Precision Measurements of Time Characteristics of ETL9351 Photomultipliers

The measured characteristics of 2200 photomultiplier tubes (PMTs) for the future Borexino experiment are considered to provide the most complete information for evaluating the time characteristics of ETL9351 PMTs with a high precision. The unique time characteristics of the apparatus used and the large statistics obtained during the tests of the PMTs allow the fine structure of the PMT time response to be resolved. A method for obtaining the probability density function of the single-photoelectron counting from the experimental data is proposed and used to derive the PMT average characteristics. For the first time, an analytical model is proposed to describe all the features of the single-photoelectron PMT time response. The origin of small-amplitude pulses, as well as the shape of the time spectra of PMT, is explained.     

Optimization of properties in a rubber compound containing a ternary polymer blend using response surface methodology

In order to find the best combination of three synthetic rubbers, that is, styrene‐butadiene rubber (SBR) grade 1712, SBR grade 1721 and high‐1,4‐cis polybutadiene, that produce a compound with specific end‐use properties, a statistical experimental design is proposed in this work. The design consists of ten mixtures containing specific amounts of total styrene and BR content. A number of properties are tested in each mixture, selecting those related to requirements for the tread of a high performance tire: glass transition temperature (T_g), the ratio between the viscous modulus and the elastic modulus (tanδ@60 °C), Mooney viscosity, and the tensile properties. The values obtained for each property are fit to statistically significant models, obtaining the respective response surfaces. These are next used to define a desirable formulation with the optimal ratio of each rubber, and finally the optimized formulation is validated by comparing the experimental and predicted values for each modeled property. © 2018 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2018 , 135, 46548.     

Analysis of punctures in DNA self-assembly under forward growth

This paper deals with the characterization and analysis of intentionally induced punctures on a DNA self-assembly. Based on forward growth, punctures are utilized to remove errors in DNA tiles from the self-assembly. Initially, a Markov model is proposed by considering different types of punctures under various bonding conditions in the tiles. For different values of on and off rates (as corresponding to the parameters G(se) and G(mc)), it is shown that the proposed models can assess the types of puncture for removing mismatched tiles as errors. Subsequently, a novel model of puncturing is introduced to establish the condition by which a generic aggregate can utilize punctures for error resilience. It is proven that by using the correct puncture(s), errors as frozen mismatched tiles are moved toward the boundaries, thus ensuring the generation of the target assembly and ease in removal of the errors. As an example, the Sierpinski tile set is analyzed based on the proposed models to fully assess the appropriate type of puncture for this pattern. Simulation results are provided as evidence that the proposed models are effective.     

Design verification of FPGA implementations

This approach uses the criterion of equivalent classes to establish the equivalence between two circuits and designs. Combining simulation and automatic test pattern generation, it exploits similarities among designs to assess logical equivalence quickly and reliably     

Molecular analysis of 11q13 breakpoints in multiple myeloma

The t(11;14)(q13;q32) chromosomal translocation, which is the hallmark of mantle cell lymphoma (MCL), is found in approximately 30% of multiple myeloma (MM) tumors with a 14q32 translocation. Although the overexpression of cyclin D1 has been found to be correlated with MM cell lines carrying the t(11;14), rearrangements of the BCL-1/cyclin D1 regions frequently involved in MCL rarely occur in MM cell lines or primary tumors. To test whether specific 11q13 breakpoint clusters may occur in MM, we investigated a representative panel of primary tumors by means of Southern blot analysis using probes derived from MM-associated 11q13 breakpoints. To this end, we first cloned the breakpoints and respective germ-line regions from a primary tumor and the U266 cell line, as well as the germ-line region from the KMS-12 cell line. DNA from 50 primary tumors was tested using a large panel of probes, but a rearrangement was detected in only one case using the KMS-12 breakpoint probe. Our results confirm previous findings that the 11q13 breakpoints in MM are scattered throughout the 11q13 region encompassing the cyclin D1 gene, thus suggesting the absence of 11q13 breakpoint clusters in MM.     

Work-related ladder fall fractures: identification and diagnosis validation using narrative text

OBJECTIVE: To identify ladder-related fracture injuries and determine how ladder fall fractures differ from other ladder-related injuries. METHODS: Ladder-related fracture cases were identified using narrative text and coded data from workers' compensation claims. Potential cases were identified by text searches and verified with claim records. Injury characteristics were compared using proportionate injury ratios. RESULTS: Of 9826 ladder-related injuries, 7% resulted in fracture cases. Falls caused 89% of fractures and resulted in more medical costs and disability days than other injuries. Frequent mechanisms were ladder instability (22%) and lost footing (22%). Narrative text searches identified 17% more fractures than injury codes alone. Males were more likely to sustain a fall fracture than other injuries; construction workers were most likely, and retail workers were the least likely to sustain fractures. CONCLUSIONS: Fractures are an important injury from ladder falls, resulting more serious consequences than other ladder-related injuries. Text analysis can improve the quality and utility of workers compensation data by identifying and understanding injury causes. Proportionate injury ratios are also useful for making cross-group comparisons of injury experience when denominator data are not available. Greater attention to risk factors for ladder falls is needed for targeting interventions.     

Sample treatment considerations in the analysis of organic colorants by surface-enhanced Raman scattering

The introduction of surface-enhanced Raman spectroscopy (SERS) in the field of cultural heritage has significantly improved the analysis of the organic dyes and their complexes that have been used as textile dyes and pigments in paintings and other polychrome works of art since antiquity. Over the last five years, a number of different procedures have been developed by various research groups. In this Article, we evaluate the effect of pretreating samples by exposing them to hydrofluoric acid (HF) vapor prior to SERS analysis, a step designed to hydrolyze the dye-metal complexes and increase analyte adsorption on the nanosized metallic support, thus enhancing the SERS signal. Materials studied include pure colorants, commercial lake pigments, and fibers from dyed textiles, as well as actual aged samples, such as microscopic fragments of lakes on paper and ancient pigments and glazes from several works of art, covering a wide range of time, from the second century B.C. to the early 20th century. In each case, SERS spectra obtained with or without HF hydrolysis were critically evaluated. The pretreatment with HF vapor resulted in faster analysis and increased sensitivity in most cases, with the exception of dyed silk fibers, where silk protein hydrolyzates were found to interfere with SERS analysis. As a final point, a two-step procedure including SERS on untreated and treated samples is proposed as a standard approach: by analyzing a sample first without hydrolysis, and then, following removal of the colloid, upon HF treatment, the best and most reliable results for a great number of dyes and substrates are assured.     

Automated Clock Comparisons and Time Scale Generation in the SIM Region

The second, the base unit of time interval in the International System, is defined in terms of the two hyperfine states of the Cesium atom ground-state energy level. This definition has so far served the metrology community well, and the uncertainty of the best realization of the second has improved by a rate of about one order of magnitude per decade over the past 50?years, reaching a current level of a few parts in 10¹⁶ [1]. This continual reduction in uncertainty has increased the level of performance expected from both time and frequency transfer systems and from the time standards maintained by national metrology institutes (NMIs). During recent years, an automated time comparison network has been developed within the Sistema Interamericano de Metrologia (SIM), a regional metrology organization. The SIM Time Network (SIMTN) allows NMIs to compare their time scales via the Global Positioning System common-view and all-in-view time transfer techniques, and makes results available through the Internet in near real time [2]. The SIMTN has proven to be robust and reliable, and the uncertainty of its comparisons is similar to the uncertainty of the key comparisons published by the Bureau International des Poids et Mesures in its monthly Circular T document. The large number of geographically dispersed clocks measured by the SIMTN made it attractive to develop a SIM time scale (SIMT), which is computed in near real time and immediately made available to the general public via the Internet. This rapid computation allows contributing laboratories to easily monitor their time scales, and to quickly detect short term fluctuations in stability and accuracy. This paper discusses both the SIMTN and the SIMT, focusing primarily on the SIMT algorithm and the results of its performance.     

Sol–gel derived 45S5 bioglass: synthesis, microstructural evolution and thermal behaviour

In this work, the 45S5 bioactive glass was synthesized through an aqueous sol-gel method. Characteristic functional groups were evidenced by Fourier transform infrared spectroscopy, the thermal behaviour was investigated by thermogravimetric and differential thermal analysis, crystallization kinetics and phase evolution were followed by X-ray diffraction measurements. The sintering behaviour of the sol-gel derived 45S5 was then studied by dilatometry and the microstructural evolution was followed step-by-step, interrupting the thermal cycle at different temperatures. In vitro dissolution tests were performed in order to assess the degradation behaviour of sol-gel derived 45S5 samples thermally treated at different temperatures. A relevant influence of the calcination conditions (namely, dwelling time and temperature) of the as-prepared powder on the phase appearance and its sintering behaviour as well as on the porosity features, in terms of pore dimension and interconnectivity, of the fired materials was stated.     

Steel Hexagonal Honeycomb Core Equivalent Elastic Moduli for Bridge Deck Sandwich Panels

Glass fiber-reinforced polymer (GFRP) materials possess inherently high strength-to-weight ratios, but their effective elastic moduli are low relative to civil engineering (CE) construction materials. While elastic modulus may be comparable to that of some CE materials, the lower shear modulus adversely affects stiffness. As a result, serviceability issues are what govern GFRP deck design in the CE bridge industry. An innovative solution to increase the stiffness of a commercial GFRP reinforced-sinusoidal honeycomb sandwich panel was proposed; this solution would completely replace the GFRP honeycomb core with a hexagonal honeycomb core constructed from commercial steel roof decking. The purpose of this study was to perform small-scale tests to characterize the steel hexagonal honeycomb core equivalent elastic moduli in an effort to simplify the modeling of the core. The steel core equivalent moduli experimental results were compared with theoretical hexagonal honeycomb elastic modulus equations from the literature, demonstrating the applicability of the theoretical equations to the steel honeycomb core. Core equivalent elastic modulus equations were then proposed to model and characterize the steel hexagonal honeycomb as applicable to sandwich panel design. The equivalent honeycomb core will enable an efficient sandwich panel stiffness design technique, both for structural analysis methods (i.e., hand calculations) and finite-element analysis procedures.