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51.
Anticipating Cutoff Diameters in Deterministic Lateral Displacement (DLD) Microfluidic Devices for an Optimized Particle Separation 下载免费PDF全文
Eloise Pariset Catherine Pudda François Boizot Nicolas Verplanck Jean Berthier Aurélie Thuaire Vincent Agache 《Small (Weinheim an der Bergstrasse, Germany)》2017,13(37)
Deterministic lateral displacement (DLD) devices enable to separate nanometer to micrometer‐sized particles around a cutoff diameter, during their transport through a microfluidic channel with slanted rows of pillars. In order to design appropriate DLD geometries for specific separation sizes, robust models are required to anticipate the value of the cutoff diameter. So far, the proposed models result in a single cutoff diameter for a given DLD geometry. This paper shows that the cutoff diameter actually varies along the DLD channel, especially in narrow pillar arrays. Experimental and numerical results reveal that the variation of the cutoff diameter is induced by boundary effects at the channel side walls, called the wall effect. The wall effect generates unexpected particle trajectories that may compromise the separation efficiency. In order to anticipate the wall effect when designing DLD devices, a predictive model is proposed in this work and has been validated experimentally. In addition to the usual geometrical parameters, a new parameter, the number of pillars in the channel cross dimension, is considered in this model to investigate its influence on the particle trajectories. 相似文献
52.
Kendra L. Van Buren François M. Hemez 《International journal for numerical methods in engineering》2016,105(5):351-371
This work proposes a method for statistical effect screening to identify design parameters of a numerical simulation that are influential to performance while simultaneously being robust to epistemic uncertainty introduced by calibration variables. Design parameters are controlled by the analyst, but the optimal design is often uncertain, while calibration variables are introduced by modeling choices. We argue that uncertainty introduced by design parameters and calibration variables should be treated differently, despite potential interactions between the two sets. Herein, a robustness criterion is embedded in our effect screening to guarantee the influence of design parameters, irrespective of values used for calibration variables. The Morris screening method is utilized to explore the design space, while robustness to uncertainty is quantified in the context of info‐gap decision theory. The proposed method is applied to the National Aeronautics and Space Administration Multidisciplinary Uncertainty Quantification Challenge Problem, which is a black‐box code for aeronautic flight guidance that requires 35 input parameters. The application demonstrates that a large number of variables can be handled without formulating simplifying assumptions about the potential coupling between calibration variables and design parameters. Because of the computational efficiency of the Morris screening method, we conclude that the analysis can be applied to even larger‐dimensional problems. (Approved for unlimited, public release on October 9, 2013, LA‐UR‐13‐27839, Unclassified.) Copyright © 2015 John Wiley & Sons, Ltd. 相似文献
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54.
Single‐Molecule Magnets: Giant Hysteresis of Single‐Molecule Magnets Adsorbed on a Nonmagnetic Insulator (Adv. Mater. 26/2016) 下载免费PDF全文
55.
Corrosion of steel in reinforced concrete structures is a recurrent problem affecting civil engineering structures and costing the world billions of dollars per year. This physical phenomenon mainly results from chloride ingress or concrete carbonation. Corrosion can be diagnosed through a nondestructive method such as half-cell potential measurements. The present paper studies this method on a reinforced concrete wall containing eighteen unconnected steel bars and subjected to chloride-induced macrocell corrosion. Three corrosion systems with different configurations of connections between the steel bars are generated, involving three different anode-to-cathode surface ratios. Then, half-cell potential variations are observed versus macrocell corrosion current. The results lead to a critical discussion regarding the physical relevance of the usual potential threshold method to detect corroding rebars in reinforced concrete structures. In addition, the experiments demonstrate that electrical continuity between reinforcing steel bars is not necessary to get meaningful information about the macrocell corrosion system. At last, the paper show that the electric field (potential gradient) relative to a macrocell corrosion system may be measured by connecting the measurement system (reference electrode?+?voltmeter) to any electrochemical system in electrolytic contact with the concrete. 相似文献
56.
Nano Research - The widespread and increasing interest in enhancing biosensing technologies by increasing their sensitivities and lowering their costs has led to the exploration and application of... 相似文献
57.
58.
Béatrice Creusillet François Irigoin 《International journal of parallel programming》1996,24(6):513-546
Many program optimizations require exact knowledge of the sets of array elements that are referenced in or that flow between statements or procedures. Some examples are array privatization, generation of communications in distributed memory machines, or compile-time optimization of cache behavior in hierarchical memory machines. Exact array region analysis is introduced in this article. These regions exactly represent the effects of statements and procedures upon array variables. To represent the flow of these data, we also introduce two new types of array region analyses: in and out regions. The intraprocedural propagation is presented, as well as a general linear framework for interprocedural analyses, which handles array reshapes. The intra- and inter-procedural propagation of array regions is implemented in pips, the interprocedural parallelizer of fortran programs developed at École des mines de Paris. 相似文献
59.
Thomas?Lavergne Tanguy?Urvoy Fran?ois?YvonEmail author 《Language Resources and Evaluation》2011,45(1):25-43
Fake content is flourishing on the Internet, ranging from basic random word salads to web scraping. Most of this fake content
is generated for the purpose of nourishing fake web sites aimed at biasing search engine indexes: at the scale of a search
engine, using automatically generated texts render such sites harder to detect than using copies of existing pages. In this
paper, we present three methods aimed at distinguishing natural texts from artificially generated ones: the first method uses
basic lexicometric features, the second one uses standard language models and the third one is based on a relative entropy
measure which captures short range dependencies between words. Our experiments show that lexicometric features and language
models are efficient to detect most generated texts, but fail to detect texts that are generated with high order Markov models.
By comparison our relative entropy scoring algorithm, especially when trained on a large corpus, allows us to detect these
“hard” text generators with a high degree of accuracy. 相似文献
60.
This work introduces a probabilistic model allowing to compute reputation scores as close as possible to their intrinsic value, according to the model. It is based on the following, natural, consumer-provider interaction model. Consumers are assumed to order items from providers, who each has some intrinsic, latent, “quality of service” score. In the basic model, the providers supply the items with a quality following a normal law, centered on their intrinsic “quality of service”. The consumers, after the reception and the inspection of the item, rate it according to a linear function of its quality - a standard regression model. This regression model accounts for the bias of the consumer in providing ratings as well as his reactivity towards changes in item quality. Moreover, the constancy of the provider in supplying an equal quality level when delivering the items is estimated by the standard deviation of his normal law of item quality generation. Symmetrically, the consistency of the consumer in providing similar ratings for a given quality is quantified by the standard deviation of his normal law of ratings generation. Two extensions of this basic model are considered as well: a model accounting for truncation of the ratings and a Bayesian model assuming a prior distribution on the parameters. Expectation-maximization algorithms, allowing to estimate the parameters based on the ratings, are developed for all the models. The experiments suggest that these models are able to extract useful information from the ratings, are robust towards adverse behaviors such as cheating, and are competitive in comparison with standard methods. Even if the suggested models do not show considerable improvements over other competing models (such as Brockhoff and Skovgaard’s model [12]), they, however, also permit to estimate interesting features over the raters - such as their reactivity, bias, consistency, reliability, or expectation. 相似文献