Mental state decoding abilities in young adults with borderline personality disorder traits.

Previous studies have demonstrated that patients with borderline personality disorder (BPD) tend to misattribute malevolence to benign social stimuli, including facial expressions. Yet, facial emotion recognition studies examining those with BPD have yielded mixed results, with some studies showing impaired accuracy and others demonstrating enhanced accuracy in the recognition of emotions or mental states. The current study examined the ability to decode mental states from photographs of just the eye region of faces in a nonclinical sample of young adults who exhibited BPD traits (high BPD) compared with those who did not (low BPD). Group differences in mental state decoding ability depended on the valence of the stimuli. The high-BPD group performed better for negative stimuli compared with the low-BPD group, but did not perform significantly different from the low-BPD group for stimuli of neutral or positive valence. The high-BPD group also demonstrated a response bias for attributing negative mental states to facial stimuli. In addition, findings suggested that the group difference in accuracy for negative stimuli could not be explained by response bias, because the group difference in response bias for negative stimuli did not reach significance. These findings suggest that BPD traits may be associated with enhanced ability to detect negative emotions and a bias for attributing negative emotions to nonnegative social stimuli. (PsycINFO Database Record (c) 2011 APA, all rights reserved)     

Biocompatible carbohydrate-functionalized stainless steel surfaces: a new method for passivating biomedical implants

A convenient method for passivating and functionalizing stainless steel is described. Several methods of coating stainless steel (SS) samples with silica were investigated and of these methods, a thin (less than 15 nm thick) layer of silica created by atomic layer deposition (ALD) was found to give superior performance in electrochemical testing. These interfaces were then used as a platform for further functionalization with molecules of biological interest. Specifically, the SS samples were functionalized with biologically significant carbohydrates [N-acetyl-D-glucosamine (GlcNAc) and D-galactose (Gal)] that contain trialkoxysilane derivatives as chemical handles for linking to the surface. The presence and biological availability of these moieties on the silica coated SS were confirmed by XPS analysis and an enzyme-linked lectin assay (ELLA) using complementary lectins that specifically recognize the surface-bound carbohydrate. This method has the potential of being adapted to the functionalization of stainless steel biomedical implants with other biologically relevant carbohydrates.     

Effects of diet type and supplementation of glucosamine, chondroitin, and MSM on body composition, functional status, and markers of health in women with knee osteoarthritis initiating a resistance-based exercise and weight loss program

Background

The purpose of this study was to determine whether sedentary obese women with knee OA initiating an exercise and weight loss program may experience more beneficial changes in body composition, functional capacity, and/or markers of health following a higher protein diet compared to a higher carbohydrate diet with or without GCM supplementation.

Methods

Thirty sedentary women (54 ± 9 yrs, 163 ± 6 cm, 88.6 ± 13 kg, 46.1 ± 3% fat, 33.3 ± 5 kg/m²) with clinically diagnosed knee OA participated in a 14-week exercise and weight loss program. Participants followed an isoenergenic low fat higher carbohydrate (HC) or higher protein (HP) diet while participating in a supervised 30-minute circuit resistance-training program three times per week for 14-weeks. In a randomized and double blind manner, participants ingested supplements containing 1,500 mg/d of glucosamine (as d-glucosamine HCL), 1,200 mg/d of chondroitin sulfate (from chondroitin sulfate sodium), and 900 mg/d of methylsulfonylmethane or a placebo. At 0, 10, and 14-weeks, participants completed a battery of assessments. Data were analyzed by MANOVA with repeated measures.

Results

Participants in both groups experienced significant reductions in body mass (-2.4 ± 3%), fat mass (-6.0 ± 6%), and body fat (-3.5 ± 4%) with no significant changes in fat free mass or resting energy expenditure. Perception of knee pain (-49 ± 39%) and knee stiffness (-42 ± 37%) was decreased while maximal strength (12%), muscular endurance (20%), balance indices (7% to 20%), lipid levels (-8% to -12%), homeostasis model assessment for estimating insulin resistance (-17%), leptin (-30%), and measures of physical functioning (59%), vitality (120%), and social function (66%) were improved in both groups with no differences among groups. Functional aerobic capacity was increased to a greater degree for those in the HP and GCM groups while there were some trends suggesting that supplementation affected perceptions of knee pain (p < 0.08).

Conclusions

Circuit style resistance-training and weight loss improved functional capacity in women with knee OA. The type of diet and dietary supplementation of GCM provided marginal additive benefits.

Trial Registration

ClinicalTrials.gov: NCT01271218     

Expanding a performance improvement initiative in critical care from hospital to system

BACKGROUND: Concern about the expense and effects of intensive care prompted the development and implementation of a hospital-based performance improvement initiative in critical care at North Shore University Hospital, Manhasset, New York, a 730-bed acute care teaching hospital. THE HOSPITAL-BASED PERFORMANCE IMPROVEMENT INITIATIVE IN CRITICAL CARE: The initiative was intended to use a uniform set of measurements and guidelines to improve patient care and resource utilization in the intensive care units (ICUs), to establish and implement best practices (regarding admission and discharge criteria, nursing competency, unplanned extubations, and end-of-life care), and to improve performance in the other hospitals in the North Shore-Long Island Jewish Health System. In the medical ICU, the percentage of low-risk (low-acuity) patients was reduced from 42% to 22%. ICU length of stay was reduced from 4.6 days to 4.1 days. IMPLEMENTING THE CRITICAL CARE PROJECT SYSTEMWIDE: A system-level critical care committee was convened in 1996 and charged with replicating the initiative. By and large, system efforts to integrate and implement policies have been successful. The critical care initiative has provided important comparative data and information from which to gauge individual hospital performance. DISCUSSION: Changing the critical care delivered on multiple units at multiple hospitals required sensitivity to existing organizational cultures and leadership styles. Merging organizational cultures is most successful when senior leadership set clear expectations that support the need for change. The process of collecting, trending, and communicating quality data has been instrumental in improving care practices and fostering a culture of safety throughout the health care system.     

Are trauma victims susceptible to "false memories?"

Laboratory studies using word-list paradigms have provided evidence that nontraumatized individuals falsely recall or recognize events that never occurred. In the present study, H. L. Roediger and K. B. McDermott's false-memory paradigm (1995) was utilized to examine possible source monitoring deficits in individuals with PTSD. Traumatized individuals with PTSD were compared with traumatized individuals without PTSD and with nontraumatized control participants. Participants heard lists of related words (e.g., bed, night) that were associates of a critical nonpresented word (e.g., sleep) and were given immediate free recall and later recognition tests. Traumatized participants with and without PTSD generated more false recalls of critical nonpresented words than did nontraumatized participants. False recall was related to trait anxiety and PTSD severity. The results are consistent with a general source-monitoring deficit in trauma-exposed individuals. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

The frequency domain approach in virtual fatigue estimation of non-linear systems: The problem of non-Gaussian states of stress

The use of the frequency domain approach in the virtual estimation of mechanical component fatigue life under random loads is related to two conditions regarding the dynamic behaviour of components and the state of stress. The mechanical system must have linear behaviour and the probability density function of stress must be Gaussian, respectively. Obviously, these conditions are not independent, because there is a close tie between the transformations induced by the system to the random inputs and stress distribution.The rigorous procedure for the extension of these hypotheses is not available and only approximated approaches can be used: normally these are based on a corrective coefficient to the narrow-band formula.The main goal of this report is to suggest a separation of the effects on the corrective coefficient. In this manner, the global coefficient can be seen as the product between a partial coefficient related only to the wide-band effects of stress power spectral density function and another one dependent on non-normality indices of stress probability density function. A meaningful application has been investigated to validate the practical employment of this approach. By this example the authors also defined an original analytical expression of a corrective coefficient for Gaussian damage; however, the formulation has to be improved by other applications, because its validity is tested only on a too much limited domain of Kurtosis values. Moreover, the authors suggest that a modal approach to the stress recovery procedure of a flexible body might be an interesting way to the rapid identification of non-Gaussianity indices in the analysis of frequency and time domain dynamics. For this reason, they believe that the investigation of tying the stress non-Gaussianity to the non-Gaussianity of the component modal coordinates to be useful.     

The contribution of children’s self-regulation and classroom quality to children’s adaptive behaviors in the kindergarten classroom.

In this study, the authors examined the extent to which children’s self-regulation upon kindergarten entrance and classroom quality in kindergarten contributed to children’s adaptive classroom behavior. Children’s self-regulation was assessed using a direct assessment upon entrance into kindergarten. Classroom quality was measured on the basis of multiple classroom observations during the kindergarten year. Children’s adaptive classroom behavior in kindergarten was assessed through teacher report and classroom observations: Teachers rated children’s cognitive and behavioral self-control and work habits during the spring of the kindergarten year; observers rated children’s engagement and measured off-task behavior at 2-month intervals from November to May. Hierarchical linear models revealed that children’s self-regulation upon school entry in a direct assessment related to teachers’ report of behavioral self-control, cognitive self-control, and work habits in the spring of the kindergarten year. Classroom quality, particularly teachers’ effective classroom management, was linked to children’s greater behavioral and cognitive self-control, children’s higher behavioral engagement, and less time spent off-task in the classroom. Classroom quality did not moderate the relation between children’s self-regulation upon school entry and children’s adaptive classroom behaviors in kindergarten. The discussion considers the implications of classroom management for supporting children’s early development of behavioral skills that are important in school settings. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

School readiness among children with varying histories of language difficulties.

This study tested the hypotheses that (a) persistent language difficulties during childhood would predict lower school readiness and (b) language difficulties present just prior to school entry would predict lower school readiness beyond any effects of persistence. The study involved examining indicators of school readiness collected at kindergarten for children exhibiting various histories of language ability based on language measures collected at 15, 24, 36, and 54 months by the National Institute of Child Health and Human Development's Early Child Care Research Network. Children (N = 1,064) were classified according to whether they exhibited expressive or receptive language difficulties at each time point measured. The relation between persistence and timing of these difficulties to each kindergarten outcome was studied through a common factor approach for categorical outcomes. Persistence of language difficulties was not generally related to kindergarten outcomes. However, a robust effect was found for timing of language difficulties: Children who exhibited language difficulties at 54 months exhibited significantly depressed performance on measures of school readiness. Findings are discussed in terms of current policy and research concerning kindergarten readiness for children exhibiting risk. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Evaluation of the thiamine dose-response relationship for lake trout (Salvelinus namaycush) fry using an individual based model

Substantial natural reproduction of lake trout (Salvelinus namaycush) has not been achieved in the Great Lakes, except for Lake Superior and a few areas in Lake Huron, despite continued stocking efforts. Low thiamine levels in lake trout eggs, which can result in lethal and sublethal impacts (thiamine deficiency complex, TDC) on fry, may contribute to widespread recruitment failure in lake trout populations. We hypothesized that incorporation of sublethal impacts into dose-response curves would result in estimates of EC50s (median lethal concentrations) for fry greater than the estimates that rely only on acute mortality and that predation would exacerbate thiamine effects. To investigate the sublethal effects of TDC (prey capture success and predation mortality) on cohort growth and survival, we developed an individual-based model for lake trout fry. The model tracks daily activities, including consumption, respiration, growth, and mortality, of lake trout from hatch until fry reach a length of 33?mm when we assume fry feed naturally and thiamine effects are minimized. Model output with sublethal impacts resulted in an EC50 (7.3?nmol/g) that was greater than published studies that are limited to acute mortality (1.5?nmol/g). Furthermore, when we included interstitial and pelagic predation, the impact of sublethal effects shifted the EC50 values even higher (7.4–10?nmol/g). Simulation results indicate that low thiamine levels, in combination with moderate to high predation, can eliminate lake trout cohorts. Our simulations suggest that the sublethal effects of low thiamine can contribute to poor lake trout recruitment more than previously suspected.     

Words of wisdom: Language use over the life span.

Two projects explored the links between language use and aging. In the first project, written or spoken text samples from disclosure studies from over 3,000 research participants from 45 different studies representing 21 laboratories in 3 countries were analyzed to determine how people change in their use of 14 text dimensions as a function of age. A separate project analyzed the collected works of 10 well-known novelists, playwrights, and poets who lived over the last 500 years. Both projects found that with increasing age, individuals use more positive and fewer negative affect words, use fewer self-references, use more future-tense and fewer past-tense verbs, and demonstrate a general pattern of increasing cognitive complexity. Implications for using language as a marker of personality among current and historical texts are discussed. (PsycINFO Database Record (c) 2010 APA, all rights reserved)