significant diagnostic utility but is complicated due to the high level of covalently crosslinked proteins arising from formalin fixation. To address these challenges, we developed a reliable protein extraction method for FFPE tissue, based on heat-induced antigen retrieval within a pressure cooker. The protein extraction yield from archival FFPE tissue section is approximately 90% of that recovered from frozen tissue. This method demonstrates preservation of immunoreactivity and recovery of full-length proteins by Western blotting. Additionally, we developed a well-based RP protein array platform utilizing an electrochemiluminescence detection system. Protein samples derived from FFPE tissue by means of laser capture dissection, with as few as 500 shots demonstrate measurable signal differences for different proteins. The lysates coated to the array plate, remain stable over 1?month at room temperature. Theses data suggest that this new protein-profiling platform coupled with the protein extraction method can be used for molecular profiling analysis in FFPE tissue, and contribute to the validation and development of biomarkers in clinical studies.     

Robust M-estimation of multivariate GARCH models

The Gaussian quasi-maximum likelihood estimator of Multivariate GARCH models is shown to be very sensitive to outliers in the data. A class of robust M-estimators for MGARCH models is developed. To increase the robustness of the estimators, the use of volatility models with the property of bounded innovation propagation is recommended. The Monte Carlo study and an empirical application to stock returns document the good robustness properties of the M-estimator with a fat-tailed Student t loss function.     

电机——被忽略的资产

电机是绝大多数设备的驱动设备。电机的可靠性和有效性会影响到工厂整个生产业务,能严重影响企业生产能力,但却是经常被忽视的资产,在许多计划维修项目中被排除在外。现在,由于种种原因,这种状况愈演愈烈,包括工厂维护工人对电机知识的缺乏。在笔者拜访生产车间和电机维修厂时,经常听到抱怨说缺乏专业工人。最近看了一个简单的电机绕组绝缘测试,很惊讶地发现技术人员不知道需要进行温度校准,