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261.
Multi-body dynamics simulation of geometrically exact Cosserat rods   总被引:1,自引:0,他引:1  
In this paper, we present a viscoelastic rod model that is suitable for fast and accurate dynamic simulations. It is based on Cosserat’s geometrically exact theory of rods and is able to represent extension, shearing (‘stiff’ dof), bending and torsion (‘soft’ dof). For inner dissipation, a consistent damping potential proposed by Antman is chosen. We parametrise the rotational dof by unit quaternions and directly use the quaternionic evolution differential equation for the discretisation of the Cosserat rod curvature.  相似文献   
262.
Osteoporosis is characterized by low bone mass and damage to the bone tissue’s microarchitecture, leading to increased fracture risk. Several studies have provided evidence for associations between psychosocial stress and osteoporosis through various pathways, including the hypothalamic-pituitary-adrenocortical axis, the sympathetic nervous system, and other endocrine factors. As psychosocial stress provokes oxidative cellular stress with consequences for mitochondrial function and cell signaling (e.g., gene expression, inflammation), it is of interest whether extracellular vesicles (EVs) may be a relevant biomarker in this context or act by transporting substances. EVs are intercellular communicators, transfer substances encapsulated in them, modify the phenotype and function of target cells, mediate cell-cell communication, and, therefore, have critical applications in disease progression and clinical diagnosis and therapy. This review summarizes the characteristics of EVs, their role in stress and osteoporosis, and their benefit as biological markers. We demonstrate that EVs are potential mediators of psychosocial stress and osteoporosis and may be beneficial in innovative research settings.  相似文献   
263.
Young children spend a substantial part of their waking time in preschools. It is therefore important to reduce the load of hazardous semivolatile organic compounds (SVOCs) in the preschools’ indoor environment. The presence and levels of five SVOC groups were evaluated (1) in a newly built preschool, (2) before and after renovation of a preschool, and (3) in a preschool where SVOC-containing articles were removed. The new building and the renovation were performed using construction materials that were approved with respect to content of restricted chemicals. SVOC substance groups were measured in indoor air and settled dust and included phthalates and alternative plasticizers, organophosphate esters (OPEs), brominated flame retardants, and bisphenols. The most abundant substance groups in both indoor air and dust were phthalates and alternative plasticizers and OPEs. SVOC concentrations were lower or of the same order of magnitude as those reported in comparable studies. The relative Cumulative Hazard Quotient (HQcum) was used to assess the effects of the different reduction measures on children's SVOC exposure from indoor air and dust in the preschools. HQcum values were low (1.0–6.1%) in all three preschools and decreased further after renovation and article substitution. The SVOCs concentrations decreased significantly more in the preschool renovated with the approved building materials than in the preschool where the SVOC-containing articles were removed.  相似文献   
264.
研究了氟等离子体离子注入对Au/Ni/n-GaN二极管的电学和光学特性的影响。结果表明,离子注入后,器件的反向泄漏电流从1×10-5 A 降低至1×10-12 A(偏压为 -5 V),整流特性获得显著提高;器件的内建势垒高度从1.30 eV 增至3.22 eV,接近GaN的禁带宽度,表明最高价带处产生了高浓度的空穴;器件能够实现紫外光探测,在偏压为 -5 V时,紫外/可见光抑制比约为1×103,最高响应度约为0.045 A/W,最大外量子效率约为15.5%,瞬态响应平均衰减时间常数约为35 ms。由此可见,氟等离子体离子注入是调节Au/Ni/n-GaN二极管电学和光学性能的有效手段之一。  相似文献   
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266.
目的 制备均匀性及稳定性均满足要求的克罗诺杆菌属(阪崎肠杆菌)检验能力验证样品,用于组织能力验证考核.方法 通过生化及基质辅助激光解吸电离飞行时间质谱方法鉴定背景菌株及所使用的克罗诺杆菌属(阪崎肠杆菌)菌株.采用冷冻干燥技术制备均匀性及稳定性均满足要求且各种菌含量为104 CFU/瓶的能力验证菌球.依据CNAS-GL0...  相似文献   
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