Coincident indices of exons and introns

In this paper, the coincident index, proposed by W. F. Friedman in cryptology, is made use of in DNA sequence analysis and exon prediction. The coincident index of exons exceeds that of introns by many times, and is mainly affected by window length, which is correlated negatively with the coincident index. An optimal exon prediction scheme was obtained by experimental analysis with an orthogonal table. Besides exons, many other special sites such as tandem repeats can be identified by using the coincident index approach. The application of this approach to the ARV-2 (AIDS associated retrovirus 2) genome found three new possible coding regions and some unusual base composition regions which are probably related to definite biological functions.     

BIMORPH PIEZOELECTRIC ACTUATOR FOR SMALL PIPE ROBOT

An experimental bimorph piezoelectric element (PZT) actuator for small pipe robot is developed. The robot can move in φ20 mm pipe, and can carry a CCD camera for detecting cracks or fine holes on inner surface of pipe. The velocity of the robot can reach 17～22 mm/s for vertical pipe up/down, respectively. Moving principle and its performance characteristics are presented.     

空分设备的酸性腐蚀及预防

以切换式换热器空分设备为例 ,分析了空分设备酸性腐蚀的原因、可能造成的危害 ,提出了预防措施。     

Characterization of mutated transforming growth factor-beta s which possess unique biological properties

Transforming growth factor-beta (TGF-beta) is a potent regulator of cell growth and differentiation. On the basis of the crystal structure of TGF-beta 2, we have designed and synthesized two mutant TGF-beta s, TGF-beta 1 (71 Trp) and TGF-beta 1 (delta 69-73). Although both of these molecules inhibited the growth of Mv1Lu mink lung epithelial cells and LS1034 colorectal cancer cells, which are affected equally by TGF-beta 1 and TGF-beta 2, TGF-beta 1 (delta 69-73) was much less potent than TGF-beta 1 or TGF-beta 1 (71 Trp) at inhibiting the growth of LS513 colorectal cancer cells which are growth-inhibited by TGF-beta 1 but not TGF-beta 2. Both TGF-beta 1 (71 Trp) and TGF-beta 1 (delta 69-73) increased levels of mRNAs for fibronectin and plasminogen activator inhibitor with Mv1Lu cells, whereas only TGF-beta 1 (71 Trp) and not TGF-beta 1 (delta 69-73) up-regulated the mRNA level of carcinoembryonic antigen in LS513 cells. The expression level of carcinoembryonic antigen mRNA in LS1034 cells was not altered by either wild-type or mutant TGF-beta s. Receptor labeling experiments demonstrated that TGF-beta 1 (71 Trp) bound with high affinity to the cell-surface receptors of Mv1Lu, LS1034, and LS513 cells while TGF-beta 1 (delta 69-73) bound effectively to the receptors of Mv1Lu and LS1034 cells but much less to the receptors on LS513 cells.(ABSTRACT TRUNCATED AT 250 WORDS)     

Corticofugal regulation of auditory sensitivity in the bat inferior colliculus

Risk factors for severe acute asthma involve the patient, the environment and the society in general. In addition, there are strong interrelationships between these factors. Personal characteristics linked to acute severe asthma include age (teenagers), denial leading to poor compliance, depression with atypical symptoms in children, and some medical features of asthma associated with increased severity. Environmental factors include airborne allergens, infections, irritants such as air pollutants and passive smoking. Life events have not been extensively studied but are likely to play a predominant role. The social setting, particularly the health care system, acts as an interface between the patient and the environment. Most all asthma deaths are avoidable and related to dysfunctions in the health care system.     

Using thermally stimulated currents to find defective capacitors

BaTiO₃ multilayer capacitors with a nominal capacitance of 3.5nF have been carefully measured using the thermally stimulated current (TSC) technique. When a 300V polarization voltage is applied at room temperature, a new TSC peak appeared in defective sample A after it has been immersed in water. No new peak was found in good-quality sample B after a similar treatment. The accelerated life test shows that sample A hasa much shorter life than sample B in terms of insulation resistance.     

RE／S值对控轧低碳Mn－Nb－RE钢硫化物成分和形貌的影响

用扫描电镜测定了含０．０４１％～０．０７６％ＲＥ的低碳Ｍｎ－Ｎｂ－ＲＥ钢中硫化物的成分、大小和形貌。ＲＥ／Ｓ值为２．８～３．０时，钢中的硫化物充分变质。     

精馏塔静态仿真：Ⅰ.静动态混合数学模型的应用

本文为了克服精馏塔静态仿真不易收敛和初值难以给定等难题，巧妙地利用隐含数值积分方法的特点，将稳态与动态数学模型耦合起来，用以求解高难度的非理想精馏塔静态仿真问题。所得静动态混俣模型大大提高了精馏塔静态仿真的鲁棒性，对于高度非理想精馏塔的仿真尤为有效。通过对某丙烯腈萃取精馏塔的静态仿真，充分证明了这种混合模型化方法的可行性。     

山洪灾害预警准确度与及时度研究

山洪灾害预警准确度与及时度是一对相互矛盾而又联系的重要指标。文章通过对这两项指标的研究和对引发灾害的降雨强度、降雨以及灾害发生的时间资料进行分析,从而获取预警系统建设的基本技术要点和参数,对把握山洪灾害预警系统的设计定位、启用时机和作用评估具有重要作用和意义。     

Output-power-clamped Raman fibre laser with suppression of low-frequency RIN transfer from pump sources

An optical approach is demonstrated for suppressing low-frequency relative intensity noise (RIN) transfer from pump sources to the author's proposed Raman fibre laser (RFL). Low-frequency RIN transfer suppression is accomplished by outputting not the second- but first-order Stokes, which output power is clamped by the lasing second-order Stokes in the cavity and can be easily tuned in a large dynamic range. Thus, this technique fits the RFL for use as pump sources in Raman fibre amplifiers.